Search Results - "LUNDHOLM, Marie"

Prostate tumor-derived exosomes down-regulate NKG2D expression on natural killer cells and CD8+ T cells: mechanism of immune evasion by Lundholm, Marie, Schröder, Mona, Nagaeva, Olga, Baranov, Vladimir, Widmark, Anders, Mincheva-Nilsson, Lucia, Wikström, Pernilla

“…Tumor-derived exosomes, which are nanometer-sized extracellular vesicles of endosomal origin, have emerged as promoters of tumor immune evasion but their role…”
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Tumor Cell-Derived Exosomes from the Prostate Cancer Cell Line TRAMP-C1 Impair Osteoclast Formation and Differentiation by Karlsson, Terese, Lundholm, Marie, Widmark, Anders, Persson, Emma

“…Skeletal metastatic disease is a deleterious consequence of dissemination of tumor cells from numerous primary sites, such as prostate, lung and breast…”
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Rat prostate tumors induce DNA synthesis in remote organs by Halin Bergström, Sofia, Lundholm, Marie, Nordstrand, Annika, Bergh, Anders

“…Advanced cancers induce systemic responses. However, if such systemic changes occur already when aggressive tumors are small, have not been thoroughly…”
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Secreted Factors from Colorectal and Prostate Cancer Cells Skew the Immune Response in Opposite Directions by Lundholm, Marie, Hägglöf, Christina, Wikberg, Maria L., Stattin, Pär, Egevad, Lars, Bergh, Anders, Wikström, Pernilla, Palmqvist, Richard, Edin, Sofia

“…Macrophage infiltration has been associated with an improved prognosis in patients with colorectal cancer (CRC), but a poor prognosis in prostate cancer (PC)…”
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Highly aggressive rat prostate tumors rapidly precondition regional lymph nodes for subsequent metastatic growth by Strömvall, Kerstin, Lundholm, Marie, Thysell, Elin, Bergh, Anders, Halin Bergström, Sofia

“…The aim of this study was to examine in what ways MatLyLu (MLL) rat prostate tumors with high metastatic capacity influence regional lymph nodes prior to…”
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Marked response to cabazitaxel in prostate cancer xenografts expressing androgen receptor variant 7 and reversion of acquired resistance by anti‐androgens by Ylitalo, Erik Bovinder, Thysell, Elin, Thellenberg‐Karlsson, Camilla, Lundholm, Marie, Widmark, Anders, Bergh, Anders, Josefsson, Andreas, Brattsand, Maria, Wikström, Pernilla

“…Background Taxane treatment may be a suitable therapeutic option for patients with castration‐resistant prostate cancer and high expression of constitutively…”
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Clinical and biological relevance of the transcriptomic‐based prostate cancer metastasis subtypes MetA‐C by Thysell, Elin, Köhn, Linda, Semenas, Julius, Järemo, Helena, Freyhult, Eva, Lundholm, Marie, Thellenberg Karlsson, Camilla, Damber, Jan‐Erik, Widmark, Anders, Crnalic, Sead, Josefsson, Andreas, Welén, Karin, Nilsson, Rolf J. A., Bergh, Anders, Wikström, Pernilla

“…To improve treatment of metastatic prostate cancer, the biology of metastases needs to be understood. We recently described three subtypes of prostate cancer…”
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DNA Content in Extracellular Vesicles Isolated from Porcine Coronary Venous Blood Directly after Myocardial Ischemic Preconditioning by Svennerholm, Kristina, Rodsand, Pouria, Hellman, Urban, Waldenström, Anders, Lundholm, Marie, Ahrén, Dag, Biber, Björn, Ronquist, Gunnar, Haney, Michael

“…Extracellular vesicles (EV) are nano-sized membranous structures released from most cells. They have the capacity to carry bioactive molecules and gene…”
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A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis by Fransén-Pettersson, Nina, Duarte, Nadia, Nilsson, Julia, Lundholm, Marie, Mayans, Sofia, Larefalk, Åsa, Hannibal, Tine D, Hansen, Lisbeth, Schmidt-Christensen, Anja, Ivars, Fredrik, Cardell, Susanna, Palmqvist, Richard, Rozell, Björn, Holmberg, Dan

“…Here we characterize a new animal model that spontaneously develops chronic inflammation and fibrosis in multiple organs, the non-obese diabetic inflammation…”
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Prevention of Diabetes in Nonobese Diabetic Mice Mediated by CD1d-Restricted Nonclassical NKT Cells by Duarte, Nadia, Stenstrom, Martin, Campino, Susana, Bergman, Marie-Louise, Lundholm, Marie, Holmberg, Dan, Cardell, Susanna L

“…A role for regulatory lymphocytes has been demonstrated in the pathogenesis of type 1 diabetes in the NOD mouse but the nature of these cells is debated…”
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Myocardial ischemic preconditioning in a porcine model leads to rapid changes in cardiac extracellular vesicle messenger RNA content by Svennerholm, Kristina, Rodsand, Pouria, Hellman, Urban, Lundholm, Marie, Waldenström, Anders, Biber, Björn, Ronquist, Gunnar, Haney, Michael

“…Extracellular vesicles (EVs) are thought to exert protective effects after ischemic and remote ischemic preconditioning. It is not well understood which EV…”
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Idd6.2 diabetes susceptibility region controls defective expression of the Lrmp gene in nonobese diabetic (NOD) mice by Duarte, Nádia, Lundholm, Marie, Holmberg, Dan

“…The identification of genes mediating susceptibility to type 1 diabetes (T1D) remains a challenging task. Using a positional cloning approach based on the…”
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Defective Induction of CTLA-4 in the NOD Mouse Is Controlled by the NOD Allele of Idd3/IL-2 and a Novel Locus (Ctex) Telomeric on Chromosome 1 by LUNDHOLM, Marie, MOTTA, Vinicius, LÖFGREN-BURSTRÖM, Anna, DUARTE, Nadia, BERGMAN, Marie-Louise, MAYANS, Sofia, HOLMBERG, Dan

“…Defective Induction of CTLA-4 in the NOD Mouse Is Controlled by the NOD Allele of Idd3/IL-2 and a Novel Locus ( Ctex ) Telomeric on Chromosome 1 Marie Lundholm…”
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M2 macrophages and regulatory T cells in lethal prostate cancer by Erlandsson, Ann, Carlsson, Jessica, Lundholm, Marie, Fält, Anna, Andersson, Sven‐Olof, Andrén, Ove, Davidsson, Sabina

“…Background Prostate cancer (PCa) is one of the most frequently diagnosed cancers in the world. Emerging evidence suggests that inflammatory cells such as M2…”
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Diabetes Protection and Restoration of Thymocyte Apoptosis in NOD Idd6 Congenic Strains by BERGMAN, Marie-Louise, DUARTE, Nadia, CAMPINO, Susana, LUNDHOLM, Marie, MOTTA, Vinicius, LEJON, Kristina, PENHA-GONCALVES, Carlos, HOLMBERG, Dan

“…Diabetes Protection and Restoration of Thymocyte Apoptosis in NOD Idd6 Congenic Strains Marie-Louise Bergman 1 , Nadia Duarte 1 2 , Susana Campino 2 , Marie…”
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CTLA-4 (CD152) and its involvement in autoimmune disease by Holmberg, Dan, Cilio, Corrado M., Lundholm, Marie, Motta, Vinicius

“…Autoimmune diseases (AID) are inherited as complex genetic diseases. Different Autoimmune diseases have been found to cluster in families and are believed to…”
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Subgroups of Castration-resistant Prostate Cancer Bone Metastases Defined Through an Inverse Relationship Between Androgen Receptor Activity and Immune Response by Ylitalo, Erik Bovinder, Thysell, Elin, Jernberg, Emma, Lundholm, Marie, Crnalic, Sead, Egevad, Lars, Stattin, Pär, Widmark, Anders, Bergh, Anders, Wikström, Pernilla

“…Abstract Background Novel therapies for men with castration-resistant prostate cancer (CRPC) are needed, particularly for cancers not driven by androgen…”
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Platelets harbor prostate cancer biomarkers and the ability to predict therapeutic response to abiraterone in castration resistant patients by Tjon‐Kon‐Fat, Lee‐Ann, Lundholm, Marie, Schröder, Mona, Wurdinger, Thomas, Thellenberg‐Karlsson, Camilla, Widmark, Anders, Wikström, Pernilla, Nilsson, Rolf Jonas Andreas

“…Background Novel therapies for castration resistant prostate cancer (CRPC) have been introduced in the clinic with possibilities for individualized treatment…”
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High‐grade tumours promote growth of other less‐malignant tumours in the same prostate by Halin Bergström, Sofia, Rudolfsson, Stina, Lundholm, Marie, Josefsson, Andreas, Wikström, Pernilla, Bergh, Anders

“…Prostate cancer is a multifocal disease, but if and how individual prostate tumours influence each other is largely unknown. We therefore explored signs of…”
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Abstract B08: Tumor-educated platelets for early prostate cancer diagnosis, and therapy stratification in patients with metastasized castration resistant prostate cancer by Tjon-Kon-Fat, Lee-Ann, Köhn, Linda, Best, Myron, Lundholm, Marie, Wurdinger, Thomas, Widmark, Anders, Thellenberg-Karlsson, Camilla, Wikström, Pernilla, Nilsson, Jonas

“…One in every ten men diagnosed with prostate cancer will have metastases at some point, causing the high mortality of prostate cancer. Only earlier diagnosis…”
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