Search Results - "LUTHRA, Amit"

Structure and mechanism of a bacterial t6A biosynthesis system by Luthra, Amit, Swinehart, William, Bayooz, Susan, Phan, Phuc, Stec, Boguslaw, Iwata-Reuyl, Dirk, Swairjo, Manal A

“…Abstract The universal N(6)-threonylcarbamoyladenosine (t6A) modification at position 37 of ANN-decoding tRNAs is central to translational fidelity. In…”
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The RpoS Gatekeeper in Borrelia burgdorferi : An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity by Caimano, Melissa J, Groshong, Ashley M, Belperron, Alexia, Mao, Jialing, Hawley, Kelly L, Luthra, Amit, Graham, Danielle E, Earnhart, Christopher G, Marconi, Richard T, Bockenstedt, Linda K, Blevins, Jon S, Radolf, Justin D

“…Maintenance of within its enzootic cycle requires a complex regulatory pathway involving the alternative σ factors RpoN and RpoS and two ancillary -acting…”
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Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis by Luthra, Amit, Montezuma-Rusca, Jairo M, La Vake, Carson J, LeDoyt, Morgan, Delgado, Kristina N, Davenport, Timothy C, Fiel-Gan, Mary, Caimano, Melissa J, Radolf, Justin D, Hawley, Kelly L

“…Deconvolution of syphilis pathogenesis and selection of candidate syphilis vaccinogens requires detailed knowledge of the molecular architecture of the…”
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PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi by Groshong, Ashley M, Grassmann, André A, Luthra, Amit, McLain, Melissa A, Provatas, Anthony A, Radolf, Justin D, Caimano, Melissa J

“…In this study, we examined the relationship between c-di-GMP and its only known effector protein, PlzA, in Borrelia burgdorferi during the arthropod and…”
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Surface Immunolabeling and Consensus Computational Framework To Identify Candidate Rare Outer Membrane Proteins of Treponema pallidum by COX, David L, LUTHRA, Amit, DUNHAM-EMS, Star, DESROSIERS, Daniel C, SALAZAR, Juan C, CAIMANO, Melissa J, RADOLF, Justin D

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Extracellular Loops of the Treponema pallidum FadL Orthologs TP0856 and TP0858 Elicit IgG Antibodies and IgG + -Specific B-Cells in the Rabbit Model of Experimental Syphilis by Delgado, Kristina N, Montezuma-Rusca, Jairo M, Orbe, Isabel C, Caimano, Melissa J, La Vake, Carson J, Luthra, Amit, Hennelly, Christopher M, Nindo, Fredrick N, Meyer, Jacob W, Jones, Letitia D, Parr, Jonathan B, Salazar, Juan C, Moody, M Anthony, Radolf, Justin D, Hawley, Kelly L

“…The resurgence of syphilis in the new millennium has called attention to the importance of a vaccine for global containment strategies. Studies with immune…”
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Structural Modeling and Physicochemical Characterization Provide Evidence that P66 Forms a β-Barrel in the Borrelia burgdorferi Outer Membrane by Kenedy, Melisha R, Luthra, Amit, Anand, Arvind, Dunn, Joshua P, Radolf, Justin D, Akins, Darrin R

“…Classifications Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Characterization of Rv3868, an Essential Hypothetical Protein of the ESX-1 Secretion System in Mycobacterium tuberculosis by Luthra, Amit, Mahmood, Anjum, Arora, Ashish, Ramachandran, Ravishankar

“…Rv3868, a conserved hypothetical protein of the ESAT-6 secretion system of Mycobacterium tuberculosis, is essential for the secretion of at least four…”
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TprC/D (Tp0117/131), a Trimeric, Pore-Forming Rare Outer Membrane Protein of Treponema pallidum, Has a Bipartite Domain Structure by Anand, Arvind, Luthra, Amit, Dunham-Ems, Star, Caimano, Melissa J, Karanian, Carson, LeDoyt, Morgan, Cruz, Adriana R, Salazar, Juan C, Radolf, Justin D

“…Identification of Treponema pallidum rare outer membrane proteins (OMPs) has been a longstanding objective of syphilis researchers. We recently developed a…”
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Major Outer Sheath Protein (Msp) of Treponema denticola Has a Bipartite Domain Architecture and Exists as Periplasmic and Outer Membrane-Spanning Conformers by Anand, Arvind, Luthra, Amit, Edmond, Maxwell E, Ledoyt, Morgan, Caimano, Melissa J, Radolf, Justin D

“…The major outer sheath protein (Msp) is a primary virulence determinant in Treponema denticola, as well as the parental ortholog for the Treponema pallidum…”
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Subconjunctival hemorrhage post hyaluronic acid filler for cheeks and tear trough deformity by Luthra, Amit

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Socio-economic & technical assessment of photovoltaic powered membrane desalination processes for India by Abraham, Tinu, Luthra, Amit

“…Fresh water crisis is evident in many parts of India, varying in scale and intensity at different times of the year. About seven states are underlain by…”
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Shaping Lips with Fillers by Luthra, Amit

“…The lips and the eyes enhance facial beauty, and they have been highlighted since time immemorial. Rejuvenating the lips with fillers, frequently hyaluronic…”
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Stage‐specific global alterations in the transcriptomes of Lyme disease spirochetes during tick feeding and following mammalian host adaptation by Iyer, Radha, Caimano, Melissa J., Luthra, Amit, Axline, David, Corona, Arianna, Iacobas, Dumitru A., Radolf, Justin D., Schwartz, Ira

“…Summary Borrelia burgdorferi, the agent of Lyme disease, is maintained in nature within an enzootic cycle involving a mammalian reservoir and an Ixodes sp…”
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Structural and functional characterization of threonylcarbamoyl adenosine biosynthesis in bacteria by Paranagama, Naduni, Luthra, Amit, Bayooz, Susan, Jeon, Youngmin, Lyumkis, Dmitry, Swairjo, Manal

“…tRNA, the central molecule of translation, is heavily modified post transcriptionally with noncanonical nucleosides that constitute ~83% of all RNA…”
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Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine by Hawley, Kelly L, Montezuma-Rusca, Jairo M, Delgado, Kristina N, Singh, Navreeta, Uversky, Vladimir N, Caimano, Melissa J, Radolf, Justin D, Luthra, Amit

“…Treponema pallidum, an obligate human pathogen, has an outer membrane (OM) whose physical properties, ultrastructure, and composition differ markedly from…”
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Evaluation of Graded Strength Glycolic Acid (GA) Facial Peel: An Indian Experience by Sehgal, Virendra N., Luthra, Amit, Aggarwal, Ashok K.

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Structural Basis of 7‐Deazaguanine Modification of DNA in Bacteria and Phage by Hellie, Eric, Alkuzweny, Sana, Bayooz, Susan, Phan, Phuc, Savage, Joshua, Luthra, Amit, Iwata-Reuyl, Dirk, Swairjo, Manal

“…Abstract only Two important modifications of tRNA, the 7‐deazaguanine nucleosides queuosine (Q) and archaeosine (G + ), are biosynthesized from GTP in bacteria…”
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Conformational communication mediates the reset step in t6A biosynthesis by Luthra, Amit, Paranagama, Naduni, Swinehart, William, Bayooz, Susan, Phan, Phuc, Quach, Vanessa, Schiffer, Jamie M, Stec, Boguslaw, Iwata-Reuyl, Dirk, Swairjo, Manal A

“…Abstract The universally conserved N6-threonylcarbamoyladenosine (t6A) modification of tRNA is essential for translational fidelity. In bacteria, t6A…”
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7-Deazaguanines in DNA: functional and structural elucidation of a DNA modification system by Gedara, Samanthi Herath, Wood, Evan, Gustafson, Andrew, Liang, Cui, Hung, Shr-Hau, Savage, Joshua, Phan, Phuc, Luthra, Amit, de Crécy-Lagard, Valérie, Dedon, Peter, Swairjo, Manal A, Iwata-Reuyl, Dirk

“…Abstract The modified nucleosides 2′-deoxy-7-cyano- and 2′-deoxy-7-amido-7-deazaguanosine (dPreQ0 and dADG, respectively) recently discovered in DNA are the…”
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