Paediatric experience with acetate-free biofiltration

Paediatric experience with acetate-free biofiltration

We describe our preliminary experience with five children who received acetate-free biofiltration, a modification of haemodiafiltration without buffer in the dialysate and simultaneous infusion of bicarbonate through a venous port. Adequacy of haemodialysis (HD) was achieved with 3 h treatments thre...

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) Vol. 9; no. 3; pp. 357 - 358
Main Authors: ESPINO HERNANDEZ, M, MORALES SAN JOSE, D, LUQUE DE PABLOS, J. A
Format: Journal Article
Language:English
Published: Heidelberg Springer 01-06-1995
Subjects:
Adolescent
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Bicarbonates - therapeutic use
Biological and medical sciences
Blood Flow Velocity
Body Weight
Child
Emergency and intensive care: renal failure. Dialysis management
Female
Hemodiafiltration - methods
Humans
Hydrogen-Ion Concentration
Infusions, Intravenous
Intensive care medicine
Kidney Failure, Chronic - metabolism
Kidney Failure, Chronic - physiopathology
Kidney Failure, Chronic - therapy
Male
Medical sciences
Proteins - metabolism
Regression Analysis
Human
Extrarenal dialysis
Acid base balance
Treatment
Hemodiafiltration
Hemodialysis
Dialysis fluid
Chemical composition
Technique
Child
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Summary:We describe our preliminary experience with five children who received acetate-free biofiltration, a modification of haemodiafiltration without buffer in the dialysate and simultaneous infusion of bicarbonate through a venous port. Adequacy of haemodialysis (HD) was achieved with 3 h treatments three times per week (mean Kt/v 1.35 +/- 0.29, mean protein catabolic rate (PCR) 1.4 +/- 0.3 mg/dl). During the session, pH increased from 7.4 pre HD to 7.5 post HD. The mean bicarbonate infused as a 0.166 M solution averaged 235 +/- 35 mEq/h. Hypertension did not occur. There were no cramps, hypotension or vomiting. Bicarbonate requirements correlated significantly with dialyser surface area and body weight (r = 0.76, P < 0.001).
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0931-041X
1432-198X
DOI:10.1007/BF02254213