Search Results - "LUST, GEORGE"

A novel iterative mixed model to remap three complex orthopedic traits in dogs by Huang, Meng, Hayward, Jessica J, Corey, Elizabeth, Garrison, Susan J, Wagner, Gabriela R, Krotscheck, Ursula, Hayashi, Kei, Schweitzer, Peter A, Lust, George, Boyko, Adam R, Todhunter, Rory J

“…Hip dysplasia (HD), elbow dysplasia (ED), and rupture of the cranial (anterior) cruciate ligament (RCCL) are the most common complex orthopedic traits of dogs…”
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Retrospective analysis for genetic improvement of hip joints of cohort labrador retrievers in the United States: 1970-2007 by Hou, Yali, Wang, Yachun, Lust, George, Zhu, Lan, Zhang, Zhiwu, Todhunter, Rory J

“…Canine Hip Dysplasia (CHD) is a common inherited disease that affects dog wellbeing and causes a heavy financial and emotional burden to dog owners and…”
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Effects of diet restriction on life span and age-related changes in dogs by Kealy, Richard D, Lawler, Dennis F, Ballam, Joan M, Mantz, Sandra L, Biery, Darryl N, Greeley, Elizabeth H, Lust, George, Segre, Mariangela, Smith, Gail K, Stowe, Howard D

“…To evaluate the effects of 25% diet restriction on life span of dogs and on markers of aging. Paired feeding study. 48 Labrador Retrievers. Dogs were paired,…”
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Differential genetic regulation of canine hip dysplasia and osteoarthritis by Zhou, Zhengkui, Sheng, Xihui, Zhang, Zhiwu, Zhao, Keyan, Zhu, Lan, Guo, Gang, Friedenberg, Steve G, Hunter, Linda S, Vandenberg-Foels, Wendy S, Hornbuckle, William E, Krotscheck, Ursula, Corey, Elizabeth, Moise, Nancy S, Dykes, Nathan L, Li, Junya, Xu, Shangzhong, Du, Lixin, Wang, Yachun, Sandler, Jody, Acland, Gregory M, Lust, George, Todhunter, Rory J

“…Canine hip dysplasia (HD) is a common polygenic trait characterized by hip malformation that results in osteoarthritis (OA). The condition in dogs is very…”
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Linkage and segregation analysis of black and brindle coat color in domestic dogs by Kerns, J.A, Cargill, E.J, Clark, L.A, Candille, S.I, Berryere, T.G, Olivier, M, Lust, G, Todhunter, R.J, Schmutz, S.M, Murphy, K.E

“…Mutations of pigment type switching have provided basic insight into melanocortin physiology and evolutionary adaptation. In all vertebrates that have been…”
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Chondrocyte necrosis and apoptosis in impact damaged articular cartilage by Chen, Chih-Tung, Burton-Wurster, Nancy, Borden, Caroline, Hueffer, Karsten, Bloom, Stephen E, Lust, George

“…A decrease in chondrocyte numbers is one characteristic of osteoarthritic cartilage. This decrease may be the result of apoptosis or other forms of cell death…”
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Origin of cartilage laminae in MRI by Xia, Y, Farquhar, T, Burton-Wurster, N, Lust, G

“…To understand the origin of the laminated appearance of cartilage in MRI (the magic angle effect), microscopic MRI (mu MRI) experiments were performed at…”
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Compositional and metabolic changes in damaged cartilage are peak-stress, stress-rate, and loading-duration dependent by Chen, C T, Burton-Wurster, N, Lust, G, Bank, R A, Tekoppele, J M

“…The first objective of this study was to determine if the cumulative effects of impact or smoothly arising compression would damage the matrix of articular…”
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Evaluation of the effect of limited food consumption on radiographic evidence of osteoarthritis in dogs by Kealy, R D, Lawler, D F, Ballam, J M, Lust, G, Biery, D N, Smith, G K, Mantz, S L

“…To determine prevalence of radiographic evidence of osteoarthritis in 4 diarthrodial joints of dogs with restricted feed intake, compared with dogs without…”
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Morphological Changes in Articular Cartilage Due to Static Compression: Polarized Light Microscopy Study by Alhadlaq, Hisham A., Xia, Yang, Hansen, Fay M., Les, Clifford M., Lust, George

“…We studied the deformation of the extracellular matrices in articular cartilage using a new compression-preservation method in histology. A Hoffman clamp was…”
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Quantitative trait loci for hip dysplasia in a crossbreed canine pedigree by Todhunter, Rory J., Mateescu, Raluca, Lust, George, Burton-Wurster, Nancy I., Dykes, Nathan L., Bliss, Stuart P., Williams, Alma J., Vernier-Singer, Margaret, Corey, Elizabeth, Harjes, Carlos, Quaas, Richard L., Zhang, Zhiwu, Gilbert, Robert O., Volkman, Dietrich, Casella, George, Wu, Rongling, Acland, Gregory M.

“…Canine hip dysplasia is a common developmental inherited trait characterized by hip laxity, subluxation or incongruity of the femoral head and acetabulum in…”
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Characterization of cartilage metabolic response to static and dynamic stress using a mechanical explant test system by Torzilli, Peter A., Grigiene, Rita, Huang, Charles, Friedman, Steven M., Doty, Stephen B., Boskey, Adele L., Lust, George

“…A new mechanical explant test system was used to study the metabolic response (via proteoglycan biosynthesis) of mature, weight-bearing canine articular…”
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Chondrocyte-fibrin matrix transplants for resurfacing extensive articular cartilage defects by Hendrickson, D A, Nixon, A J, Grande, D A, Todhunter, R J, Minor, R M, Erb, H, Lust, G

“…Cartilage resurfacing by chondrocyte implantation, with fibrin used as a vehicle, was examined in large (12 mm) full-thickness articular cartilage defects in…”
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Comparison of three radiographic methods for diagnosis of hip dysplasia in eight-month-old dogs by Lust, G, Todhunter, R J, Erb, H N, Dykes, N L, Williams, A J, Burton-Wurster, N I, Farese, J P

“…To compare the accuracy of the extended-hip radiographic (EHR) score, the distraction index (DI), and the dorsolateral subluxation (DLS) score for identifying…”
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The Cartilage-specific Fibronectin Isoform Has a High Affinity Binding Site for the Small Proteoglycan Decorin by Gendelman, Rina, Burton-Wurster, Nancy I, MacLeod, James N, Lust, George

“…Binding of fibronectin to the small proteoglycan decorin plays an important role in cell differentiation and cell migration. The cartilage-specific (V+C) −…”
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Fibronectin mRNA Splice Variant in Articular Cartilage Lacks Bases Encoding the V, III-15, and I-10 Protein Segments by MacLeod, James N., Burton-Wurster, Nancy, Gu, Da Nian, Lust, George

“…Fibronectin is an extracellular matrix glycoprotein encoded by a single gene. Alternative RNA splicing has been reported at three sites, ED (extra type III…”
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Effect of compressive loading and unloading on the synthesis of total protein, proteoglycan, and fibronectin by canine cartilage explants by Burton-Wurster, N, Vernier-Singer, M, Farquhar, T, Lust, G

“…Full-thickness canine articular cartilage explants were subjected to compressive loads equivalent to a uniaxial stress of 0.025-1.2 MPa. A single cycle (18 h)…”
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Evaluation of multiple radiographic predictors of cartilage lesions in the hip joints of eight-month-old dogs by Todhunter, Rory J, Grohn, Yjo T, Bliss, Stuart P, Wilfand, Ashley, Williams, Alma J, Vernier-Singer, Margaret, Burton-Wurster, Nancy I, Dykes, Nathan L, Wu, Rongling, Casella, George, Acland, Gregory M, Lust, George

“…To determine the radiographic methods that best predict the development of osteoarthritis in the hip joints of a cohort of dogs with hip dysplasia and…”
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Canine hip dysplasia: Another perspective by Lust, George

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Effect of dorsal hip loading, sedation, and general anesthesia on the dorsolateral subluxation score in dogs by Todhunter, R.J, Bertram, J.E, Smith, S, Farese, J.P, Williams, A.J, Manocchia, A, Erb, H.N, Dykes, N.L, Burton-Wurster, N.I, Lust, G

“…Objective— To determine whether dorsal loading of the pelvis and type of chemical restraint affected the dorsolateral subluxation (DLS) score of dog hips…”
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