Search Results - "LUCAS, Robert J"

Recommendations for daytime, evening, and nighttime indoor light exposure to best support physiology, sleep, and wakefulness in healthy adults by Brown, Timothy M, Brainard, George C, Cajochen, Christian, Czeisler, Charles A, Hanifin, John P, Lockley, Steven W, Lucas, Robert J, Münch, Mirjam, O'Hagan, John B, Peirson, Stuart N, Price, Luke L A, Roenneberg, Till, Schlangen, Luc J M, Skene, Debra J, Spitschan, Manuel, Vetter, Céline, Zee, Phyllis C, Wright, Jr, Kenneth P

“…Ocular light exposure has important influences on human health and well-being through modulation of circadian rhythms and sleep, as well as neuroendocrine and…”
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Mammalian Inner Retinal Photoreception by Lucas, Robert J.

“…It is now a decade since the first published reports that a small proportion of mammalian retinal ganglion cells are directly photoresponsive. These cells have…”
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Form vision from melanopsin in humans by Allen, Annette E., Martial, Franck P., Lucas, Robert J.

“…Detection and discrimination of spatial patterns is thought to originate with photoreception by rods and cones. Here, we investigated whether the inner-retinal…”
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Melanopsin-Based Brightness Discrimination in Mice and Humans by Brown, Timothy M., Tsujimura, Sei-ichi, Allen, Annette E., Wynne, Jonathan, Bedford, Robert, Vickery, Graham, Vugler, Anthony, Lucas, Robert J.

“…Photoreception in the mammalian retina is not restricted to rods and cones but extends to a small number of intrinsically photoreceptive retinal ganglion cells…”
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Chemogenetic Activation of Melanopsin Retinal Ganglion Cells Induces Signatures of Arousal and/or Anxiety in Mice by Milosavljevic, Nina, Cehajic-Kapetanovic, Jasmina, Procyk, Christopher A., Lucas, Robert J.

“…Functional imaging and psychometric assessments indicate that bright light can enhance mood, attention, and cognitive performance in humans. Indirect evidence…”
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Melanopsin Contributions to the Representation of Images in the Early Visual System by Allen, Annette E., Storchi, Riccardo, Martial, Franck P., Bedford, Robert A., Lucas, Robert J.

“…Melanopsin photoreception enhances retinal responses to variations in ambient light (irradiance) and drives non-image-forming visual reflexes such as circadian…”
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Restoration of Vision with Ectopic Expression of Human Rod Opsin by Cehajic-Kapetanovic, Jasmina, Eleftheriou, Cyril, Allen, Annette E., Milosavljevic, Nina, Pienaar, Abigail, Bedford, Robert, Davis, Katherine E., Bishop, Paul N., Lucas, Robert J.

“…Many retinal dystrophies result in photoreceptor loss, but the inner retinal neurons can survive, making them potentially amenable to emerging optogenetic…”
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Bright daytime light enhances circadian amplitude in a diurnal mammal by Bano-Otalora, Beatriz, Martial, Franck, Harding, Court, Bechtold, David A., Allen, Annette E., Brown, Timothy M., Belle, Mino D. C., Lucas, Robert J.

“…Mammalian circadian rhythms are orchestrated by a master pacemaker in the hypothalamic suprachiasmatic nuclei (SCN), which receives information about the 24 h…”
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Chromatic clocks: Color opponency in non-image-forming visual function by Spitschan, Manuel, Lucas, Robert J., Brown, Timothy M.

“…•As the Earth rotates around it’s own axis, the light environment changes in a predictable fashion in terms of both intensity and spectral composition…”
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Colour as a signal for entraining the mammalian circadian clock by Walmsley, Lauren, Hanna, Lydia, Mouland, Josh, Martial, Franck, West, Alexander, Smedley, Andrew R, Bechtold, David A, Webb, Ann R, Lucas, Robert J, Brown, Timothy M

“…Twilight is characterised by changes in both quantity ("irradiance") and quality ("colour") of light. Animals use the variation in irradiance to adjust their…”
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Melanopsin contributions to irradiance coding in the thalamo-cortical visual system by Brown, Timothy M, Gias, Carlos, Hatori, Megumi, Keding, Sheena R, Semo, Ma'ayan, Coffey, Peter J, Gigg, John, Piggins, Hugh D, Panda, Satchidananda, Lucas, Robert J

“…Photoreception in the mammalian retina is not restricted to rods and cones but extends to a subset of retinal ganglion cells expressing the photopigment…”
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Rods progressively escape saturation to drive visual responses in daylight conditions by Tikidji-Hamburyan, Alexandra, Reinhard, Katja, Storchi, Riccardo, Dietter, Johannes, Seitter, Hartwig, Davis, Katherine E., Idrees, Saad, Mutter, Marion, Walmsley, Lauren, Bedford, Robert A., Ueffing, Marius, Ala-Laurila, Petri, Brown, Timothy M., Lucas, Robert J., Münch, Thomas A.

“…Rod and cone photoreceptors support vision across large light intensity ranges. Rods, active under dim illumination, are thought to saturate at higher…”
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Modulation of Fast Narrowband Oscillations in the Mouse Retina and dLGN According to Background Light Intensity by Storchi, Riccardo, Bedford, Robert A., Martial, Franck P., Allen, Annette E., Wynne, Jonathan, Montemurro, Marcelo A., Petersen, Rasmus S., Lucas, Robert J.

“…Background light intensity (irradiance) substantially impacts the visual code in the early visual system at synaptic and single-neuron levels, but its…”
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Quantitative characterisation of ipRGCs in retinal degeneration using a computation platform for extracting and reconstructing single neurons in 3D from a multi-colour labeled population by Procyk, Christopher A, Rodgers, Jessica, Zindy, Egor, Lucas, Robert J, Milosavljevic, Nina

“…Light has a profound impact on mammalian physiology and behavior. Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment…”
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How rod, cone, and melanopsin photoreceptors come together to enlighten the mammalian circadian clock by Lucas, Robert J, Lall, Gurprit S, Allen, Annette E, Brown, Timothy M

“…In mammals, a small number of retinal ganglion cells express melanopsin, an opsin photopigment, allowing them to be directly photoreceptive. A major function…”
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Two light sensors decode moonlight versus sunlight to adjust a plastic circadian/circalunidian clock to moon phase by Zurl, Martin, Poehn, Birgit, Rieger, Dirk, Krishnan, Shruthi, Rokvic, Dunja, Veedin Rajan, Vinoth Babu, Gerrard, Elliot, Schlichting, Matthias, Orel, Lukas, Ćorić, Aida, Lucas, Robert J, Wolf, Eva, Helfrich-Förster, Charlotte, Raible, Florian, Tessmar-Raible, Kristin

“…Many species synchronize their physiology and behavior to specific hours. It is commonly assumed that sunlight acts as the main entrainment signal for ∼24-h…”
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Melanopsin cells are the principal conduits for rod-cone input to non-image-forming vision by Altimus, Cara M, Zhao, Haiqing, Badea, Tudor C, Yau, King-Wai, Ecker, Jennifer L, Barnard, Alun R, Lall, Gurprit S, Hankins, Mark W, Berson, David M, Haq, Shafiqul, Lucas, Robert J, Güler, Ali D, Hattar, Samer, Liao, Hsi-Wen, Cahill, Hugh

“…Rod and cone photoreceptors detect light and relay this information through a multisynaptic pathway to the brain by means of retinal ganglion cells (RGCs)…”
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A live cell assay of GPCR coupling allows identification of optogenetic tools for controlling Go and Gi signaling by Ballister, Edward R, Rodgers, Jessica, Martial, Franck, Lucas, Robert J

“…Animal opsins are light-sensitive G-protein-coupled receptors (GPCRs) that enable optogenetic control over the major heterotrimeric G-protein signaling…”
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Beyond Lux: methods for species and photoreceptor-specific quantification of ambient light for mammals by McDowell, Richard J, Didikoglu, Altug, Woelders, Tom, Gatt, Mazie J, Moffatt, Finn, Notash, Saba, Hut, Roelof A, Brown, Timothy M, Lucas, Robert J

“…Light is a key environmental regulator of physiology and behaviour. Mistimed or insufficient light disrupts circadian rhythms and is associated with impaired…”
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Appearance of Maxwell’s spot in images rendered using a cyan primary by Gardasevic, Marina, Lucas, Robert J., Allen, Annette E.

“…The discovery of melanopsin as a third type of retinal photoreceptor, contributing to both perceptual vision and reflex light responses, represents a new…”
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