Search Results - "LUGTHART, Gertjan"

Human Lymphoid Tissues Harbor a Distinct CD69+CXCR6+ NK Cell Population by Lugthart, Gertjan, Melsen, Janine E, Vervat, Carly, van Ostaijen-Ten Dam, Monique M, Corver, Willem E, Roelen, Dave L, van Bergen, Jeroen, van Tol, Maarten J D, Lankester, Arjan C, Schilham, Marco W

“…Knowledge of human NK cells is based primarily on conventional CD56(bright) and CD56(dim) NK cells from blood. However, most cellular immune interactions occur…”
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Comment to: Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia by Melsen, Janine E., Lugthart, Gertjan, van Ostaijen-ten Dam, Monique M., Schilham, Marco W.

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Human Bone Marrow-Resident Natural Killer Cells Have a Unique Transcriptional Profile and Resemble Resident Memory CD8 + T Cells by Melsen, Janine E, Lugthart, Gertjan, Vervat, Carly, Kielbasa, Szymon M, van der Zeeuw, Sander A J, Buermans, Henk P J, van Ostaijen-Ten Dam, Monique M, Lankester, Arjan C, Schilham, Marco W

“…Human lymphoid tissues harbor, in addition to CD56 and CD56 natural killer (NK) cells, a third NK cell population: CD69 CXCR6 lymphoid tissue (lt)NK cells. The…”
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Single-cell transcriptomics in bone marrow delineates CD56dimGranzymeK+ subset as intermediate stage in NK cell differentiation by Melsen, Janine E., van Ostaijen-ten Dam, Monique M., Schoorl, Dorenda J. A., Schol, Pieter J., van den Homberg, Daphne A. L., Lankester, Arjan C., Lugthart, Gertjan, Schilham, Marco W.

“…Human natural killer (NK) cells in lymphoid tissues can be categorized into three subsets: CD56 bright CD16 + , CD56 dim CD16 + and CD69 + CXCR6 + lymphoid…”
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Protocol for Isolation, Stimulation and Functional Profiling of Primary and iPSC-derived Human NK Cells by Melsen, Janine E, Themeli, Maria, van Ostaijen-Ten Dam, Monique M, van Beelen, Els, Lugthart, Gertjan, Hoeben, Rob C, Schilham, Marco W, Mikkers, Harald M

“…Natural killer (NK) cells are innate immune cells, characterized by their cytotoxic capacity, and chemokine and cytokine secretion upon activation. Human NK…”
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Human Circulating and Tissue-Resident CD56(bright) Natural Killer Cell Populations by Melsen, Janine E, Lugthart, Gertjan, Lankester, Arjan C, Schilham, Marco W

“…Two human natural killer (NK) cell subsets are usually distinguished, displaying the CD56(dim)CD16(+) and the CD56(bright)CD16(-/+) phenotype. This distinction…”
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MO452CHRONIC KIDNEY DISEASE TEN YEARS AFTER PEDIATRIC ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION by Bresters, Dorine, Jol-van der Zijde, Els, Dorresteijn, Eiske, Louwerens, Marloes, Jordans, Carlijn, Lankester, Arjan, Lugthart, Gertjan, De Pagter, Anne, Van Rooij-Kouwenhoven, Roos, Sukhai, Ram

“…Abstract Background and Aims Chronic kidney disease (CKD) is an important sequela of hematopoietic stem cell transplantation (HSCT), but data regarding CKD…”
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Severe Pediatric COVID-19 and Multisystem Inflammatory Syndrome in Children From Wild-type to Population Immunity: A Prospective Multicenter Cohort Study With Real-time Reporting by Tulling, Adam J., Lugthart, Gertjan, Mooij, Miriam G., Brackel, Caroline L. H., Terheggen-Lagro, Suzanne W. J., Oostenbrink, Rianne, Buysse, Corinne M. P., Hashimoto, Simone, Armbrust, Wineke, Bannier, Michiel A. G. E., Bekhof, Jolita, van Gameren-Oosterom, Helma B., Hendriks, Han, van Houten, Marlies A., van der Linden, Jan W., Lebon, Ankie, van Onzenoort-Bokken, Lonneke, Tramper-Stranders, Gerdien A., van Veen, Mirjam, von Asmuth, Erik G. J., Buddingh, Emilie P.

“…Background: SARS-CoV-2 variant evolution and increasing immunity altered the impact of pediatric SARS-CoV-2 infection. Public health decision-making relies on…”
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Post-COVID-19 condition in children: epidemiological evidence stratified by acute disease severity by Lap, Coen R, Brackel, Caroline L H, Winkel, Angelique M A M, Hashimoto, Simone, Haverkort, Milly, Noij, Lieke C E, Alsem, Mattijs W, von Asmuth, Erik G J, Bannier, Michiel A G E, Buddingh, Emmeline P, van Goudoever, Johannes B, Haverman, Lotte, van der Zee, Anke H Maitland, Mooij, Miriam G, Oostrom, Kim, Pijnenburg, Mariëlle W, Kloosterman, Sanne, Teela, Lorynn, Luijten, Michiel, Tulling, Adam J, Lugthart, Gertjan, Bogaert, Debby, Biesbroek, Giske, van Houten, Marlies A, Terheggen-Lagro, Suzanne W J

“…To determine the prevalence of pediatric Post-COVID-19 condition (PPCC), identify risk factors, and assess the quality of life in children with differing…”
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Serum proteomics reveals hemophagocytic lymphohistiocytosis-like phenotype in a subset of patients with multisystem inflammatory syndrome in children by Tulling, Adam J., Holierhoek, Marloes G., Jansen-Hoogendijk, Anja M., Hoste, Levi, Haerynck, Filomeen, Tavernier, Simon J., Oostenbrink, Rianne, Buysse, Corinne M.P., Bannier, Michiel A.G.E., Bekhof, Jolita, Breukels, Mijke, Hammer, Sanne C., Jacobs, Monique A.M., Kamps, Arvid W.A., van der Linden, Jan W., Lebon, Ankie, Oudshoorn, Johanna H., Tramper-Stranders, Gerdien A., Vastert, Sebastiaan J., Wieringa, Jantien W., Terheggen-Lagro, Suzanne W.J., Wildenbeest, Joanne G., von Asmuth, Erik G.J., van den Akker, Erik B., van Gijn, Marielle E., Lugthart, Gertjan, Buddingh, Emilie P.

“…Children with Multisystem Inflammatory Syndrome in Children (MIS-C) can present with thrombocytopenia, which is a key feature of hemophagocytic…”
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CD56(dim)CD16⁻ NK cell phenotype can be induced by cryopreservation by Lugthart, Gertjan, van Ostaijen-ten Dam, Monique M, van Tol, Maarten J D, Lankester, Arjan C, Schilham, Marco W

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Expansion of cytotoxic CD56brightnatural killer cells during T-cell deficiency after allogeneic hematopoietic stem cell transplantation by Lugthart, Gertjan, Goedhart, Marieke, van Leeuwen, Merle M, Melsen, Janine E, Cornelia M Jol-van der Zijde, Vervat, Carly, Monique M van Ostaijen-ten Dam, Jansen-Hoogendijk, Anja M, Maarten JD van Tol, Lankester, Arjan C, Schilham, Marco W

“…The role of NK cells in immunity may normally be overshadowed by the presence of T cells.[...]transient T-cell deficiency after HSCT provides an opportunity to…”
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CD69 and CXCR6 Identify a Distinct Population of Human Bone Marrow and Spleen Resident NK Cells by Lugthart, Gertjan, Vervat, Carly, Melsen, Janine E, Van Ostaijen-ten Dam, Monique M, Roelen, Dave L, van Tol, Maarten JD, Lankester, Arjan C, Schilham, Marco W

“…In recent years, evidence has been provided that natural killer (NK) cells can function as anti-leukemic effector cells. In humans, two NK cell populations are…”
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Human Circulating and Tissue-Resident CD56bright Natural Killer Cell Populations by Melsen, Janine E., Lugthart, Gertjan, Lankester, Arjan C., Schilham, Marco W.

“…Two human natural killer (NK) cell subsets are usually distinguished, displaying the CD56 dim CD16 + and the CD56 bright CD16 −/+ phenotype. This distinction…”
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CD56dimCD16− NK cell phenotype can be induced by cryopreservation by Lugthart, Gertjan, van Ostaijen-ten Dam, Monique M., van Tol, MaartenJ.D., Lankester, Arjan C., Schilham, Marco W.

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Expansion of cytotoxic CD56 bright natural killer cells during T-cell deficiency after allogeneic hematopoietic stem cell transplantation by Lugthart, Gertjan, Goedhart, Marieke, van Leeuwen, Merle M, Melsen, Janine E, Jol-van der Zijde, Cornelia M, Vervat, Carly, van Ostaijen-Ten Dam, Monique M, Jansen-Hoogendijk, Anja M, van Tol, Maarten J D, Lankester, Arjan C, Schilham, Marco W

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Expansion of cytotoxic CD56bright natural killer cells during T-cell deficiency after allogeneic hematopoietic stem cell transplantation by Lugthart, Gertjan, Goedhart, Marieke, van Leeuwen, Merle M., Melsen, Janine E., Jol-van der Zijde, Cornelia M., Vervat, Carly, van Ostaijen-ten Dam, Monique M., Jansen-Hoogendijk, Anja M., van Tol, Maarten J.D., Lankester, Arjan C., Schilham, Marco W.

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Single-cell transcriptomics in bone marrow delineates CD56 dim GranzymeK + subset as intermediate stage in NK cell differentiation by Melsen, Janine E, van Ostaijen-Ten Dam, Monique M, Schoorl, Dorenda J A, Schol, Pieter J, van den Homberg, Daphne A L, Lankester, Arjan C, Lugthart, Gertjan, Schilham, Marco W

“…Human natural killer (NK) cells in lymphoid tissues can be categorized into three subsets: CD56 CD16 , CD56 CD16 and CD69 CXCR6 lymphoid tissue-resident (lt)NK…”
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Imprint Of Early CMV Reactivation On The Reconstituting T-Lymphocyte Compartment One and Two Year After Hematopoietic Stem Cell Transplantation by Lugthart, Gertjan, van Ostaijen-Ten Dam, Monique M., Jol-van der Zijde, Cornelia M., van Holten, Tessa C., Kester, Michel G.D., Heemskerk, Mirjam H.M., Bredius, Robbert G.M., van Tol, Maarten J.D., Lankester, Arjan C.

“…Cytomegalovirus (CMV) reactivation frequently occurs during early immune reconstitution after hematopoietic stem cell transplantation (HSCT). Although CMV is…”
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The Effectiveness Of Cidofovir In Disseminated Adenovirus Infections After Pediatric HSCT Is Closely Related To Lymphocyte Reconstitution by Lugthart, Gertjan, Oomen, Marloes A., Jol-van der Zijde, Cornelia M., Ball, Lynne M., Bresters, Dorine, Kollen, Wouter J.W., Smiers, Frans J., Vermont, Clementien L., Bredius, Robbert G.M., Schilham, Marco W., van Tol, Maarten J.D., Lankester, Arjan C.

“…Human Adenovirus (HAdV) reactivation is a frequent and potentially fatal complication in pediatric allogeneic stem cell transplantation (HSCT) recipients,…”
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