Search Results - "LUKYANOV, Konstantin A"

Photoinduced Chemistry in Fluorescent Proteins: Curse or Blessing? by Acharya, Atanu, Bogdanov, Alexey M, Grigorenko, Bella L, Bravaya, Ksenia B, Nemukhin, Alexander V, Lukyanov, Konstantin A, Krylov, Anna I

“…Photoinduced reactions play an important role in the photocycle of fluorescent proteins from the green fluorescent protein (GFP) family. Among such processes…”
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Studying SARS-CoV-2 with Fluorescence Microscopy by Putlyaeva, Lidia V., Lukyanov, Konstantin A.

“…The COVID-19 pandemic caused by SARS-CoV-2 coronavirus deeply affected the world community. It gave a strong impetus to the development of not only approaches…”
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Fast reversibly photoswitching red fluorescent proteins for live-cell RESOLFT nanoscopy by Pennacchietti, Francesca, Serebrovskaya, Ekaterina O., Faro, Aline R., Shemyakina, Irina I., Bozhanova, Nina G., Kotlobay, Alexey A., Gurskaya, Nadya G., Bodén, Andreas, Dreier, Jes, Chudakov, Dmitry M., Lukyanov, Konstantin A., Verkhusha, Vladislav V., Mishin, Alexander S., Testa, Ilaria

“…Reversibly photoswitchable fluorescent proteins (rsFPs) are gaining popularity as tags for optical nanoscopy because they make it possible to image with lower…”
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Tracking intracellular protein movements using photoswitchable fluorescent proteins PS-CFP2 and Dendra2 by Lukyanov, Konstantin A, Chudakov, Dmitriy M, Lukyanov, Sergey

“…A number of photoactivatable GFP-like fluorescent proteins (PAFPs) have been reported whose fluorescence can be switched on or whose fluorescent state can be…”
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Conformationally Locked Chromophores as Models of Excited-State Proton Transfer in Fluorescent Proteins by Baranov, Mikhail S., Lukyanov, Konstantin A., Borissova, Alexandra O., Shamir, Jordan, Kosenkov, Dmytro, Slipchenko, Lyudmila V., Tolbert, Laren M., Yampolsky, Ilia V., Solntsev, Kyril M.

“…Members of the green fluorescent protein (GFP) family form chromophores by modifications of three internal amino acid residues. Previously, many key…”
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Genetically Encoded Fluorescent Sensors for SARS-CoV-2 Papain-like Protease PLpro by Sokolinskaya, Elena L., Putlyaeva, Lidia V., Polinovskaya, Vasilisa S., Lukyanov, Konstantin A.

“…In the SARS-CoV-2 lifecycle, papain-like protease PLpro cuts off the non-structural proteins nsp1, nsp2, and nsp3 from a large polyprotein. This is the…”
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Relationship between intracellular pH, metabolic co-factors and caspase-3 activation in cancer cells during apoptosis by Sergeeva, Tatiana F., Shirmanova, Marina V., Zlobovskaya, Olga A., Gavrina, Alena I., Dudenkova, Varvara V., Lukina, Maria M., Lukyanov, Konstantin A., Zagaynova, Elena V.

“…A complex cascade of molecular events occurs in apoptotic cells but cell-to-cell variability significantly complicates determination of the order and…”
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KillerOrange, a Genetically Encoded Photosensitizer Activated by Blue and Green Light by Sarkisyan, Karen S, Zlobovskaya, Olga A, Gorbachev, Dmitry A, Bozhanova, Nina G, Sharonov, George V, Staroverov, Dmitriy B, Egorov, Evgeny S, Ryabova, Anastasia V, Solntsev, Kyril M, Mishin, Alexander S, Lukyanov, Konstantin A

“…Genetically encoded photosensitizers, proteins that produce reactive oxygen species when illuminated with visible light, are increasingly used as optogenetic…”
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Transient Fluorescence Labeling: Low Affinity-High Benefits by Perfilov, Maxim M, Gavrikov, Alexey S, Lukyanov, Konstantin A, Mishin, Alexander S

“…Fluorescent labeling is an established method for visualizing cellular structures and dynamics. The fundamental diffraction limit in image resolution was…”
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Bright far-red fluorescent protein for whole-body imaging by Chudakov, Dmitriy M, Shcherbo, Dmitry, Merzlyak, Ekaterina M, Chepurnykh, Tatiana V, Fradkov, Arkady F, Ermakova, Galina V, Solovieva, Elena A, Lukyanov, Konstantin A, Bogdanova, Ekaterina A, Zaraisky, Andrey G, Lukyanov, Sergey

“…For deep imaging of animal tissues, the optical window favorable for light penetration is in near-infrared wavelengths, which requires proteins with emission…”
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Red-Shifted Fluorescent Aminated Derivatives of a Conformationally Locked GFP Chromophore by Baranov, Mikhail S., Solntsev, Kyril M., Baleeva, Nadezhda S., Mishin, Alexander S., Lukyanov, Sergey A., Lukyanov, Konstantin A., Yampolsky, Ilia V.

“…A novel class of fluorescent dyes based on conformationally locked GFP chromophore is reported. These dyes are characterized by red‐shifted spectra, high…”
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Natural-Target-Mimicking Translocation-Based Fluorescent Sensor for Detection of SARS-CoV-2 PLpro Protease Activity and Virus Infection in Living Cells by Sokolinskaya, Elena L, Ivanova, Olga N, Fedyakina, Irina T, Ivanov, Alexander V, Lukyanov, Konstantin A

“…Papain-like protease PLpro, a domain within a large polyfunctional protein, nsp3, plays key roles in the life cycle of SARS-CoV-2, being responsible for the…”
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Genetically Encoded Red Photosensitizers with Enhanced Phototoxicity by Gorbachev, Dmitry A, Staroverov, Dmitry B, Lukyanov, Konstantin A, Sarkisyan, Karen S

“…Genetically encoded photosensitizers are increasingly used as optogenetic tools to control cell fate or trigger intracellular processes. A monomeric red…”
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Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival by Gurskaya, Nadya G, Lukyanov, Konstantin A, Hengst, Ulrich, Jaffrey, Samie R, Cox, Llewellyn J

“…During development of the nervous system, axons and growth cones contain mRNAs such as β -actin, cofilin and RhoA , which are locally translated in response to…”
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Studying Chromatin Epigenetics with Fluorescence Microscopy by Stepanov, Afanasii I., Besedovskaia, Zlata V., Moshareva, Maria A., Lukyanov, Konstantin A., Putlyaeva, Lidia V.

“…Epigenetic modifications of histones (methylation, acetylation, phosphorylation, etc.) are of great importance in determining the functional state of…”
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Engineering of a monomeric green-to-red photoactivatable fluorescent protein induced by blue light by Lukyanov, Konstantin A, Gurskaya, Nadya G, Verkhusha, Vladislav V, Shcheglov, Alexander S, Staroverov, Dmitry B, Chepurnykh, Tatyana V, Fradkov, Arkady F, Lukyanov, Sergey

“…Green fluorescent protein (GFP) and GFP-like proteins represent invaluable genetically encoded fluorescent probes. In the last few years a new class of…”
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A Single Fluorescent Protein-Based Indicator with a Time-Resolved Fluorescence Readout for Precise pH Measurements in the Alkaline Range by Simonyan, Tatiana R., Protasova, Elena A., Mamontova, Anastasia V., Shakhov, Aleksander M., Lukyanov, Konstantin A., Maksimov, Eugene G., Bogdanov, Alexey M.

“…The real-time monitoring of the intracellular pH in live cells with high precision represents an important methodological challenge. Although genetically…”
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Computational redesign of a fluorogen activating protein with Rosetta by Bozhanova, Nina G, Harp, Joel M, Bender, Brian J, Gavrikov, Alexey S, Gorbachev, Dmitry A, Baranov, Mikhail S, Mercado, Christina B, Zhang, Xuan, Lukyanov, Konstantin A, Mishin, Alexander S, Meiler, Jens

“…The use of unnatural fluorogenic molecules widely expands the pallet of available genetically encoded fluorescent imaging tools through the design of fluorogen…”
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Insight into redox regulation of apoptosis in cancer cells with multiparametric live-cell microscopy by Shirmanova, Marina V., Gavrina, Alena I., Kovaleva, Tatiana F., Dudenkova, Varvara V., Zelenova, Ekaterina E., Shcheslavskiy, Vladislav I., Mozherov, Artem M., Snopova, Ludmila B., Lukyanov, Konstantin A., Zagaynova, Elena V.

“…Cellular redox status and the level of reactive oxygen species (ROS) are important regulators of apoptotic potential, playing a crucial role in the growth of…”
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Genetically encoded far-red fluorescent sensors for caspase-3 activity by Zlobovskaya, Olga A, Sergeeva, Tatiana F, Shirmanova, Marina V, Dudenkova, Varvara V, Sharonov, George V, Zagaynova, Elena V, Lukyanov, Konstantin A

“…Caspase-3 is a key effector caspase that is activated in both extrinsic and intrinsic pathways of apoptosis. Available fluorescent sensors for caspase-3…”
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