Search Results - "LUCAS, Merlyn J"
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Direct and Indirect Anti-Inflammatory Effects of Tulathromycin in Bovine Macrophages: Inhibition of CXCL-8 Secretion, Induction of Apoptosis, and Promotion of Efferocytosis
Published in Antimicrobial Agents and Chemotherapy (01-03-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Anti-Inflammatory Benefits of Antibiotic-Induced Neutrophil Apoptosis: Tulathromycin Induces Caspase-3-Dependent Neutrophil Programmed Cell Death and Inhibits NF-κB Signaling and CXCL8 Transcription
Published in Antimicrobial Agents and Chemotherapy (01-01-2011)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Tulathromycin Exerts Proresolving Effects in Bovine Neutrophils by Inhibiting Phospholipases and Altering Leukotriene B4, Prostaglandin E2, and Lipoxin A4 Production
Published in Antimicrobial agents and chemotherapy (01-08-2014)“…The accumulation of neutrophils and proinflammatory mediators, such as leukotriene B4 (LTB4), is a classic marker of inflammatory disease. The clearance of…”
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Immunomodulatory effects of tulathromycin on apoptosis, efferocytosis, and proinflammatory leukotriene B4 production in leukocytes from Actinobacillus pleuropneumoniae-or zymosan-challenged pigs
Published in American journal of veterinary research (01-06-2015)“…To investigate the anti-inflammatory and immunomodulatory properties of tulathromycin in vitro and in experimental models of Actinobacillus…”
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Efficacy of a long-acting formulation of ceftiofur crystalline-free acid for the treatment of naturally occurring infectious bovine keratoconjunctivitis
Published in American journal of veterinary research (01-09-2004)“…To evaluate the efficacy of ceftiofur crystalline-free acid (CCFA) administered into the posterior aspect of an ear for treatment of corneal ulceration…”
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New anti‐inflammatory benefits of antibiotics: Tulathromycin promotes apoptosis and efferocytosis, and inhibits pro‐inflammatory CXCL8 production in a model of porcine pleuropneumonia
Published in The FASEB journal (01-04-2013)“…Abstract only Neutrophil (PMN) apoptosis and subsequent clearance by surrounding macrophages (MΦ; efferocytosis) is critical to the resolution of inflammation…”
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Tulathromycin Exerts Proresolving Effects in Bovine Neutrophils by Inhibiting Phospholipases and Altering Leukotriene B 4 , Prostaglandin E 2 , and Lipoxin A 4 Production
Published in Antimicrobial agents and chemotherapy (01-08-2014)“…ABSTRACT The accumulation of neutrophils and proinflammatory mediators, such as leukotriene B 4 (LTB 4 ), is a classic marker of inflammatory disease. The…”
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Tulathromycin promotes phagocytosis and mediates IL‐8, NO, and PGE2 secretion in bovine monocyte‐derived macrophages
Published in The FASEB journal (01-04-2010)“…Tulathromycin (TUL) is an antibiotic used in the treatment of bovine respiratory disease, whose efficacy may be due to anti‐inflammatory capabilities. In the…”
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Evaluation of two antimicrobial therapies in the treatment of Leptospira borgpetersenii serovar hardjo infection in experimentally infected cattle
Published in Veterinary therapeutics (2007)“…This study demonstrated the ability of the antimicrobials tulathromycin (Draxxin) and ceftiofur crystalline free acid sterile suspension (Excede) to clear the…”
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Anti-Inflammatory benefits of antibiotic-induced neutrophil apoptosis: tulathromycin induces caspase-3-dependent neutrophil programmed cell death and inhibits NF-kappaB signaling and CXCL8 transcription
Published in Antimicrobial agents and chemotherapy (01-01-2011)“…Clearance of apoptotic neutrophils is a central feature of the resolution of inflammation. Findings indicate that immuno-modulation and induction of neutrophil…”
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Duration of effectiveness of tulathromycin injectable solution in an Actinobacillus pleuropneumoniae respiratory-disease challenge model in swine
Published in Journal of swine health and production (01-05-2008)“…Objective: To evaluate the duration of effectiveness of a single intramuscular injection of tulathromycin in a swine respiratory-disease challenge model using…”
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Duration of efficacy of ceftiofur crystalline free acid sterile suspension against clinical disease in grower pigs challenged with Actinobacillus pleuropneumoniae
Published in Journal of swine health and production (01-11-2006)“…Objective: To evaluate the duration of efficacy of a single dose of ceftiofur crystalline free acid sterile suspension (CCFA-SS) against clinical disease in…”
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