Search Results - "LUNN, R. M"
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XPD polymorphisms: effects on DNA repair proficiency
Published in Carcinogenesis (New York) (01-04-2000)“…XPD codes for a DNA helicase involved in transcription and nucleotide excision repair. Rare XPD mutations diminish nucleotide excision repair resulting in…”
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2
Risk of Bias Assessments and Evidence Syntheses for Observational Epidemiologic Studies of Environmental and Occupational Exposures: Strengths and Limitations
Published in Environmental health perspectives (01-09-2020)“…Increasingly, risk of bias tools are used to evaluate epidemiologic studies as part of evidence synthesis (evidence integration), often involving…”
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3
Polymorphisms of the DNA repair genes XPD (Lys751Gln) and XRCC1 (Arg399Gln and Arg194Trp) : relationship to breast cancer risk and familial predisposition to breast cancer
Published in Breast cancer research and treatment (2006)“…Family history is a risk factor for breast cancer and could be due to shared environmental factors or polymorphisms of cancer susceptibility genes. Deficient…”
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4
DNA Repair Gene XRCC1 Polymorphisms, Smoking, and Bladder Cancer Risk
Published in Cancer epidemiology, biomarkers & prevention (01-02-2001)“…Bladder cancer is the sixth most common cancer in the United States. The main identified risk factor is cigarette smoking, which is estimated to contribute to…”
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5
Prostate cancer risk and polymorphism in 17 hydroxylase (CYP17) and steroid reductase (SRD5A2)
Published in Carcinogenesis (New York) (01-09-1999)“…Prostate cancer is the most common malignancy in males and is the second most common cause of cancer mortality in American men. Polymorphisms have been…”
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6
p53 mutations, chronic hepatitis B virus infection, and aflatoxin exposure in hepatocellular carcinoma in Taiwan
Published in Cancer research (Chicago, Ill.) (15-08-1997)“…Recent studies have implicated aflatoxin B1 (AFB1) exposure as an etiological agent in hepatocellular carcinoma (HCC) and suggested an interaction with chronic…”
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7
XRCC1 polymorphisms : Effects on aflatoxin B1-DNA adducts and glycophorin A variant frequency
Published in Cancer research (Chicago, Ill.) (01-06-1999)“…Hereditary genetic defects in DNA repair lead to increased risk of cancer. Polymorphisms in several DNA repair genes have been identified; however, the impact…”
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8
Polymorphisms in the DNA Repair Gene XRCC1 and Breast Cancer
Published in Cancer epidemiology, biomarkers & prevention (01-03-2001)“…X-ray repair cross complementing group 1 ( XRCC1 ) encodes a protein involved in base excision repair. We examined the association of polymorphisms in XRCC1…”
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9
No association between the XPD (Lys751G1n) polymorphism or the XRCC3 (Thr241Met) polymorphism and lung cancer risk
Published in Cancer epidemiology, biomarkers & prevention (01-08-2001)Get full text
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10
Growth inhibition induced by Ro 31-8220 and calphostin C in human glioblastoma cell lines is associated with apoptosis and inhibition of CDC2 kinase
Published in Anticancer research (01-09-1998)“…Protein kinase C (PKC) is a central component in signal transduction and growth control and might be an appropriate target for the chemotherapy of human brain…”
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Correlation between the anticellular and DNA fragmenting activities of tumor necrosis factor
Published in Cancer research (Chicago, Ill.) (01-11-1988)“…The treatment of cells sensitive to the anticellular effect of tumor necrosis factor (TNF) with TNF results in a degradation of their cellular DNA into DNA…”
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12
Tumor necrosis factor and IFN induce a common set of proteins
Published in The Journal of immunology (1950) (15-08-1988)“…The treatment of cells with TNF or IFN results in the development of an antiviral state and in the induction of a common set of proteins with m.w. of 80,000,…”
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13
Spinal muscular atrophy
Published in The Lancet (British edition) (21-06-2008)“…Summary Spinal muscular atrophy is an autosomal recessive neurodegenerative disease characterised by degeneration of spinal cord motor neurons, atrophy of…”
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14
Induction of proteins in interferon-alpha- and interferon-gamma-treated polymorphonuclear leukocytes
Published in Journal of leukocyte biology (01-05-1989)“…Interferon-gamma (IFN-gamma) treatment of polymorphonuclear leukocytes (PMNs) results in an activation of their functions. Studying the IFN responsiveness of…”
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15
Production of a monoclonal antibody directed against an interferon-induced 56,000-dalton protein and its use in the study of this protein
Published in Journal of Virology (01-06-1988)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The development of antibody to the interferon-induced indoleamine 2,3-dioxygenase and the study of the regulation of its synthesis
Published in Journal of interferon research (01-10-1988)“…Interferon (IFN) treatment of cells induces the synthesis of several new proteins. Antibody to the IFN-induced 42,000 dalton protein has been prepared and used…”
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Indoprofen Upregulates the Survival Motor Neuron Protein through a Cyclooxygenase-Independent Mechanism
Published in Chemistry & biology (01-11-2004)“…Most patients with the pediatric neurodegenerative disease spinal muscular atrophy have a homozygous deletion of the survival motor neuron 1 ( SMN1) gene, but…”
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Fragmentation of cellular DNA is a nonspecific indicator of responsiveness to tumor necrosis factor
Published in Journal of biological response modifiers (01-10-1989)“…Tumor necrosis factor (TNF) or lymphotoxin (LT) treatment of cells sensitive to the anticellular action of TNF results in the degradation of their cellular DNA…”
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Pathways to parenthood among transgender men and gender diverse people assigned female or intersex at birth in the United States: analysis of a Cross-Sectional 2019 SurveyAJOG Global Reports at a Glance
Published in AJOG global reports (01-08-2024)“…Objective: To assess pathways to parenthood, pregnancy outcomes, future pregnancy desire, and fertility counseling experiences among a cross-sectional sample…”
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Family building and pregnancy experiences of cisgender sexual minority womenAJOG Global Reports at a Glance
Published in AJOG global reports (01-02-2024)“…BACKGROUND: Although 10% to 20% of cisgender women aged 18 to 40 years have a sexual minority identity (eg, bisexual, lesbian, and queer), there is limited…”
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