Search Results - "LUKAS, M. A"

Differentiation of matrix functionals using triangular factorization by DE HOOG, F. R., ANDERSSEN, R. S., LUKAS, M. A.

“…In various applications, it is necessary to differentiate a matrix functional w({\bf A}({\bf x})) {\bf A}({\bf x}). Usually, the functional itself can be…”
Get full text

Differential effect of β-blocker therapy on insulin resistance as a function of insulin sensitizer use: results from GEMINI by Fonseca, V., Bakris, G. L., Bell, D. S. H., McGill, J. B., Raskin, P., Messerli, F. H., Phillips, R. A., Katholi, R. E., Wright Jr, J. T., Waterhouse, B., Lukas, M. A., Anderson, K. M.

“…Aims  To determine whether the beneficial effects of carvedilol on insulin resistance (IR) are affected by the concomitant use of insulin sensitizers…”
Get full text

Influence of heart rate, blood pressure, and beta-blocker dose on outcome and the differences in outcome between carvedilol and metoprolol tartrate in patients with chronic heart failure: results from the COMET trial by Metra, Marco, Torp-Pedersen, Christian, Swedberg, Karl, Cleland, John G.F., Di Lenarda, Andrea, Komajda, Michel, Remme, Willem J., Lutiger, Beatrix, Scherhag, Armin, Lukas, Mary Ann, Charlesworth, Andrew, Poole-Wilson, Philip A.

“…Aims We studied the influence of heart rate (HR), systolic blood pressure (SBP), and beta-blocker dose on outcome in the 2599 out of 3029 patients in…”
Get full text

Race and the Response to Adrenergic Blockade with Carvedilol in Patients with Chronic Heart Failure by Yancy, Clyde W, Fowler, Michael B, Colucci, Wilson S, Gilbert, Edward M, Bristow, Michael R, Cohn, Jay N, Lukas, Mary Ann, Young, Sarah T, Packer, Milton

“…Heart failure is a substantial public health problem among black Americans. It is more common in the black population than in other populations in the United…”
Get full text

Carvedilol inhibits clinical progression in patients with mild symptoms of heart failure by COLUCCI, W. S, PACKER, M, SACKNER-BERNSTEIN, J. D, YOUNG, S. T, HOLCSLAW, T. L, LUKAS, M. A, BRISTOW, M. R, GILBERT, E. M, COHN, J. N, FOWLER, M. B, KRUEGER, S. K, HERSHBERGER, R, URETSKY, B. F, BOWERS, J. A

“…Background We tested the hypothesis that carvedilol inhibits clinical progression in patients with mildly symptomatic heart failure due to left ventricular…”
Get full text

β-Blocker use and diabetes symptom score: results from the GEMINI study by McGill, J.B, Bakris, G.L, Fonseca, V, Raskin, P, Messerli, F.H, Phillips, R.A, Katholi, R.E, Wright, J.T. Jr, Iyengar, M, Anderson, K.M, Lukas, M.A, Dalal, M.R, Bell, D.S.H

“…The Glycemic Effect in Diabetes Mellitus: Carvedilol-Metoprolol Comparison in Hypertensives (GEMINI) trial compared the metabolic effects of two β-blockers in…”
Get full text

Double-blind, placebo-controlled study of the effects of carvedilol in patients with moderate to severe heart failure : The PRECISE trial by PACKER, M, COLUCCI, W. S, GOTTLIEB, S. S, PEARLE, D, CODY, R. J, GREGORY, J. J, KANTROWITZ, N. E, LEJEMTEL, T. H, YOUNG, S. T, LUKAS, M. A, SHUSTERMAN, N. H, SACKNER-BERNSTEIN, J. D, LIANG, C.-S, GOLDSCHER, D. A, FREEMAN, I, KUKIN, M. L, KINHAL, V, UDELSON, J. E, KLAPHOLZ, M

“…Background Carvedilol has improved the symptomatic status of patients with moderate to severe heart failure in single-center studies, but its clinical effects…”
Get full text

Preclinical and clinical pharmacology of carvedilol by Ruffolo, Jr, R R, Boyle, D A, Venuti, R P, Lukas, M A

“…Carvedilol is a novel multiple-action cardiovascular drug that has recently been introduced to the market for the treatment of mild to moderate hypertension…”
Get more information

The Influence of Budgets on Consumer Spending by Lukas, Marcel F, Howard, Ray Charles “Chuck”

“…Abstract Foundational research in marketing and behavioral economics has revealed a great deal about the psychology of budgeting. However, little is known…”
Get full text

New Mouse Models for Microvillus Inclusion Disease (MVID): Where Do the Inclusions Come From and Are They Cause or Consequence? by Huber, Lukas A., MD

Get full text

The interaction of acyl-CoA with acyl-CoA binding protein and carnitine palmitoyltransferase I by Abo-Hashema, Khaled A.H., Cake, Max H., Lukas, Mark A., Knudsen, Jens

“…The affinity of recombinant rat acyl-CoA binding protein (ACBP) towards acyl-CoAs was investigated using both fluorimetric analysis and isothermal titration…”
Get full text

Development of a multiaction beta blocker. Scientific challenges and regulatory needs by Lessem, J N, Lukas, M A

“…The search for the ideal antihypertensive drug is ongoing. Since hypertension initially is a relatively symptom-free disease, it is important that any agent…”
Get more information

Effect of concomitant digoxin and carvedilol therapy on mortality and morbidity in patients with chronic heart failure by Eichhorn, Eric J, Lukas, Mary Ann, Wu, Boll, Shusterman, Neil

“…We retrospectively performed stepwise logistic regression analysis on 1,509 patients with chronic heart failure in 4 multicenter United States studies and 1…”
Get full text

Asymptotic optimality of generalized cross-validation for choosing the regularization parameter by LUKAS, M. A

Get full text

Effects of metoprolol and carvedilol on pre-existing and new onset diabetes in patients with chronic heart failure: data from the Carvedilol Or Metoprolol European Trial (COMET) by Torp-Pedersen, Christian, Metra, Marco, Charlesworth, Andrew, Spark, Phillip, Lukas, Mary Ann, Poole-Wilson, Philip A, Swedberg, Karl, Cleland, John G F, Di Lenarda, Andrea, Remme, Willem J, Scherhag, Armin

“…Background: β Blocker treatment may worsen glucose metabolism. Objective: To study the development of new onset diabetes in a large cohort of patients with…”
Get full text

Effectiveness of three different doses of carvedilol for exertional angina by Weiss, Robert, Ferry, David, Pickering, Edward, Smith, L.Kent, Dennish, George, Krug-Gourley, Sue, Lukas, MaryAnn

“…Carvedilol is a nonselective β-receptor antagonist with vasodilating properties primarily due to selective α-1 antagonism. This 4-treatment, 5-period,…”
Get full text

Evaluation of the Affinity and Turnover Number of Both Hepatic Mitochondrial and Microsomal Carnitine Acyltransferases:  Relevance to Intracellular Partitioning of Acyl-CoAs by Abo-Hashema, Khaled A. H, Cake, Max H, Lukas, Mark A, Knudsen, Jens

“…Mitochondrial carnitine palmitoyltransferase I (CPT I) and microsomal carnitine acyltransferase I (CAT I) regulate the entry of fatty acyl moieties into their…”
Get full text

The 50 Highest Cited Papers in Hip and Knee Arthroplasty by Holzer, Lukas A., MD, Holzer, Gerold, MD

“…Abstract The 50 highest cited articles related to hip and knee arthroplasty were searched in Thomson ISI Web of Science®. The 50 highest cited articles had up…”
Get full text

Carvedilol protects better against vascular events than metoprolol in heart failure : Results from COMET by REMME, Willem J, TORP-PEDERSEN, Christian, MOULLET, Christine, LUKAS, Mary Ann, CLELAND, John G. F, POOLE-WILSON, Philip A, METRA, Marco, KOMAJDA, Michel, SWEDBERG, Karl, DI LENARDA, Andrea, SPARK, Phillip, SCHERHAG, Armin

“…We explored whether vascular protection by carvedilol could contribute to its superior effects in the treatment of heart failure (HF) compared with metoprolol…”
Get full text

Metabolic Effects of Carvedilol vs Metoprolol in Patients With Type 2 Diabetes Mellitus and Hypertension: A Randomized Controlled Trial by Bakris, George L, Fonseca, Vivian, Katholi, Richard E, McGill, Janet B, Messerli, Franz H, Phillips, Robert A, Raskin, Philip, Wright, Jackson T, Oakes, Rosemary, Lukas, Mary Ann, Anderson, Karen M, Bell, David S. H, GEMINI Investigators, for the

“…CONTEXT β-Blockers have been shown to decrease cardiovascular risk in patients with hypertension and type 2 diabetes mellitus (DM); however, some components of…”
Get full text