Search Results - "LUKAS, T"

Flat monodromies and a Moduli Space Size Conjecture by Hebecker, Arthur, Henkenjohann, Philipp, Witkowski, Lukas T.

“…A bstract We investigate how super-Planckian axions can arise when type IIB 3-form flux is used to restrict a two-axion field space to a one-dimensional…”
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Can gravitational instantons really constrain axion inflation? by Hebecker, Arthur, Mangat, Patrick, Theisen, Stefan, Witkowski, Lukas T.

“…A bstract Axions play a central role in inflationary model building and other cosmological applications. This is mainly due to their flat potential, which is…”
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Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10 by Saxton, Robert A, Tsutsumi, Naotaka, Su, Leon L, Abhiraman, Gita C, Mohan, Kritika, Henneberg, Lukas T, Aduri, Nanda G, Gati, Cornelius, Garcia, K Christopher

“…Interleukin-10 (IL-10) is an immunoregulatory cytokine with both anti-inflammatory and immunostimulatory properties and is frequently dysregulated in disease…”
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D7-brane chaotic inflation by Hebecker, Arthur, Kraus, Sebastian C., Witkowski, Lukas T.

“…We analyze string-theoretic large-field inflation in the regime of spontaneously-broken supergravity with conventional moduli stabilization by fluxes and…”
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Decoding the messaging of the ubiquitin system using chemical and protein probes by Henneberg, Lukas T, Schulman, Brenda A

“…Post-translational modification of proteins by ubiquitin is required for nearly all aspects of eukaryotic cell function. The numerous targets of…”
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Winding out of the Swamp: Evading the weak gravity conjecture with F-term winding inflation? by Hebecker, Arthur, Mangat, Patrick, Rompineve, Fabrizio, Witkowski, Lukas T.

“…We present a new model of large field inflation along a winding trajectory in the field space of two axionic fields, where the “axions” originate from the…”
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Primordial gravitational waves from excited states by Fumagalli, Jacopo, Palma, Gonzalo A., Renaux-Petel, Sébastien, Sypsas, Spyros, Witkowski, Lukas T., Zenteno, Cristobal

“…A bstract We show that a scalar excited state with large occupation numbers during inflation leads to an enhancement of tensor modes and a characteristic…”
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How REM sleep shapes hypothalamic computations for feeding behavior by Oesch, Lukas T., Adamantidis, Antoine R.

“…The electrical activity of diverse brain cells is modulated across states of vigilance, namely wakefulness, non-rapid eye movement (NREM) sleep, and rapid eye…”
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Revisiting Coleman-de Luccia transitions in the AdS regime using holography by Ghosh, Jewel K., Kiritsis, Elias, Nitti, Francesco, Witkowski, Lukas T.

“…A bstract Coleman-de Luccia processes for AdS to AdS decays in Einstein-scalar theories are studied. Such tunnelling processes are interpreted as vev-driven…”
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Turning in the landscape: A new mechanism for generating primordial black holes by Fumagalli, Jacopo, Renaux-Petel, Sébastien, Ronayne, John W., Witkowski, Lukas T.

“…We propose a new model-independent mechanism for producing primordial black holes from a period of multi-field inflation. This requires an enhancement of…”
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What is the magnetic Weak Gravity Conjecture for axions? by Hebecker, Arthur, Henkenjohann, Philipp, Witkowski, Lukas T.

“…The electric Weak Gravity Conjecture demands that axions with large decay constant f couple to light instantons. The resulting large instantonic corrections…”
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MicroRNA regulation of T-cell differentiation and function by Jeker, Lukas T., Bluestone, Jeffrey A.

“…Summary MicroRNAs (miRNAs) are emerging as key controllers of T‐cell differentiation and function. Their expression is dynamically regulated by extracellular…”
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T helper cells exhibit a dynamic and reversible 3'-UTR landscape by Seyres, Denis, Gorka, Oliver, Schmidt, Ralf, Marone, Romina, Zavolan, Mihaela, Jeker, Lukas T

“…3' untranslated regions (3' UTRs) are critical elements of messenger RNAs, as they contain binding sites for RNA-binding proteins (RBPs) and microRNAs that…”
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From innate to instructed: A new look at perceptual decision-making by Oesch, Lukas T., Ryan, Michael B., Churchland, Anne K.

“…Understanding how subjects perceive sensory stimuli in their environment and use this information to guide appropriate actions is a major challenge in…”
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Systemwide disassembly and assembly of SCF ubiquitin ligase complexes by Baek, Kheewoong, Scott, Daniel C., Henneberg, Lukas T., King, Moeko T., Mann, Matthias, Schulman, Brenda A.

“…Cells respond to environmental cues by remodeling their inventories of multiprotein complexes. Cellular repertoires of SCF (SKP1-CUL1-F box protein) ubiquitin…”
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Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo by Bluestone, Jeffrey A, Zhou, Xuyu, Bailey-Bucktrout, Samantha L, Jeker, Lukas T, Penaranda, Cristina, Martínez-Llordella, Marc, Ashby, Meredith, Nakayama, Maki, Rosenthal, Wendy

“…The stability of expression of the transcription factor Foxp3 in vivo has not been thoroughly assessed. Bluestone and colleagues find that Foxp3 expression can…”
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Tuning and backreaction in F-term axion monodromy inflation by Hebecker, Arthur, Mangat, Patrick, Rompineve, Fabrizio, Witkowski, Lukas T.

“…We continue the development of axion monodromy inflation, focusing in particular on the backreaction of complex structure moduli. In our setting, the shift…”
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MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production by Pua, Heather H., Steiner, David F., Patel, Sana, Gonzalez, Jeanmarie R., Ortiz-Carpena, Jorge F., Kageyama, Robin, Chiou, Ni-Ting, Gallman, Antonia, de Kouchkovsky, Dimitri, Jeker, Lukas T., McManus, Michael T., Erle, David J., Ansel, K. Mark

“…MicroRNAs (miRNAs) are important regulators of cell fate decisions in immune responses. They act by coordinate repression of multiple target genes, a property…”
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Highly Efficient and Versatile Plasmid-Based Gene Editing in Primary T Cells by Kornete, Mara, Marone, Romina, Jeker, Lukas T

“…Adoptive cell transfer is an important approach for basic research and emerges as an effective treatment for various diseases, including infections and blood…”
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Leveraging microRNAs for cellular therapy by Hasiuk, Marko, Dölz, Marianne, Marone, Romina, Jeker, Lukas T.

“…•Cellular therapy, in particular T cell therapy, has demonstrated remarkable clinical success.•Cellular therapies are rapidly becoming programmable…”
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