Search Results - "LUNDBERG, M"

Explaining a series of models by propagating Shapley values by Chen, Hugh, Lundberg, Scott M., Lee, Su-In

“…Local feature attribution methods are increasingly used to explain complex machine learning models. However, current methods are limited because they are…”
Get full text

The Potential Cardiovascular Benefits of Physical Exercise in Early Onset Psychosis and Bipolar Disorder by Bohman, H C, Lundberg, M

“…IntroductionEarly onset psychosis (EOP) and bipolar disorder (EOBP), occurring before the age of 18, have been linked to early signs of atherosclerosis and an…”
Get full text

A machine learning approach to integrate big data for precision medicine in acute myeloid leukemia by Lee, Su-In, Celik, Safiye, Logsdon, Benjamin A., Lundberg, Scott M., Martins, Timothy J., Oehler, Vivian G., Estey, Elihu H., Miller, Chris P., Chien, Sylvia, Dai, Jin, Saxena, Akanksha, Blau, C. Anthony, Becker, Pamela S.

“…Cancers that appear pathologically similar often respond differently to the same drug regimens. Methods to better match patients to drugs are in high demand…”
Get full text

Explainable machine-learning predictions for the prevention of hypoxaemia during surgery by Lundberg, Scott M., Nair, Bala, Vavilala, Monica S., Horibe, Mayumi, Eisses, Michael J., Adams, Trevor, Liston, David E., Low, Daniel King-Wai, Newman, Shu-Fang, Kim, Jerry, Lee, Su-In

“…Although anaesthesiologists strive to avoid hypoxaemia during surgery, reliably predicting future intraoperative hypoxaemia is not possible at present. Here,…”
Get full text

Parental age and the risk of autism spectrum disorders: findings from a Swedish population-based cohort by IDRING, Selma, MAGNUSSON, Cecilia, LUNDBERG, Michael, EK, Mats, RAI, Dheeraj, SVENSSON, Anna C, DALMAN, Christina, KARLSSON, Håkan, LEE, Brian K

“…The objectives of this study were to examine the independent and dependent associations of maternal and paternal age and risk of offspring autism spectrum…”
Get full text

Bioactive adrenomedullin in sepsis patients in the emergency department is associated with mortality, organ failure and admission to intensive care by Lundberg, Oscar H M, Rosenqvist, Mari, Bronton, Kevin, Schulte, Janin, Friberg, Hans, Melander, Olle

“…Adrenomedullin is a vasoactive hormone with potentially prognostic and therapeutic value, which mainly has been investigated in intensive care unit (ICU)…”
Get full text

Circulating bioactive adrenomedullin as a marker of sepsis, septic shock and critical illness by Lundberg, Oscar H. M., Lengquist, Maria, Spångfors, Martin, Annborn, Martin, Bergmann, Deborah, Schulte, Janin, Levin, Helena, Melander, Olle, Frigyesi, Attila, Friberg, Hans

“…Abstract Background Biomarkers can be of help to understand critical illness and to identify and stratify sepsis. Adrenomedullin is a vasoactive hormone, with…”
Get full text

Rapid Aldosterone-Mediated Signaling in the DCT Increases Activity of the Thiazide-Sensitive NaCl Cotransporter by Cheng, Lei, Poulsen, Søren Brandt, Wu, Qi, Esteva-Font, Cristina, Olesen, Emma T B, Peng, Li, Olde, Björn, Leeb-Lundberg, L M Fredrik, Pisitkun, Trairak, Rieg, Timo, Dimke, Henrik, Fenton, Robert A

“…The NaCl cotransporter NCC in the kidney distal convoluted tubule (DCT) regulates urinary NaCl excretion and BP. Aldosterone increases NaCl reabsorption NCC…”
Get full text

Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) for advanced pancreatic and periampullary adenocarcinoma by Thosani, Nirav, Cen, Putao, Rowe, Julie, Guha, Sushovan, Bailey-Lundberg, Jennifer M., Bhakta, Dimpal, Patil, Prithvi, Wray, Curtis J.

“…Long term prognosis and 5-year survival for pancreatic adenocarcinoma (PDAC) remains suboptimal. Endoscopic ultrasound (EUS) guided RFA (EUS-RFA) is an…”
Get full text

Breast cancer hypoxia in relation to prognosis and benefit from radiotherapy after breast-conserving surgery in a large, randomised trial with long-term follow-up by Tutzauer, Julia, Sjöström, Martin, Holmberg, Erik, Karlsson, Per, Killander, Fredrika, Leeb-Lundberg, L. M. Fredrik, Malmström, Per, Niméus, Emma, Fernö, Mårten, Jögi, Annika

“…Background Breast-conserving surgery followed by radiotherapy is part of standard treatment for early-stage breast cancer. Hypoxia is common in cancer and may…”
Get full text

X-Ray Absorption Spectrum of the N2+ Molecular Ion by Lindblad, R, Kjellsson, L, Couto, R C, Timm, M, Bülow, C, Zamudio-Bayer, V, Lundberg, M, von Issendorff, B, Lau, J T, Sorensen, SL, Carravetta, V, Ågren, H, Rubensson, J-E

“…The x-ray absorption spectrum of N2+ in the K-edge region has been measured by irradiation of ions stored in a cryogenic radio frequency ion trap with…”
Get full text

Plasma membrane expression of G protein-coupled estrogen receptor (GPER)/G protein-coupled receptor 30 (GPR30) is associated with worse outcome in metachronous contralateral breast cancer by Tutzauer, Julia, Sjöström, Martin, Bendahl, Pär-Ola, Rydén, Lisa, Fernö, Mårten, Leeb-Lundberg, L M Fredrik, Alkner, Sara

“…G protein-coupled estrogen receptor (GPER), or G protein-coupled receptor 30 (GPR30), is reported to mediate non-genomic estrogen signaling. GPR30 associates…”
Get full text

Person-centred care in the context of higher education - a discourse analysis based on interviews with programme directors by Jonnergård, A, Björkman, I, Forsgren, E, Feldthusen, C, Lundberg, M, Wallengren, C

“…As person centred care (PCC) is being implemented globally, higher educational institutions (HEI) have begun to play a crucial part in enabling this…”
Get full text

CD73‐generated extracellular adenosine promotes resolution of neutrophil‐mediated tissue injury and restrains metaplasia in pancreatitis by O'Brien, Baylee J., Faraoni, Erika Y., Strickland, Lincoln N., Ma, Zhibo, Mota, Victoria, Mota, Samantha, Chen, Xuebo, Mills, Tingting, Eltzschig, Holger K., DelGiorno, Kathleen E., Bailey‐Lundberg, Jennifer M.

“…Pancreatitis is currently the leading cause of gastrointestinal hospitalizations in the US. This condition occurs in response to abdominal injury, gallstones,…”
Get full text

The tryptophan metabolite 3-hydroxyanthranilic acid lowers plasma lipids and decreases atherosclerosis in hypercholesterolaemic mice by LEI ZHANG, OVCHINNIKOVA, Olga, JONSSON, Andreas, LUNDBERG, Anna M, BERG, Martin, HANSSON, Göran K, KETELHUTH, Daniel F. J

“…Cardiovascular disease is the most common cause of death in the world and atherosclerosis, an inflammatory process in the vessel wall, accounts for the…”
Get full text

Kras mutation rate precisely orchestrates ductal derived pancreatic intraepithelial neoplasia and pancreatic cancer by Singh, Kanchan, Pruski, Melissa, Bland, Rachael, Younes, Mamoun, Guha, Sushovan, Thosani, Nirav, Maitra, Anirban, Cash, Brooks D., McAllister, Florencia, Logsdon, Craig D., Chang, Jeffrey T., Bailey-Lundberg, Jennifer M.

“…Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related death in the United States. Despite the high prevalence of Kras mutations…”
Get full text

Deletion of the G Protein-Coupled Receptor 30 Impairs Glucose Tolerance, Reduces Bone Growth, Increases Blood Pressure, and Eliminates Estradiol-Stimulated Insulin Release in Female Mice by Mårtensson, Ulrika E. A, Salehi, S. Albert, Windahl, Sara, Gomez, Maria F, Swärd, Karl, Daszkiewicz-Nilsson, Joanna, Wendt, Anna, Andersson, Niklas, Hellstrand, Per, Grände, Per-Olof, Owman, Christer, Rosen, Clifford J, Adamo, Martin L, Lundquist, Ingmar, Rorsman, Patrik, Nilsson, Bengt-Olof, Ohlsson, Claes, Olde, Björn, Leeb-Lundberg, L. M. Fredrik

“…In vitro studies suggest that the G protein-coupled receptor (GPR) 30 is a functional estrogen receptor. However, the physiological role of GPR30 in vivo is…”
Get full text

Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis by Lundberg, Anna M, Ketelhuth, Daniel F J, Johansson, Maria E, Gerdes, Norbert, Liu, Sang, Yamamoto, Masahiro, Akira, Shizuo, Hansson, Göran K

“…Members of the Toll-like receptor (TLR) family initiate innate immune responses and were recently shown to play a role in atherosclerosis. However, the…”
Get full text

Byproduct-based concentrates in Swedish dairy cow diets - evaluation of environmental impact and feed costs by Lindberg, M., Henriksson, M., Bååth Jacobsson, S., Berglund Lundberg, M.

“…This study compared use of byproduct-based concentrates and a control feed based on cereal grains and soybean meal in dairy cow diets and evaluated effects on…”
Get full text

High mobility group box protein 1 (HMGB1)-partner molecule complexes enhance cytokine production by signaling through the partner molecule receptor by Hreggvidsdóttir, Hulda Sigridur, Lundberg, Anna M, Aveberger, Ann-Charlotte, Klevenvall, Lena, Andersson, Ulf, Harris, Helena Erlandsson

“…The nuclear protein high mobility group box protein 1 (HMGB1) promotes inflammation upon extracellular release. HMGB1 induces proinflammatory cytokine…”
Get full text