Search Results - "LUPI, Monica"

Local Health Department Values and Organizational Authorities Guiding Cross-Sector Work During COVID-19 by Johnson, Karl, Biddell, Caitlin B., Gora Combs, Katherine, Wiesman, John, Valdes Lupi, Monica, Hassmiller Lich, Kristen

“…Objective The COVID-19 pandemic highlighted the role that local health departments (LHDs) have in cross sector can address alone, including the work of value…”
Get full text

DNA Damage Response Inhibitor Combinations Exert Synergistic Antitumor Activity in Aggressive B-Cell Lymphomas by Restelli, Valentina, Lupi, Monica, Chilà, Rosaria, Vagni, Micaela, Tarantelli, Chiara, Spriano, Filippo, Gaudio, Eugenio, Bertoni, Francesco, Damia, Giovanna, Carrassa, Laura

“…The DNA damage response (DDR) kinases ATR, Chk1, and Wee1 play vital roles in the response to replication stress and in maintaining cancer genomic stability…”
Get full text

Combined inhibition of Chk1 and Wee1: In vitro synergistic effect translates to tumor growth inhibition in vivo by Carrassa, Laura, Chilà, Rosaria, Lupi, Monica, Ricci, Francesca, Celenza, Cinzia, Mazzoletti, Marco, Broggini, Massimo, Damia, Giovanna

“…Targeting Chk1 protein kinase can enhance the antitumor effects of radio- and chemotherapy. Recent evidence disclosed a role of Chk1 in unperturbed cell…”
Get full text

ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells by Portale, Federica, Cricrì, Giulia, Bresolin, Silvia, Lupi, Monica, Gaspari, Stefania, Silvestri, Daniela, Russo, Barbara, Marino, Noemi, Ubezio, Paolo, Pagni, Fabio, Vergani, Patrizia, Kronnie, Geertruy Te, Valsecchi, Maria Grazia, Locatelli, Franco, Rizzari, Carmelo, Biondi, Andrea, Dander, Erica, D'Amico, Giovanna

“…B-cell precursor-acute lymphoblastic leukemia modulates the bone marrow (BM) niche to become leukemia-supporting and chemo-protective by reprogramming the…”
Get full text

Using Data to Advance Workforce Development in Public Health Agencies: Perspectives From State and Local Health Officials by McKeown, Karen, Matthies, Robin, Valdes Lupi, Monica, Mortell, Tricia

Get full text

Epithelioid Pleural Mesothelioma Is Characterized by Tertiary Lymphoid Structures in Long Survivors: Results from the MATCH Study by Mannarino, Laura, Paracchini, Lara, Pezzuto, Federica, Olteanu, Gheorghe Emilian, Moracci, Laura, Vedovelli, Luca, De Simone, Irene, Bosetti, Cristina, Lupi, Monica, Amodeo, Rosy, Inglesi, Alessia, Callari, Maurizio, Penpa, Serena, Libener, Roberta, Delfanti, Sara, De Angelis, Antonina, Muzio, Alberto, Zucali, Paolo Andrea, Allavena, Paola, Ceresoli, Giovanni Luca, Marchini, Sergio, Calabrese, Fiorella, D'Incalci, Maurizio, Grosso, Federica

“…Pleural mesothelioma (PM) is an aggressive tumor with few therapeutic options. Although patients with epithelioid PM (ePM) survive longer than non-epithelioid…”
Get full text

In Vitro and In Vivo Activity of Lucitanib in FGFR1/2 Amplified or Mutated Cancer Models by Guffanti, Federica, Chilà, Rosaria, Bello, Ezia, Zucchetti, Massimo, Zangarini, Monique, Ceriani, Laura, Ferrari, Mariella, Lupi, Monica, Jacquet-Bescond, Anne, Burbridge, Mike F, Pierrat, Marie-Jeanne, Damia, Giovanna

“…Abstract The fibroblast growth factor receptor (FGFR) pathway has been implicated both as an escape mechanism from anti-angiogenic therapy and as a driver…”
Get full text

Dynamic rendering of the heterogeneous cell response to anticancer treatments by Falcetta, Francesca, Lupi, Monica, Colombo, Valentina, Ubezio, Paolo

“…The antiproliferative response to anticancer treatment is the result of concurrent responses in all cell cycle phases, extending over several cell generations,…”
Get full text

Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia by Gianni’, Maurizio, Goracci, Laura, Schlaefli, Anna, Di Veroli, Alessandra, Kurosaki, Mami, Guarrera, Luca, Bolis, Marco, Foglia, Marika, Lupi, Monica, Tschan, Mario P., Cruciani, Gabriele, Terao, Mineko, Garattini, Enrico

“…The role played by lipids in the process of granulocytic differentiation activated by all-trans retinoic acid (ATRA) in Acute-Promyelocytic-Leukemia (APL)…”
Get full text

Tumor treating fields affect mesothelioma cell proliferation by exerting histotype-dependent cell cycle checkpoint activations and transcriptional modulations by Mannarino, Laura, Mirimao, Federica, Panini, Nicolò, Paracchini, Lara, Marchini, Sergio, Beltrame, Luca, Amodeo, Rosy, Grosso, Federica, Libener, Roberta, De Simone, Irene, Ceresoli, Giovanni L., Zucali, Paolo A., Lupi, Monica, D’Incalci, Maurizio

“…Although clinical antitumor activity of Tumor Treating Fields (TTFields) has been reported in malignant pleural mesothelioma (MPM) patients, the mechanisms…”
Get full text

Cellular and molecular determinants of all‐trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression by Centritto, Floriana, Paroni, Gabriela, Bolis, Marco, Garattini, Silvio Ken, Kurosaki, Mami, Barzago, Maria Monica, Zanetti, Adriana, Fisher, James Neil, Scott, Mark Francis, Pattini, Linda, Lupi, Monica, Ubezio, Paolo, Piccotti, Francesca, Zambelli, Alberto, Rizzo, Paola, Gianni', Maurizio, Fratelli, Maddalena, Terao, Mineko, Garattini, Enrico

“…Forty‐two cell lines recapitulating mammary carcinoma heterogeneity were profiled for all‐ trans retinoic acid (ATRA) sensitivity. Luminal and ER +…”
Get full text

Role of mitochondria and cardiolipins in growth inhibition of breast cancer cells by retinoic acid by Terao, Mineko, Goracci, Laura, Celestini, Valentina, Kurosaki, Mami, Bolis, Marco, Di Veroli, Alessandra, Vallerga, Arianna, Fratelli, Maddalena, Lupi, Monica, Corbelli, Alessandro, Fiordaliso, Fabio, Gianni, Maurizio, Paroni, Gabriela, Zanetti, Adriana, Cruciani, Gabriele, Garattini, Enrico

“…All-trans-retinoic-acid (ATRA) is a promising agent in the prevention/treatment of breast-cancer. There is growing evidence that reprogramming of cellular…”
Get full text

Glutaminase Inhibition on NSCLC Depends on Extracellular Alanine Exploitation by Caiola, Elisa, Colombo, Marika, Sestito, Giovanna, Lupi, Monica, Marabese, Mirko, Pastorelli, Roberta, Broggini, Massimo, Brunelli, Laura

“…Non-small-cell lung cancer (NSCLC) cell lines vary in their sensitivity to glutaminase inhibitors, so it is important to identify the metabolic assets…”
Get full text

Correction to: Role of mitochondria and cardiolipins in growth inhibition of breast cancer cells by retinoic acid by Terao, Mineko, Goracci, Laura, Celestini, Valentina, Kurosaki, Mami, Bolis, Marco, Di Veroli, Alessandra, Vallerga, Arianna, Fratelli, Maddalena, Lupi, Monica, Corbelli, Alessandro, Fiordaliso, Fabio, Gianni, Maurizio, Paroni, Gabriela, Zanetti, Adriana, Cruciani, Gabriele, Garattini, Enrico

“…In the original publication of this article [1], the images of Figs. 4 and 5 were exchanged and the legends of the two figures did not correspond due to a…”
Get full text

Trypsinogen 4 boosts tumor endothelial cells migration through proteolysis of tissue factor pathway inhibitor-2 by Ghilardi, Carmen, Silini, Antonietta, Figini, Sara, Anastasia, Alessia, Lupi, Monica, Fruscio, Robert, Giavazzi, Raffaella, Bani, Maria Rosa

“…Proteases contribute to cancer in many ways, including tumor vascularization and metastasis, and their pharmacological inhibition is a potential anticancer…”
Get full text

The molecular assembly of amyloid aβ controls its neurotoxicity and binding to cellular proteins by Manzoni, Claudia, Colombo, Laura, Bigini, Paolo, Diana, Valentina, Cagnotto, Alfredo, Messa, Massimo, Lupi, Monica, Bonetto, Valentina, Pignataro, Mauro, Airoldi, Cristina, Sironi, Erika, Williams, Alun, Salmona, Mario

“…Accumulation of β-sheet-rich peptide (Aβ) is strongly associated with Alzheimer's disease, characterized by reduction in synapse density, structural…”
Get full text

Low levels of ALS-linked Cu/Zn superoxide dismutase increase the production of reactive oxygen species and cause mitochondrial damage and death in motor neuron-like cells by Rizzardini, Milena, Mangolini, Alessandra, Lupi, Monica, Ubezio, Paolo, Bendotti, Caterina, Cantoni, Lavinia

“…Mutations of Cu/Zn superoxide dismutase (SOD1) are found in patients with familial amyotrophic lateral sclerosis (FALS). A cellular model of FALS was developed…”
Get full text

The Contribution of p53 in the Dynamics of Cell Cycle Response to DNA Damage Interpreted by a Mathematical Model by Lupi, Monica, Matera, Giada, Natoli, Claudia, Colombo, Valentina, Ubezio, Paolo

“…Despite numerous studies on the tumor suppressor p53, a complete picture of its role in cell arrest and killing in G1, S and G2M phases after drug treatment is…”
Get full text

Induction of miR-21 by Retinoic Acid in Estrogen Receptor-positive Breast Carcinoma Cells by Terao, Mineko, Fratelli, Maddalena, Kurosaki, Mami, Zanetti, Adriana, Guarnaccia, Valeria, Paroni, Gabriela, Tsykin, Anna, Lupi, Monica, Gianni, Maurizio, Goodall, Gregory J., Garattini, Enrico

“…Retinoids are promising agents for the treatment/prevention of breast carcinoma. We examined the role of microRNAs in mediating the effects of…”
Get full text

Interpreting cell cycle effects of drugs : the case of melphalan by LUPI, Monica, CAPPELLA, Paolo, MATERA, Giada, NATOLI, Claudia, UBEZIO, Paolo

“…Multiple effects usually occur in the cell cycle, during and after the exposure to a drug, while treated cells flowing through the cycle encounter G1, S and…”
Get full text