Search Results - "LUSSIER, A"

MicroRNA expression characterizes oligometastasis(es) by Lussier, Yves A, Xing, H Rosie, Salama, Joseph K, Khodarev, Nikolai N, Huang, Yong, Zhang, Qingbei, Khan, Sajid A, Yang, Xinan, Hasselle, Michael D, Darga, Thomas E, Malik, Renuka, Fan, Hanli, Perakis, Samantha, Filippo, Matthew, Corbin, Kimberly, Lee, Younghee, Posner, Mitchell C, Chmura, Steven J, Hellman, Samuel, Weichselbaum, Ralph R

“…Cancer staging and treatment presumes a division into localized or metastatic disease. We proposed an intermediate state defined by ≤ 5 cumulative…”
Get full text

Intersection of Epigenetic and Immune Alterations: Implications for Fetal Alcohol Spectrum Disorder and Mental Health by Lussier, Alexandre A, Bodnar, Tamara S, Weinberg, Joanne

“…Prenatal alcohol exposure can impact virtually all body systems, resulting in a host of structural, neurocognitive, and behavioral abnormalities. Among the…”
Get full text

Sensitive period-regulating genetic pathways and exposure to adversity shape risk for depression by Zhu, Yiwen, Wang, Min-Jung, Crawford, Katherine M, Ramírez-Tapia, Juan Carlos, Lussier, Alexandre A, Davis, Kathryn A, de Leeuw, Christiaan, Takesian, Anne E, Hensch, Takao K, Smoller, Jordan W, Dunn, Erin C

“…Animal and human studies have documented the existence of developmental windows (or sensitive periods) when experience can have lasting effects on brain…”
Get full text

Autosomal sex-associated co-methylated regions predict biological sex from DNA methylation by Gatev, Evan, Inkster, Amy M, Negri, Gian Luca, Konwar, Chaini, Lussier, Alexandre A, Skakkebaek, Anne, Sokolowski, Marla B, Gravholt, Claus H, Dunn, Erin C, Kobor, Michael S, Aristizabal, Maria J

“…Abstract Sex is a modulator of health that has been historically overlooked in biomedical research. Recognizing this knowledge gap, funding agencies now…”
Get full text

Oligo- and polymetastatic progression in lung metastasis(es) patients is associated with specific microRNAs by Lussier, Yves A, Khodarev, Nikolai N, Regan, Kelly, Corbin, Kimberly, Li, Haiquan, Ganai, Sabha, Khan, Sajid A, Gnerlich, Jennifer L, Gnerlich, Jennifer, Darga, Thomas E, Fan, Hanli, Karpenko, Oleksiy, Paty, Philip B, Posner, Mitchell C, Chmura, Steven J, Hellman, Samuel, Ferguson, Mark K, Weichselbaum, Ralph R

“…Strategies to stage and treat cancer rely on a presumption of either localized or widespread metastatic disease. An intermediate state of metastasis termed…”
Get full text

Zero Thermal Expansion in ZrMgMo3O12: NMR Crystallography Reveals Origins of Thermoelastic Properties by Romao, Carl P, Perras, Frédéric A, Werner-Zwanziger, Ulrike, Lussier, Joey A, Miller, Kimberly J, Calahoo, Courtney M, Zwanziger, Josef W, Bieringer, Mario, Marinkovic, Bojan A, Bryce, David L, White, Mary Anne

“…The coefficient of thermal expansion of ZrMgMo3O12 has been measured and was found to be extremely close to zero over a wide temperature range including room…”
Get full text

The emergence of genome-based drug repositioning by Lussier, Yves A, Chen, James L

“…In a pair of papers in this issue of Science Translational Medicine, Butte et al. provide a concrete example of how reinterpreting and comparing genome-wide…”
Get more information

LiNbO3‐Type Polar Antiferromagnet InVO3 Synthesized under High‐Pressure Conditions by Tan, Zhenhong, Lussier, Joey A., Yamada, Takumi, Xu, Yuanhui, Saito, Takashi, Goto, Masato, Kosugi, Yoshihisa, Vrublevskiy, Dmitry, Kanemitsu, Yoshihiko, Bieringer, Mario, Shimakawa, Yuichi

“…The ambient pressure cation disordered InVO3 bixbyite has been predicted to form a GdFeO3‐type perovskite phase under high pressure and high temperature…”
Get full text

Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis by Lee, Younghee, Yang, Xinan, Huang, Yong, Fan, Hanli, Zhang, Qingbei, Wu, Youngfei, Li, Jianrong, Hasina, Rifat, Cheng, Chao, Lingen, Mark W, Gerstein, Mark B, Weichselbaum, Ralph R, Xing, H Rosie, Lussier, Yves A

“…Due to the large number of putative microRNA gene targets predicted by sequence-alignment databases and the relative low accuracy of such predictions which are…”
Get full text

binomialRF: interpretable combinatoric efficiency of random forests to identify biomarker interactions by Rachid Zaim, Samir, Kenost, Colleen, Berghout, Joanne, Chiu, Wesley, Wilson, Liam, Zhang, Hao Helen, Lussier, Yves A

“…In this era of data science-driven bioinformatics, machine learning research has focused on feature selection as users want more interpretation and post-hoc…”
Get full text

Correction to: binomialRF: interpretable combinatoric efficiency of random forests to identify biomarker interactions by Zaim, Samir Rachid, Kenost, Colleen, Berghout, Joanne, Chiu, Wesley, Wilson, Liam, Zhang, Hao Helen, Lussier, Yves A

“…An amendment to this paper has been published and can be accessed via the original article…”
Get full text

Updates to data versions and analytic methods influence the reproducibility of results from epigenome-wide association studies by Lussier, Alexandre A., Zhu, Yiwen, Smith, Brooke J., Simpkin, Andrew J., Smith, Andrew D.A.C., Suderman, Matthew J., Walton, Esther, Ressler, Kerry J., Dunn, Erin C.

“…Biomedical research has grown increasingly cooperative through the sharing of consortia-level epigenetic data. Since consortia preprocess data prior to…”
Get full text

DNA methylation as a predictor of fetal alcohol spectrum disorder by Lussier, Alexandre A, Morin, Alexander M, MacIsaac, Julia L, Salmon, Jenny, Weinberg, Joanne, Reynolds, James N, Pavlidis, Paul, Chudley, Albert E, Kobor, Michael S

“…Fetal alcohol spectrum disorder (FASD) is a developmental disorder that manifests through a range of cognitive, adaptive, physiological, and neurobiological…”
Get full text

DNA methylation signature of human fetal alcohol spectrum disorder by Portales-Casamar, Elodie, Lussier, Alexandre A, Jones, Meaghan J, MacIsaac, Julia L, Edgar, Rachel D, Mah, Sarah M, Barhdadi, Amina, Provost, Sylvie, Lemieux-Perreault, Louis-Philippe, Cynader, Max S, Chudley, Albert E, Dubé, Marie-Pierre, Reynolds, James N, Pavlidis, Paul, Kobor, Michael S

“…Prenatal alcohol exposure is the leading preventable cause of behavioral and cognitive deficits, which may affect between 2 and 5 % of children in North…”
Get full text

Exprtarget: an integrative approach to predicting human microRNA targets by Gamazon, Eric R, Im, Hae-Kyung, Duan, Shiwei, Lussier, Yves A, Cox, Nancy J, Dolan, M Eileen, Zhang, Wei

“…Variation in gene expression has been observed in natural populations and associated with complex traits or phenotypes such as disease susceptibility and drug…”
Get full text

Altered GABAergic and glutamatergic activity within the rat hippocampus and amygdala in rats subjected to repeated corticosterone administration but not restraint stress by Lussier, A.L, Romay-Tallón, R, Caruncho, H.J, Kalynchuk, L.E

“…Highlights ► We studied the effect of corticosterone and restraint stress on GABA and glutamate. ► CORT decreased GAD65 and the α2 subunit and increased VGLUT2…”
Get full text

Variants affecting exon skipping contribute to complex traits by Lee, Younghee, Gamazon, Eric R, Rebman, Ellen, Lee, Yeunsook, Lee, Sanghyuk, Dolan, M Eileen, Cox, Nancy J, Lussier, Yves A

“…DNA variants that affect alternative splicing and the relative quantities of different gene transcripts have been shown to be risk alleles for some Mendelian…”
Get full text

Extracellular proteolysis of reelin by tissue plasminogen activator following synaptic potentiation by Trotter, J.H, Lussier, A.L, Psilos, K.E, Mahoney, H.L, Sponaugle, A.E, Hoe, H.-S, Rebeck, G.W, Weeber, E.J

“…Highlights • Reelin is important in adult synaptic plasticity and learning and memory. • How reelin is regulated remains to be elucidated. • tPA KO mice do not…”
Get full text

Childhood Emotional Neglect and Adolescent Depression: Assessing the Protective Role of Peer Social Support in a Longitudinal Birth Cohort by Glickman, Emma A, Choi, Karmel W, Lussier, Alexandre A, Smith, Brooke J, Dunn, Erin C

“…Childhood adversities have been shown to increase psychopathology risk, including depression. However, the specific impact of childhood emotional neglect on…”
Get full text

Topotactic Solid-State Metal Hydride Reductions of Sr2MnO4 by Hernden, Bradley C, Lussier, Joey A, Bieringer, Mario

“…We report novel details regarding the reactivity and mechanism of the solid-state topotactic reduction of Sr2MnO4 using a series of solid-state metal hydrides…”
Get full text