Search Results - "LUTGENS, Ludy"

Substantial lymph-vascular space invasion (LVSI) is a significant risk factor for recurrence in endometrial cancer – A pooled analysis of PORTEC 1 and 2 trials by Bosse, Tjalling, Peters, Elke E.M, Creutzberg, Carien L, Jürgenliemk-Schulz, Ina M, Jobsen, Jan J, Mens, Jan Willem M, Lutgens, Ludy C.H.W, van der Steen-Banasik, Elzbieta M, Smit, Vincent T.H.B.M, Nout, Remi A

“…Abstract Background Lymph-vascular space invasion (LVSI) is an important adverse prognostic factor in endometrial cancer (EC). However, its role in relation to…”
Get full text

Five-year quality of life of endometrial cancer patients treated in the randomised Post Operative Radiation Therapy in Endometrial Cancer (PORTEC-2) trial and comparison with norm data by Nout, Remi A, Putter, Hein, Jürgenliemk-Schulz, Ina M, Jobsen, Jan J, Lutgens, Ludy C.H.W, van der Steen-Banasik, Elzbieta M, Mens, Jan Willem M, Slot, Annerie, Stenfert Kroese, Marika C, Nijman, Hans W, van de Poll-Franse, Lonneke V, Creutzberg, Carien L

“…Abstract Background The PORTEC-2 trial showed efficacy and reduced side-effects of vaginal brachytherapy (VBT) compared with external beam pelvic radiotherapy…”
Get full text

Fifteen-Year Radiotherapy Outcomes of the Randomized PORTEC-1 Trial for Endometrial Carcinoma by Creutzberg, Carien L., M.D., Ph.D, Nout, Remi A., M.D, Lybeert, Marnix L.M., M.D, Wárlám-Rodenhuis, Carla C., M.D, Jobsen, Jan J., M.D., Ph.D, Mens, Jan-Willem M., M.D, Lutgens, Ludy C.H.W., M.D., Ph.D, Pras, Elisabeth, M.D., Ph.D, van de Poll-Franse, Lonneke V., Ph.D, van Putten, Wim L.J., M.Sc

“…Purpose To evaluate the very long-term results of the randomized Post Operative Radiation Therapy in Endometrial Carcinoma (PORTEC)-1 trial for patients with…”
Get full text

Improved Risk Assessment by Integrating Molecular and Clinicopathological Factors in Early-stage Endometrial Cancer-Combined Analysis of the PORTEC Cohorts by Stelloo, Ellen, Nout, Remi A, Osse, Elisabeth M, Jürgenliemk-Schulz, Ina J, Jobsen, Jan J, Lutgens, Ludy C, van der Steen-Banasik, Elzbieta M, Nijman, Hans W, Putter, Hein, Bosse, Tjalling, Creutzberg, Carien L, Smit, Vincent T H B M

“…Recommendations for adjuvant treatment for women with early-stage endometrial carcinoma are based on clinicopathologic features. Comprehensive genomic…”
Get full text

Prevalence and Prognosis of Lynch Syndrome and Sporadic Mismatch Repair Deficiency in Endometrial Cancer by Post, Cathalijne C B, Stelloo, Ellen, Smit, Vincent T H B M, Ruano, Dina, Tops, Carli M, Vermij, Lisa, Rutten, Tessa A, Jürgenliemk-Schulz, Ina M, Lutgens, Ludy C H W, Jobsen, Jan J, Nout, Remi A, Crosbie, Emma J, Powell, Melanie E, Mileshkin, Linda, Leary, Alexandra, Bessette, Paul, Putter, Hein, de Boer, Stephanie M, Horeweg, Nanda, Nielsen, Maartje, Wezel, Tom van, Bosse, Tjalling, Creutzberg, Carien L

“…Standard screening of endometrial cancer (EC) for Lynch syndrome (LS) is gaining traction; however, the prognostic impact of an underlying hereditary etiology…”
Get full text

Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial by de Boer, Stephanie M, Powell, Melanie E, Mileshkin, Linda, Katsaros, Dionyssios, Bessette, Paul, Haie-Meder, Christine, Ottevanger, Petronella B, Ledermann, Jonathan A, Khaw, Pearly, Colombo, Alessandro, Fyles, Anthony, Baron, Marie-Helene, Jürgenliemk-Schulz, Ina M, Kitchener, Henry C, Nijman, Hans W, Wilson, Godfrey, Brooks, Susan, Carinelli, Silvestro, Provencher, Diane, Hanzen, Chantal, Lutgens, Ludy C H W, Smit, Vincent T H B M, Singh, Naveena, Do, Viet, D'Amico, Romerai, Nout, Remi A, Feeney, Amanda, Verhoeven-Adema, Karen W, Putter, Hein, Creutzberg, Carien L, McCormack, Mary, Whitmarsh, Karen, Allerton, Rozenn, Gregory, Deborah, Symonds, Paul, Hoskin, Peter J., Adusumalli, Madhavi, Anand, Anjana, Wade, Robert, Stewart, Alexandra, Taylor, Wendy, Kruitwagen, Roy F.P.M., Hollema, Harry, Pras, Elizabeth, Snyers, An, Stalpers, Lukas, Jobsen, Jan J., Slot, Annerie, Mens, Jan-Willem M., Stam, Tanja C., Van Triest, Baukelien, Van der Steen - Banasik, Elzbieta M., De Winter, Karin A.J., Quinn, Michael A., Kolodziej, Ilka, Pyman, Jan, Johnson, Carol, Capp, Anne, Fossati, Roldano, Gribaudo, Sergio, Lissoni, Andrea A., Ferrero, Annamaria, Artioli, Grazia, Davidson, Cathy, McLachlin, C. Meg, Ghatage, Prafull, Rittenberg, Paula V.C., Souhami, Luis, Thomas, Gillian, Duvillard, Pierre, Berton-Rigaud, Dominique, Tubiana-Mathieu, Nicole

“…Although women with endometrial cancer generally have a favourable prognosis, those with high-risk disease features are at increased risk of recurrence. The…”
Get full text

Quality of Life After Pelvic Radiotherapy or Vaginal Brachytherapy for Endometrial Cancer: First Results of the Randomized PORTEC-2 Trial by NOUT, Remi A, PUTTER, Hein, SMIT, Vincent T. H. B. M, NIJMAN, Hans W, VAN DEN TOL, Philine P, CREUTZBERG, Carien L, JÜRGENLIEMK-SCHULZ, Ina M, JOBSEN, Jan J, LUTGENS, Ludy C. H. W, VAN DER STEEN-BANASIK, Elzbieta M, MENS, Jan Willem M, SLOT, Annerie, STENFERT KROESE, Marika C, VAN BUNNINGEN, BartN. F. M

“…PURPOSE Studies on quality of life (QOL) among women with endometrial cancer have shown that patients who undergo pelvic radiotherapy report lower role…”
Get full text

Long-Term Outcome and Quality of Life of Patients With Endometrial Carcinoma Treated With or Without Pelvic Radiotherapy in the Post Operative Radiation Therapy in Endometrial Carcinoma 1 (PORTEC-1) Trial by Nout, Remi A, van de Poll-Franse, Lonneke V, Lybeert, Marnix L M, Wárlám-Rodenhuis, Carla C, Jobsen, Jan J, Mens, Jan Willem M, Lutgens, Ludy C H W, Pras, Betty, van Putten, Wim L J, Creutzberg, Carien L

“…To determine the long-term outcome and health-related quality of life (HRQL) of patients with endometrial carcinoma (EC) treated with or without pelvic…”
Get full text

Defining Substantial Lymphovascular Space Invasion in Endometrial Cancer by Peters, Elke E.M., León-Castillo, Alicia, Smit, Vincent T.H.B.M., Boennelycke, Marie, Hogdall, Estrid, Hogdall, Claus, Creutzberg, Carien, Jürgenliemk-Schulz, Ina M., Jobsen, Jan J., Mens, Jan Willem M., Lutgens, Ludy C.H.W., van der Steen-Banasik, Elzbieta M., Ortoft, Gitte, Bosse, Tjalling, Nout, Remi

“…Lymphovascular space invasion (LVSI) occurs in a minority of endometrial cancer (EC) cases, and the extent of LVSI is an important risk factor for recurrence…”
Get full text

Prognostic impact and causality of age on oncological outcomes in women with endometrial cancer: a multimethod analysis of the randomised PORTEC-1, PORTEC-2, and PORTEC-3 trials by Wakkerman, Famke C, Wu, Jiqing, Putter, Hein, Jürgenliemk-Schulz, Ina M, Jobsen, Jan J, Lutgens, Ludy C H W, Haverkort, Marie A D, de Jong, Marianne A, Mens, Jan Willem M, Wortman, Bastiaan G, Nout, Remi A, Léon-Castillo, Alicia, Powell, Melanie E, Mileshkin, Linda R, Katsaros, Dionyssios, Alfieri, Joanne, Leary, Alexandra, Singh, Naveena, de Boer, Stephanie M, Nijman, Hans W, Smit, Vincent T H B M, Bosse, Tjalling, Koelzer, Viktor H, Creutzberg, Carien L, Horeweg, Nanda

“…Numerous studies have shown that older women with endometrial cancer have a higher risk of recurrence and cancer-related death. However, it remains unclear…”
Get full text

Radiation therapy combined with hyperthermia versus cisplatin for locally advanced cervical cancer: Results of the randomized RADCHOC trial by Lutgens, Ludy C.H.W, Koper, Peter C.M, Jobsen, Jan J, van der Steen-Banasik, Elzbieta M, Creutzberg, Carien L, van den Berg, Hetty A, Ottevanger, Petronella B, van Rhoon, Gerard C, van Doorn, Helena C, Houben, Ruud, van der Zee, Jacoba

“…Abstract Background Chemoradiation (RT-CT) is standard treatment for locally advanced cervical cancer (LACC). This study tried to establish if radiotherapy…”
Get full text

Nomograms for Prediction of Outcome With or Without Adjuvant Radiation Therapy for Patients With Endometrial Cancer: A Pooled Analysis of PORTEC-1 and PORTEC-2 Trials by Creutzberg, Carien L., MD, PhD, van Stiphout, Ruud G.P.M., MSc, PhD, Nout, Remi A., MD, PhD, Lutgens, Ludy C.H.W., MD, PhD, Jürgenliemk-Schulz, Ina M., MD, PhD, Jobsen, Jan J., MD, PhD, Smit, Vincent T.H.B.M., MD, PhD, Lambin, Philippe, MD, PhD

“…Background Postoperative radiation therapy for stage I endometrial cancer improves locoregional control but is without survival benefit. To facilitate…”
Get full text

Association of persistent morbidity after radiotherapy with quality of life in locally advanced cervical cancer survivors by Spampinato, Sofia, Tanderup, Kari, Lindegaard, Jacob C., Schmid, Maximilian P., Sturdza, Alina, Segedin, Barbara, Jürgenliemk-Schulz, Ina M., De Leeuw, Astrid, Bruheim, Kjersti, Mahantshetty, Umesh, Chargari, Cyrus, Rai, Bhavana, Cooper, Rachel, van der Steen-Banasik, Elzbieta, Sundset, Marit, Wiebe, Ericka, Villafranca, Elena, Van Limbergen, Erik, Pieters, Bradley R., Tee Tan, Li, Lutgens, Ludy C.H.W., Hoskin, Peter, Smet, Stéphanie, Pötter, Richard, Nout, Remi, Chopra, Supriya, Kirchheiner, Kathrin

“…•Impact of morbidity on quality of life (QOL) of cancer survivors depends on severity and persistence.•Prospective data from EMBRACE-I allowed to assess the…”
Get full text

Radiation Therapy Techniques and Treatment-Related Toxicity in the PORTEC-3 Trial: Comparison of 3-Dimensional Conformal Radiation Therapy Versus Intensity-Modulated Radiation Therapy by Wortman, Bastiaan G., Post, Cathalijne C.B., Powell, Melanie E., Khaw, Pearly, Fyles, Anthony, D'Amico, Romerai, Haie-Meder, Christine, Jürgenliemk-Schulz, Ina M., McCormack, Mary, Do, Viet, Katsaros, Dionyssios, Bessette, Paul, Baron, Marie Hélène, Nout, Remi A., Whitmarsh, Karen, Mileshkin, Linda, Lutgens, Ludy C.H.W., Kitchener, Henry C., Brooks, Susan, Nijman, Hans W., Astreinidou, Eleftheria, Putter, Hein, Creutzberg, Carien L., de Boer, Stephanie M.

“…Radiation therapy techniques have developed from 3-dimensional conformal radiation therapy (3DCRT) to intensity modulated radiation therapy (IMRT), with better…”
Get full text

Severity and Persistency of Late Gastrointestinal Morbidity in Locally Advanced Cervical Cancer: Lessons Learned From EMBRACE-I and Implications for the Future by Spampinato, Sofia, Jensen, Nina B.K., Pötter, Richard, Fokdal, Lars U., Chargari, Cyrus, Lindegaard, Jacob C., Schmid, Maximilian P., Sturdza, Alina, Jürgenliemk-Schulz, Ina M., Mahantshetty, Umesh, Hoskin, Peter, Segedin, Barbara, Rai, Bhavana, Bruheim, Kjersti, Wiebe, Ericka, Van der Steen-Banasik, Elzbieta, Cooper, Rachel, Van Limbergen, Erik, Sundset, Marit, Pieters, Bradley R., Lutgens, Ludy C.H.W., Tan, Li Tee, Villafranca, Elena, Smet, Stéphanie, Jastaniyah, Noha, Nout, Remi A., Kirisits, Christian, Chopra, Supriya, Kirchheiner, Kathrin, Tanderup, Kari, EMBRACE Collaborative Group

“…The purpose was to evaluate patient- and treatment-related risk factors for physician-assessed and patient-reported gastrointestinal (GI) symptoms after…”
Get full text

Confirmation of thermal dose as a predictor of local control in cervical carcinoma patients treated with state-of-the-art radiation therapy and hyperthermia by Kroesen, Michiel, Mulder, Hendrik T., van Holthe, Jeanette M.L., Aangeenbrug, Aleida A., Mens, Jan Willem M., van Doorn, Helena C., Paulides, Margarethus M., Oomen-de Hoop, Esther, Vernhout, Rene M., Lutgens, Ludy C., van Rhoon, Gerard C., Franckena, Martine

“…•Significant local control improvement in cervical cancer patients due to hyperthermia was validated in a recent patient cohort.•Hyperthermia is effective in…”
Get full text

Prediction of recurrence risk in endometrial cancer with multimodal deep learning by Volinsky-Fremond, Sarah, Horeweg, Nanda, Andani, Sonali, Barkey Wolf, Jurriaan, Lafarge, Maxime W., de Kroon, Cor D., Ørtoft, Gitte, Høgdall, Estrid, Dijkstra, Jouke, Jobsen, Jan J., Lutgens, Ludy C. H. W., Powell, Melanie E., Mileshkin, Linda R., Mackay, Helen, Leary, Alexandra, Katsaros, Dionyssios, Nijman, Hans W., de Boer, Stephanie M., Nout, Remi A., de Bruyn, Marco, Church, David, Smit, Vincent T. H. B. M., Creutzberg, Carien L., Koelzer, Viktor H., Bosse, Tjalling

“…Predicting distant recurrence of endometrial cancer (EC) is crucial for personalized adjuvant treatment. The current gold standard of combined pathological and…”
Get full text

Efficacy of a nurse-led sexual rehabilitation intervention for women with gynaecological cancers receiving radiotherapy: results of a randomised trial by Suvaal, Isabelle, Hummel, Susanna B., Mens, Jan-Willem M., Tuijnman-Raasveld, Charlotte C., Tsonaka, Roula, Velema, Laura A., Westerveld, Henrike, Cnossen, Jeltsje S., Snyers, An, Jürgenliemk-Schulz, Ina M., Lutgens, Ludy C. H. W., Beukema, Jannet C., Haverkort, Marie A. D., Nowee, Marlies E., Nout, Remi A., de Kroon, Cor D., van den Hout, Wilbert B., Creutzberg, Carien L., van Doorn, Helena C., ter Kuile, Moniek M.

“…Background The multicentre randomised SPARC trial evaluated the efficacy of a nurse-led sexual rehabilitation intervention on sexual functioning, distress,…”
Get full text

Author Correction: Prediction of recurrence risk in endometrial cancer with multimodal deep learning by Volinsky-Fremond, Sarah, Horeweg, Nanda, Andani, Sonali, Barkey Wolf, Jurriaan, Lafarge, Maxime W., de Kroon, Cor D., Ørtoft, Gitte, Høgdall, Estrid, Dijkstra, Jouke, Jobsen, Jan J., Lutgens, Ludy C. H. W., Powell, Melanie E., Mileshkin, Linda R., Mackay, Helen, Leary, Alexandra, Katsaros, Dionyssios, Nijman, Hans W., de Boer, Stephanie M., Nout, Remi A., de Bruyn, Marco, Church, David, Smit, Vincent T. H. B. M., Creutzberg, Carien L., Koelzer, Viktor H., Bosse, Tjalling

Get full text

Prognostic Integrated Image-Based Immune and Molecular Profiling in Early-Stage Endometrial Cancer by Horeweg, Nanda, de Bruyn, Marco, Nout, Remi A, Stelloo, Ellen, Kedziersza, Katarzyna, León-Castillo, Alicia, Plat, Annechien, Mertz, Kirsten D, Osse, Michelle, Jürgenliemk-Schulz, Ina M, Lutgens, Ludy C H W, Jobsen, Jan J, van der Steen-Banasik, Elzbieta M, Smit, Vincent T, Creutzberg, Carien L, Bosse, Tjalling, Nijman, Hans W, Koelzer, Viktor H, Church, David N

“…Optimum risk stratification in early-stage endometrial cancer combines clinicopathologic factors and the molecular endometrial cancer classification defined by…”
Get more information