Search Results - "LUNELL, Erik"

Pharmacokinetic Comparison of a Novel Non-tobacco-Based Nicotine Pouch (ZYN) With Conventional, Tobacco-Based Swedish Snus and American Moist Snuff by Lunell, Erik, Fagerström, Karl, Hughes, John, Pendrill, Robert

“…The single-dose pharmacokinetics (PK) of a novel, non-tobacco-based nicotine pouch, ZYN, 3 and 6 mg, were compared with 8 mg General snus (part 1) and ZYN 8 mg…”
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Exposure to high ambient temperature increases absorption and plasma concentrations of transdermal nicotine by Vanakoski, J, Seppälä, T, Sievi, E, Lunell, E

“…Absorption and plasma concentrations of transdermally delivered drugs may be increased during heat exposure. We studied the effects of short-term heat exposure…”
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Nicotine Delivery and Subjective Effects of Swedish Portion Snus Compared With 4 mg Nicotine Polacrilex Chewing Gum by Lunell, Erik, Curvall, Margareta

“…Introduction: Snus availability has been claimed to have contributed to the low rates of smoking among Swedish men and made possible the transfer to a less…”
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Steady-state nicotine plasma levels following use of four different types of Swedish snus compared with 2-mg Nicorette chewing gum: A crossover study by Lunell, Erik, Lunell, Marianne

“…The present study evaluated nicotine plasma levels achieved following 1 day's regular use of four commonly used brands of Swedish portion snus and 2-mg…”
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Pharmacokinetics of nicotine in healthy elderly people by Molander, Lars, Hansson, Anna, Lunell, Erik

“…Background Mortality hazards of smoking extend well into later life; this suggests that smoking cessation will continue to improve life expectancy in older…”
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The nicotine inhaler: Clinical pharmacokinetics and comparison with other nicotine treatments by SCHNEIDER, Nina G, OLMSTEAD, Richard E, FRANZON, Mikael A, LUNELL, Erik

“…Nicotine inhaled in smoke is the most rapid form of delivery of the drug. With smoking, arterial boli and high venous blood nicotine concentrations are…”
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Aiding reduction of smoking with nicotine replacement medications: hope for the recalcitrant smoker? by Fagerström, K O, Tejding, R, Westin, A, Lunell, E

“…OBJECTIVE: To assess the effect of the various nicotine replacement therapies (NRT) on smoking reduction. DESIGN: During an initial sampling week, the subjects…”
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Enprofylline kinetics in healthy subjects after single doses by Borgå, O, Andersson, K E, Edholm, L E, Fagerström, P O, Lunell, E, Persson, C G

“…The kinetics of enprofylline, a novel antiasthmatic xanthine derivative, were studied. Eight healthy subjects received three different single enprofylline…”
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Pharmacokinetics of nicotine in kidney failure by Molander, Lars, Hansson, Anna, Lunell, Erik, Alainentalo, Lisbeth, Hoffmann, Mikael, Larsson, Rutger

“…Background Smoking is an important risk factor for cardiovascular and cerebrovascular complications in patients with chronic kidney failure. Very high plasma…”
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Electroencephalographic effects of intravenous nicotine : a dose-response study by LINDGREN, M, MOLANDER, L, VERBAAN, C, LUNELL, E, ROSEN, I

“…It has often been demonstrated that both tobacco abstinence and nicotine have effects on the EEG power spectrum and components of the event-related potentials…”
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Clinical pharmacokinetics of nasal nicotine delivery : A review and comparison to other nicotine systems by SCHNEIDER, N. G, LUNELL, E, OLMSTEAD, R. E, FAGERSTRÖM, K.-O

“…Rapid drug delivery (arterial "boli') and high drug concentrations occur with nicotine inhaled in smoke. These are believed to be key elements in producing…”
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Reduction of tobacco withdrawal symptoms with a sublingual nicotine tablet: a placebo controlled study by Molander, Lars, Lunell, Erik, Fagerström, Karl Olov

“…Many smokers are unable to use gum as a cessation aid due to fillings, bridgework and dyspepsia or they reject it for esthetic reasons. The nicotine sublingual…”
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Nicotine deposition and body distribution from a nicotine inhaler and a cigarette studied with positron emission tomography by Lunell, E, Bergström, M, Antoni, G, Långström, B, Nordberg, A

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Dose released and absolute bioavailability of nicotine from a nicotine vapor inhaler by Molander, L, Lunell, E, Andersson, S B, Kuylenstierna, F

“…In an open, randomized, three-way crossover study, 14 healthy smokers used one type of nicotine vapor inhaler intensely for 20 minutes every hour for 11 hours…”
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Biological availability and pharmacokinetics of tinidazole after single and repeated doses by Vinge, E, Andersson, K E, Ando, G, Lunell, E

“…Tinidazole was administered to healthy volunteers and serum concentrations were measured following single oral and intravenous doses and after repeated dosage…”
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Acute Effects of Nicotine Infusion on Platelets in Nicotine Users with Normal and Impaired Renal Function by Whiss, Per A., Lundahl, Tom H., Bengtsson, Torbjörn, Lindahl, Tomas L., Lunell, Erik, Larsson, Rutger

“…The role of platelets in cardiovascular disease associated with smoking is becoming more established, but the effects of nicotine on platelets are unclear…”
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Regional deposition of inhaled 11C-nicotine vapor in the human airway as visualized by positron emission tomography by Bergström, M, Nordberg, A, Lunell, E, Antoni, G, Långström, B

“…The deposition of 11C-nicotine in the respiratory tract from a nicotine vapor inhaler was studied by means of positron emission tomography (PET) in an…”
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