Search Results - "LUDLAM, C. A."

Guidelines for the management of hemophilia by Srivastava, A., Brewer, A. K., Mauser-Bunschoten, E. P., Key, N. S., Kitchen, S., Llinas, A., Ludlam, C. A., Mahlangu, J. N., Mulder, K., Poon, M. C., Street, A.

“…Summary Hemophilia is a rare disorder that is complex to diagnose and to manage. These evidence‐based guidelines offer practical recommendations on the…”
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Detection of a novel DNA virus (TT virus) in blood donors and blood products by Simmonds, P, Davidson, F, Lycett, C, Prescott, LE, MacDonald, DM, Ellender, J, Yap, PL, Haydon, GH, Gillon, J, Jarvis, LM, Ludlam, CA

“…A newly discovered DNA virus, transfusion- transmitted virus (TTV), has been implicated as a cause of post-transfusion hepatitis. We investigated the frequency…”
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The treatment of bleeding in acquired haemophilia with recombinant factor VIIa: a multicentre study by Hay, C R, Negrier, C, Ludlam, C A

“…Recombinant factor VIIa was used to treat 38 patients with acquired haemophilia participating in the Novoseven compassionate-use program. 19 were male, median…”
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The procoagulant potential of environmental particles (PM10) by Gilmour, P S, Morrison, E R, Vickers, M A, Ford, I, Ludlam, C A, Greaves, M, Donaldson, K, MacNee, W

“…Background and Aims: Epidemiology studies have shown that cardiovascular (CV) disease is primarily responsible for the mortality associated with increased…”
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Infection with hepatitis G virus among recipients of plasma products by Jarvis, L M, Davidson, F, Hanley, J P, Yap, P L, Ludlam, C A, Simmonds, P

“…Hepatitis G virus (HGV or GBV-C) is a newly discovered human flavivirus distantly related to hepatitis C virus (HCV). Little information is available on its…”
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Effects of acute liver injury on blood coagulation by Kerr, R., Newsome, P., Germain, L., Thomson, E., Dawson, P., Stirling, D., Ludlam, C. A.

“…The mechanisms leading to the hemostatic changes of acute liver injury are poorly understood. To study these further we have assessed coagulation and immune…”
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Endothelial dysfunction, impaired endogenous fibrinolysis, and cigarette smoking : A mechanism for arterial thrombosis and myocardial infarction by NEWBY, D. E, WRIGHT, R. A, LABINJOH, C, LUDLAM, C. A, FOX, K. A. A, BOON, N. A, WEBB, D. J

“…Effective endogenous fibrinolysis requires rapid release of tissue plasminogen activator (tPA) from the vascular endothelium. Smoking is a known risk factor…”
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Phosphodiesterase type 5 inhibition does not reverse endothelial dysfunction in patients with coronary heart disease by Robinson, S D, Ludlam, C A, Boon, N A, Newby, D E

“…Objectives: To investigate whether sildenafil citrate, a selective phosphodiesterase type 5 inhibitor, may improve endothelial vasomotor and fibrinolytic…”
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Hepatitis C infection and outcomes in the Scottish haemophilia population by Khan, M. M., Tait, R. C., Kerr, R., Ludlam, C. A., Lowe, G. D. O., Murray, W., Watson, H. G.

“…Summary Patients with bleeding disorders previously frequently became infected with hepatitis C virus. We identified the number of patients infected in…”
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Use of porcine factor VIII in the treatment of patients with acquired hemophilia by MORRISON, A. E, LUDLAM, C. A, KESSLER, C

“…Data have been collected from 47 centers in Europe and North America on the treatment with porcine factor VIII concentrate of 74 acute bleeding episodes in 65…”
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Early increase in levels of soluble inter-cellular adhesion molecule-1 (sICAM-1). Potential risk factor for the acute coronary syndromes by O'malley, T, Ludlam, C.A, Riemermsa, R.A, Fox, K.A.A

“…Background Studies have shown disparate results in relation to the role of plasma concentrations of cell adhesion molecules in atherosclerosis. Moreover, the…”
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Human Parvovirus B19 and Blood Products by Prowse, C., Ludlam, C. A., Yap, P. L.

“…Background and objectives: Human B19 parvovirus (B19), identified in 1975, was only recognised as the causative agent of fifth disease in 1983. The incidence…”
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Human immunodeficiency virus-infected individuals contain provirus in small numbers of peripheral mononuclear cells and at low copy numbers by SIMMONDS, P, BALFE, P, PEUTHERER, J. F, LUDLAM, C. A, BISHOP, J. O, LEIGH BROWN, A. J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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TT Virus—Part of the Normal Human Flora? by Simmonds, P., Prescott, L. E., Logue, C., Davidson, F., Thomas, A. E., Ludlam, C. A.

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Acute endothelial tissue plasminogen activator release in pregnancy by ROBB, A. O., MILLS, N. L., DIN, J. N., CAMERON, S., LUDLAM, C. A., NEWBY, D. E., DENISON, F. C.

“…Objective: Pregnancy is associated with marked changes in vascular physiology and an increased risk of thrombosis. The aim of the study was to assess the…”
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Analysis of sequence diversity in hypervariable regions of the external glycoprotein of human immunodeficiency virus type 1 by SIMMONDS, P, BALFE, P, LUDLAM, C. A, BISHOP, J. O, BROWN, A. J. L

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Coagulation and fibrinolysis in patients undergoing operation for ruptured and nonruptured infrarenal abdominal aortic aneurysms by Adam, Donald J., Ludlam, Christopher A., Ruckley, C.Vaughan, Bradbury, Andrew W.

“…Purpose : Hemorrhage and thrombosis predisposing to myocardial infarction, multiple organ failure, and thromboembolism account for the majority of the…”
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Prevalence of pernicious anaemia in patients with Type 1 diabetes mellitus and autoimmune thyroid disease by Perros, P., Singh, R. K., Ludlam, C. A., Frier, B. M.

“…SUMMARY Aims  To determine the prevalence of pernicious anaemia in patients with Type 1 diabetes mellitus and autoimmune thyroid disease. Methods  A randomly…”
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Convergent and Divergent Sequence Evolution in the Surface Envelope Glycoprotein of Human Immunodeficiency Virus Type 1 within a Single Infected Patient by Holmes, Edward C., Zhang, Lin Qi, Simmonds, Peter, Ludlam, Christopher A., Andrew J. Leigh Brown

“…In an investigation of the evolution of the third hypervariable loop of gp120 (V3), the principal neutralization determinant of human immunodeficiency virus…”
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Effects of acute angiotensin II type 1 receptor antagonism and angiotensin converting enzyme inhibition on plasma fibrinolytic parameters in patients with heart failure by GOODFIELD, N. E. R, NEWBY, D. E, LUDLAM, C. A, FLAPAN, A. D

“…Angiotensin converting enzyme (ACE) inhibition after myocardial infarction is associated with an improvement in plasma fibrinolytic parameters. The aim of the…”
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