Search Results - "LUNIN, Vladimir V"
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Structural biology of human H3K9 methyltransferases
Published in PloS one (11-01-2010)“…SET domain methyltransferases deposit methyl marks on specific histone tail lysine residues and play a major role in epigenetic regulation of gene…”
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2
Engineering enhanced cellobiohydrolase activity
Published in Nature communications (22-03-2018)“…Glycoside Hydrolase Family 7 cellobiohydrolases (GH7 CBHs) catalyze cellulose depolymerization in cellulolytic eukaryotes, making them key discovery and…”
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Structural, mutagenic and in silico studies of xyloglucan fucosylation in Arabidopsis thaliana suggest a water‐mediated mechanism
Published in The Plant journal : for cell and molecular biology (01-09-2017)“…Summary The mechanistic underpinnings of the complex process of plant polysaccharide biosynthesis are poorly understood, largely because of the resistance of…”
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Streamlining heterologous expression of top carbonic anhydrases in Escherichia coli: bioinformatic and experimental approaches
Published in Microbial cell factories (02-07-2024)“…Carbonic anhydrase (CA) enzymes facilitate the reversible hydration of CO to bicarbonate ions and protons. Identifying efficient and robust CAs and expressing…”
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Characterization of the Biomass Degrading Enzyme GuxA from Acidothermus cellulolyticus
Published in International journal of molecular sciences (28-05-2022)“…Microbial conversion of biomass relies on a complex combination of enzyme systems promoting synergy to overcome biomass recalcitrance. Some thermophilic…”
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Cel48A from Thermobifida fusca: Structure and site directed mutagenesis of key residues
Published in Biotechnology and bioengineering (01-04-2014)“…ABSTRACT Lignocellulosic biomass is a potential source of sustainable transportation fuels, but efficient enzymatic saccharification of cellulose is a key…”
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Crystal structure of the CorA Mg2+ transporter
Published in Nature (London) (06-04-2006)“…The magnesium ion, Mg2+, is essential for myriad biochemical processes and remains the only major biological ion whose transport mechanisms remain unknown. The…”
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Towards an Understanding of Enhanced Biomass Digestibility by In Planta Expression of a Family 5 Glycoside Hydrolase
Published in Scientific reports (29-06-2017)“…In planta expression of a thermophilic endoglucanase (AcCel5A) reduces recalcitrance by creating voids and other irregularities in cell walls of Arabidopsis…”
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The Unique Binding Mode of Cellulosomal CBM4 from Clostridium thermocellum Cellobiohydrolase A
Published in Journal of molecular biology (17-09-2010)“…The crystal structure of the carbohydrate-binding module (CBM) 4 Ig fused domain from the cellulosomal cellulase cellobiohydrolase A (CbhA) of Clostridium…”
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10
Glyoxylate and Pyruvate Are Antagonistic Effectors of the Escherichia coli IclR Transcriptional Regulator
Published in The Journal of biological chemistry (01-06-2007)“…The Escherichia coli isocitrate lyase regulator (IclR) regulates the expression of the glyoxylate bypass operon (aceBAK). Founding member of a large family of…”
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Structural and Biochemical Characterization of the Type II Fructose-1,6-bisphosphatase GlpX from Escherichia coli
Published in The Journal of biological chemistry (06-02-2009)“…Gluconeogenesis is an important metabolic pathway, which produces glucose from noncarbohydrate precursors such as organic acids, fatty acids, amino acids, or…”
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Structural and Functional Characterization of PseC, an Aminotransferase Involved in the Biosynthesis of Pseudaminic Acid, an Essential Flagellar Modification in Helicobacter pylori
Published in The Journal of biological chemistry (31-03-2006)“…Helicobacter pylori flagellin is heavily glycosylated with the novel sialic acid-like nonulosonate, pseudaminic acid (Pse). The glycosylation process is…”
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Crystal Structures of Escherichia coli ATP-Dependent Glucokinase and Its Complex with Glucose
Published in Journal of Bacteriology (01-10-2004)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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High-resolution Crystal Structure of Arthrobacter aurescens Chondroitin AC Lyase: An Enzyme–Substrate Complex Defines the Catalytic Mechanism
Published in Journal of molecular biology (19-03-2004)“…Chondroitin lyases (EC 4.2.2.4 and EC 4.2.2.5) are glycosaminoglycan-degrading enzymes that act as eliminases. Chondroitin lyase AC from Arthrobacter aurescens…”
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Revealing Nature's Cellulase Diversity: The Digestion Mechanism of Caldicellulosiruptor bescii CelA
Published in Science (American Association for the Advancement of Science) (20-12-2013)“…Most fungi and bacteria degrade plant cell walls by secreting free, complementary enzymes that hydrolyze cellulose; however, some bacteria use large enzymatic…”
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Essential Roles of Zinc Ligation and Enzyme Dimerization for Catalysis in the Aminoacylase-1/M20 Family
Published in The Journal of biological chemistry (07-11-2003)“…Members of the aminoacylase-1 (Acy1)/M20 family of aminoacylases and exopeptidases exist as either monomers or homodimers. They contain a zinc-binding domain…”
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The Crystal Structure of CREG, a Secreted Glycoprotein Involved in Cellular Growth and Differentiation
Published in Proceedings of the National Academy of Sciences - PNAS (20-12-2005)“…The cellular repressor of E1A-stimulated genes (CREG) is a secreted glycoprotein that inhibits proliferation and enhances differentiation of human embryonal…”
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Molecular Mechanism of Polysaccharide Acetylation by the Arabidopsis Xylan O-acetyltransferase XOAT1
Published in The Plant cell (01-07-2020)“…Structural and biochemical analysis of xylan O-acetyltransferase 1 (XOAT1) show that XOAT1 catalyzes xylan acetylation through formation of an acyl-enzyme…”
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Structure of a Thermobifida fusca lytic polysaccharide monooxygenase and mutagenesis of key residues
Published in Biotechnology for biofuels (30-11-2017)“…Auxiliary activity (AA) enzymes are produced by numerous bacterial and fungal species to assist in the degradation of biomass. These enzymes are abundant but…”
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Crystallography of Metabolic Enzymes
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2020)“…The metabolic enzymes like any enzymes generally display globular architecture where secondary structure elements and interactions between them preserve the…”
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