Search Results - "LUCATTELLI, M"

Innate Immunity and Cell Surface Receptors in the Pathogenesis of COPD: Insights from Mouse Smoking Models by De Cunto, Giovanna, Cavarra, Eleonora, Bartalesi, Barbara, Lucattelli, Monica, Lungarella, Giuseppe

“…Chronic obstructive pulmonary disease (COPD) is mainly associated with smoking habit. Inflammation is the major initiating process whereby neutrophils and…”
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The dual role of neutrophil elastase in lung destruction and repair by Lungarella, Giuseppe, Cavarra, Eleonora, Lucattelli, Monica, Martorana, Piero A.

“…The purpose of this review was to modify the prevailing view that neutrophil elastase (NE) is mainly a matrix-degrading enzyme. Recent observations indicate…”
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Pulmonary hypertension in smoking mice over-expressing protease-activated receptor-2 by DE CUNTO, G, CARDINI, S, CIRINO, G, GEPPETTI, P, LUNGARELLA, G, LUCATTELLI, M

“…The mechanism(s) involved in the development of pulmonary hypertension (PH) in COPD is still the object of investigation. Cigarette smoke (CS) may lead to…”
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Different lung responses to cigarette smoke in two strains of mice sensitive to oxidants by Bartalesi, B, Cavarra, E, Fineschi, S, Lucattelli, M, Lunghi, B, Martorana, P. A, Lungarella, G

“…The development of cigarette smoke-induced pulmonary changes in C57 Bl/6J and DBA/2 mice was investigated. Both strains are sensitive to oxidants and C57Bl/6J…”
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Expression of substance P, neurokinin 1 receptors (NK1) and neurokinin 3 receptors in the developing mouse retina and in the retina of NK1 knockout mice by Catalani, E., Dal Monte, M., Gangitano, C., Lucattelli, M., Fineschi, S., Bosco, L., Bagnoli, P., Casini, G.

“…To complete a series of studies on the expression of substance P and neurokinin receptors in mammalian retinas, we investigated the occurrence of these…”
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Collagen phagocytosis by lung alveolar macrophages in animal models of emphysema by Lucattelli, M, Cavarra, E, M. de Santi, M, Tetley, T.D, Martorana, P.A, Lungarella, G

“…Under steady state conditions the intracellular pathway is the major route of collagen catabolism in tissues characterised by rapid collagen turnover. In the…”
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GFAP Is Expressed as a Major Soluble Pool Associated with Glucagon Secretory Granules in A-cells of Mouse Pancreas by Bertelli, Eugenio, Regoli, Mari, Gambelli, Federica, Lucattelli, Monica, Lungarella, Giuseppe, Bastianini, Arnaldo

“…To elucidate the role of intermediate filament proteins in endocrine cells, we investigated the expression and subcellular distribution of GFAP in mouse islets…”
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C107 IMMUNITY, EXACERBATION AND IMMUNE CELL FUNCTION IN COPD: Severe Reduction Of Peripheral T Cells Does Not Afford Protection Toward Emphysema And Bronchial Remodelling Induced In Mice By Cigarette Smoke by Lungarella, G, DeCunto, G, Lunghi, B, Bartalesi, B, Cavarra, E, Fineschi, S, Ulivieri, C, Lucattelli, M

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Roflumilast Fully Prevents Emphysema in Mice Chronically Exposed to Cigarette Smoke by Martorana, Piero A, Beume, Rolf, Lucattelli, Monica, Wollin, Lutz, Lungarella, Giuseppe

“…There is a need for new agents capable of suppressing the inflammatory response in chronic obstructive pulmonary disease. This study evaluated the effects of…”
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Effects of cigarette smoke in mice with different levels of alpha(1)-proteinase inhibitor and sensitivity to oxidants by Cavarra, E, Bartalesi, B, Lucattelli, M, Fineschi, S, Lunghi, B, Gambelli, F, Ortiz, L A, Martorana, P A, Lungarella, G

“…The role of strain difference in the response to cigarette smoke was investigated in mice. Mice of the strains DBA/2 and C57BL/6J responded to acute cigarette…”
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Is neutrophil elastase the missing link between emphysema and fibrosis? Evidence from two mouse models by Lucattelli, Monica, Bartalesi, Barbara, Cavarra, Eleonora, Fineschi, Silvia, Lunghi, Benedetta, Martorana, Piero A, Lungarella, Giuseppe

“…The separation of emphysema from fibrosis is not as clear-cut as it was thought in early studies. These two pathologies may be present at the same time in…”
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A new mouse model of Peyronie's disease: An increased expression of hypoxia-inducible factor-1 target genes during the development of penile changes by Lucattelli, Monica, Lunghi, Benedetta, Fineschi, Silvia, Mirone, Vincenzo, di Villa Bianca, Roberta d’Emmanuele, Longo, Nicola, Imbimbo, Ciro, De Palma, Raffaele, Sorrentino, Raffaella, Lungarella, Giuseppe, Cirino, Giuseppe

“…Peyronie's disease (PD) is characterized by an inflammatory response beneath the tunica albuginea with fibroblast proliferation forming a thickened fibrous…”
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Urinary desmosine excretion is inversely correlated with the extent of emphysema in patients with chronic obstructive pulmonary disease by Cocci, Franca, Miniati, Massimo, Monti, Simonetta, Cavarra, Eleonora, Gambelli, Federica, Battolla, Luigi, Lucattelli, Monica, Lungarella, Giuseppe

“…An enhanced proteolysis of lung interstitium is key event in the pathogenesis of emphysema, a major constituent of chronic obstructive pulmonary disease. To…”
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L 17. NK1-R blockade and marine long tumorigenesis. A model for studying the adenoma-carcinoma sequence by Lucattelli, M, Fineschi, S, Geppetti, P, Gerard, N P, Lungarella, G

“…Background and aims. Originally, the aim of the present study was the evaluation of the role of NK-1 receptor (NK-1R) in the lung fibrogenic response to BLM in…”
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Human SLPI inactivation after cigarette smoke exposure in a new in vivo model of pulmonary oxidative stress by Cavarra, E, Lucattelli, M, Gambelli, F, Bartalesi, B, Fineschi, S, Szarka, A, Giannerini, F, Martorana, P A, Lungarella, G

“…The role of oxidative stress in inactivating antiproteases is the object of debate. To address this question, we developed an in vivo model of pulmonary…”
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L 9. Transient receptor potential vanilloid 1, substance P and reactive oxygen species mediate ethanol - induced gastric injury in mice by Geppetti, P, Gazzieri, D, Trevisani, M, Springer, J, Harrison, S, Cottrell, G S, Andre, E, Nicoletti, P, Massi, D, Zecchi, S, Nosi, D, Santucci, M, Gerard, N P, Lucattelli, M

“…Background and aims. Ingestion of elevated amounts of ethanol (EtOH) can cause hemorrhagic ulceration of the stomach in humans and experimental animals by…”
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Reverse Expansion for Breast Reconstruction after Skin-sparing and Nipple-sparing Mastectomy: Our First 100 Cases by Fabiocchi, Luca, Lucattelli, Elena, Cattin, Federico, Cipriani, Federico, Dellachiesa, Laura, Fogacci, Tommaso, Frisoni, Gianluca, Semprini, Gloria, Samorani, Domenico

“…Patients with breast cancer have experienced advancements both in oncological treatment and in aesthetics as a result of developments in reconstructive…”
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Nestin expression in rat adrenal gland by Bertelli, Eugenio, Regoli, Marì, Lucattelli, Monica, Bastianini, Arnaldo, Fonzi, Luciano

“…The constituents of the intermediate filament network of adrenal gland cells have not been deeply investigated in vivo. Adrenocortical cells have been reported…”
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Roflumilast fully prevents emphysema in mice chronically exposed to cigarette smoke by Martorana, P.A., Beume, R., Lucattelli, M., Wollin, L., Lungarella, G.

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Genetic deficiency of α 1 ‐PI in mice influences lung responses to bleomycin by Cavarra, E., Martorana, P.A., Bartalesi, B., Fineschi, S., Gambelli, F., Lucattelli, M., Ortiz, L., Lungarella, G.

“…It has recently been suggested that proteinase inhibitors modulate the fibrotic response in the lung. This study investigated the development of…”
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