Search Results - "LUCIE BLÁHOVÁ"
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Triphenyl Phosphate Alters Methyltransferase Expression and Induces Genome-Wide Aberrant DNA Methylation in Zebrafish Larvae
Published in Chemical research in toxicology (16-09-2024)“…Emerging environmental contaminants, organophosphate flame retardants (OPFRs), pose significant threats to ecosystems and human health. Despite numerous…”
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Levels and risks of surface contamination by thirteen antineoplastic drugs in the Czech and Slovak hospitals and pharmacies
Published in Environmental science and pollution research international (01-04-2022)“…The consumption of hazardous antineoplastic drugs (ADs) used in anticancer chemotherapies is steadily increasing representing thus risks to both human health…”
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Environmentally relevant mixture of S-metolachlor and its two metabolites affects thyroid metabolism in zebrafish embryos
Published in Aquatic toxicology (01-04-2020)“…•Reduced embryonal movements caused by S-metolachlor and its mixture with metabolites.•Gene modulations caused by MESA and MOA metabolites; not by parent…”
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The efficiency of antineoplastic drug contamination removal by widely used disinfectants–laboratory and hospital studies
Published in International archives of occupational and environmental health (01-10-2021)“…Objective Antineoplastic drugs (ADs) pose risks to healthcare staff. Surface disinfectants are used in hospitals to prevent microbial contamination but the…”
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Is environmental risk assessment possible with the alternatives to acute fish toxicity test? Case study with pharmaceuticals
Published in Environmental sciences Europe (05-11-2024)“…Background Acute fish toxicity test (AFT) is one of the cornerstones of environmental risk assessment (ERA) of chemicals for the aquatic environment. Despite…”
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Exposure to benzotriazoles and benzothiazoles in Czech male population and its associations with biomarkers of liver function, serum lipids and oxidative stress
Published in International archives of occupational and environmental health (01-07-2024)“…Introduction Benzotriazoles and benzothiazoles (BTs) are high-production volume chemicals as well as widely distributed emerging pollutants with potential…”
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Effects of pesticide exposure on oxidative stress and DNA methylation urinary biomarkers in Czech adults and children from the CELSPAC-SPECIMEn cohort
Published in Environmental research (01-04-2023)“…Current-use pesticide (CUP) exposure occurs mainly through diet and environmental application in both agricultural and urban settings. While pesticide exposure…”
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Comparison of imidacloprid, propiconazole, and nanopropiconazole effects on the development, behavior, and gene expression biomarkers of the Pacific oyster (Magallana gigas)
Published in The Science of the total environment (10-04-2021)“…Coastal areas are final recipients of various contaminants including pesticides. The effects of pesticides on non-target organisms are often unclear,…”
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The Origin of Teratogenic Retinoids in Cyanobacteria
Published in Toxins (01-09-2022)“…Although information about the occurrence and distribution of retinoids in the environment is scarce, cyanobacterial water blooms have been identified as a…”
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Neurobehavioral effects of cyanobacterial biomass field extracts on zebrafish embryos and potential role of retinoids
Published in Aquatic toxicology (01-11-2020)“…•Field cyanobacterial biomass extracts cause behavioural changes in zebrafish.•The effects were localized in fractions with retinoid compounds content.•The…”
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Cyanobacteria, cyanotoxins and lipopolysaccharides in aerosols from inland freshwater bodies and their effects on human bronchial cells
Published in Environmental toxicology and pharmacology (01-03-2023)“…Components of cyanobacterial water blooms were quantified in aerosols above agitated water surfaces of five freshwater bodies. The thoracic and respirable…”
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Proposals of guidance values for surface contamination by antineoplastic drugs based on long term monitoring in Czech and Slovak hospitals and pharmacies
Published in Frontiers in public health (14-09-2023)“…Introduction The exposures to hazardous antineoplastic drugs (AD) represent serious risks for health care personnel but the exposure limits are not commonly…”
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Rapid extraction and analysis of oxidative stress and DNA damage biomarker 8-hydroxy-2′-deoxyguanosine (8-OHdG) in urine: Application to a study with pregnant women
Published in International journal of hygiene and environmental health (01-05-2023)“…Oxidative stress is an important toxicity and genotoxicity mechanism of many chronic adverse health outcomes. This study developed a sensitive extraction…”
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Cyanobacterial lipopeptides puwainaphycins and minutissamides induce disruptive and pro-inflammatory processes in Caco-2 human intestinal barrier model
Published in Harmful algae (01-06-2020)“…•Puwainaphycins and minutissamides are cytotoxic for intestinal epithelial cells.•In nontoxic concentrations they induce production of pro-inflammatory…”
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Pesticide mixture toxicity assessment through in situ and laboratory approaches using embryo-larval stages of the pacific oyster (Magallana gigas)
Published in Marine environmental research (01-07-2021)“…Worsened state of oysters in French Arcachon Bay, demand an investigation of possible causes. This study evaluated the effects of an environmentally relevant…”
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Levels and risks of antineoplastic drugs in households of oncology patients, hospices and retirement homes
Published in Environmental sciences Europe (01-12-2021)“…Background Contamination of the indoor environment by antineoplastic drugs (ADs) is known to pose health risks to the exposed staff in hospitals or pharmacies…”
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The effects of nano-sized PbO on biomarkers of membrane disruption and DNA damage in a sub-chronic inhalation study on mice
Published in Nanotoxicology (07-02-2020)“…Although the production of engineered nanoparticles increases our knowledge of toxicity and mechanisms of bioactivity during relevant exposures is lacking. In…”
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The isolation and characterization of lipopolysaccharides from Microcystis aeruginosa, a prominent toxic water bloom forming cyanobacteria
Published in Toxicon (Oxford) (15-12-2013)“…Massive toxic blooms of cyanobacteria represent a major threat to water supplies worldwide, yet serious gaps exist in understanding their complex toxic…”
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The first occurrence of the cyanobacterial alkaloid toxin cylindrospermopsin in the Czech Republic as determined by immunochemical and LC/MS methods
Published in Toxicon (Oxford) (01-04-2009)“…Cylindrospermopsin (CYN) is a newly emerging carcinogenic alkaloid originally identified in tropical cyanobacteria Cylindrospermopsis raciborskii. Some recent…”
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