Search Results - "LUDĚK BLÁHA"
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What level of estrogenic activity determined by in vitro assays in municipal waste waters can be considered as safe?
Published in Environment international (01-03-2014)“…In vitro assays are broadly used tools to evaluate the estrogenic activity in Waste Water Treatment Plant (WWTP) effluents and their receiving rivers. Since…”
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Assessment of Hepatotoxic Potential of Cyanobacterial Toxins Using 3D In Vitro Model of Adult Human Liver Stem Cells
Published in Environmental science & technology (04-09-2018)“…Cyanotoxins microcystin-LR (MC-LR) and cylindrospermopsin (CYN) represent hazardous waterborne contaminants and potent human hepatotoxins. However, in vitro…”
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Altered Transcriptome Response in PBMCs of Czech Adults Linked to Multiple PFAS Exposure: B Cell Development as a Target of PFAS Immunotoxicity
Published in Environmental science & technology (09-01-2024)“…While the immunomodulation effects of per- and polyfluoroalkyl substances (PFASs) are described on the level of clinical signs in epidemiological studies…”
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Levels and risks of surface contamination by thirteen antineoplastic drugs in the Czech and Slovak hospitals and pharmacies
Published in Environmental science and pollution research international (01-04-2022)“…The consumption of hazardous antineoplastic drugs (ADs) used in anticancer chemotherapies is steadily increasing representing thus risks to both human health…”
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Drinking water contaminants from epoxy resin-coated pipes: A field study
Published in Water research (Oxford) (15-10-2016)“…Rehabilitation of aged drinking water pipes is an extensive renovation and increasingly topical in many European cities. Spray-on-lining of drinking water…”
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Mitochondrial Toxicity of Microcystin-LR on Cultured Cells: Application to the Analysis of Contaminated Water Samples
Published in Environmental science & technology (01-04-2010)“…Microcystins (MC) are potent hepatic toxins delivered into the cells by organic anion transporting peptides (OATP) where they target protein phosphatases and…”
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Complex evaluation of ecotoxicity and genotoxicity of antimicrobials oxytetracycline and flumequine used in aquaculture
Published in Environmental toxicology and chemistry (01-05-2011)“…Ecotoxicity and genotoxicity of widely used veterinary antimicrobials oxytetracycline and flumequine was studied with six model organisms (Vibrio fischeri,…”
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The efficiency of antineoplastic drug contamination removal by widely used disinfectants–laboratory and hospital studies
Published in International archives of occupational and environmental health (01-10-2021)“…Objective Antineoplastic drugs (ADs) pose risks to healthcare staff. Surface disinfectants are used in hospitals to prevent microbial contamination but the…”
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Is environmental risk assessment possible with the alternatives to acute fish toxicity test? Case study with pharmaceuticals
Published in Environmental sciences Europe (05-11-2024)“…Background Acute fish toxicity test (AFT) is one of the cornerstones of environmental risk assessment (ERA) of chemicals for the aquatic environment. Despite…”
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Comparison of imidacloprid, propiconazole, and nanopropiconazole effects on the development, behavior, and gene expression biomarkers of the Pacific oyster (Magallana gigas)
Published in The Science of the total environment (10-04-2021)“…Coastal areas are final recipients of various contaminants including pesticides. The effects of pesticides on non-target organisms are often unclear,…”
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Dioxins and dioxin-like compounds in composts and digestates from European countries as determined by the in vitro bioassay and chemical analysis
Published in Chemosphere (Oxford) (01-03-2015)“…Aerobic composting and anaerobic digestion plays an important role in reduction of organic waste by transforming the waste into humus, which is an excellent…”
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Toxins produced in cyanobacterial water blooms - toxicity and risks
Published in Interdisciplinary toxicology (01-06-2009)“…Cyanobacterial blooms in freshwaters represent a major ecological and human health problem worldwide. This paper briefly summarizes information on major…”
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Phytoestrogens and sterols in waters with cyanobacterial blooms - Analytical methods and estrogenic potencies
Published in Chemosphere (Oxford) (01-03-2017)“…Compounds with estrogenic potencies and their adverse effects in surface waters have received much attention. Both anthropogenic and natural compounds…”
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Evaluation of extraction approaches linked to ELISA and HPLC for analyses of microcystin-LR, -RR and -YR in freshwater sediments with different organic material contents
Published in Analytical and bioanalytical chemistry (01-08-2006)“…The efficiencies of conventional extraction techniques and analytical methods (HPLC-DAD and ELISA) were investigated for analyses of microcystins (MCs) in…”
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Pesticide mixture toxicity assessment through in situ and laboratory approaches using embryo-larval stages of the pacific oyster (Magallana gigas)
Published in Marine environmental research (01-07-2021)“…Worsened state of oysters in French Arcachon Bay, demand an investigation of possible causes. This study evaluated the effects of an environmentally relevant…”
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Levels and risks of antineoplastic drugs in households of oncology patients, hospices and retirement homes
Published in Environmental sciences Europe (01-12-2021)“…Background Contamination of the indoor environment by antineoplastic drugs (ADs) is known to pose health risks to the exposed staff in hospitals or pharmacies…”
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Can zero-valent iron nanoparticles remove waterborne estrogens?
Published in Journal of environmental management (01-03-2015)“…Steroidal estrogens are one of the most challenging classes of hazardous contaminants as they can cause adverse effects to biota in extremely low…”
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Synthetic Biomimetic Polymethacrylates: Promising Platform for the Design of Anti-Cyanobacterial and Anti-Algal Agents
Published in Polymers (26-03-2021)“…Extensive, uncontrolled growth of algae and cyanobacteria is an environmental, public health, economic, and technical issue in managing natural and engineered…”
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The first occurrence of the cyanobacterial alkaloid toxin cylindrospermopsin in the Czech Republic as determined by immunochemical and LC/MS methods
Published in Toxicon (Oxford) (01-04-2009)“…Cylindrospermopsin (CYN) is a newly emerging carcinogenic alkaloid originally identified in tropical cyanobacteria Cylindrospermopsis raciborskii. Some recent…”
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