Search Results - "LUCAS, K. K"

A slip law for glaciers on deformable beds by Zoet, Lucas K, Iverson, Neal R

“…Slip of marine-terminating ice streams over beds of deformable till is responsible for most of the contribution of the West Antarctic Ice Sheet to sea level…”
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Computation of the correlated metal-insulator transition in vanadium dioxide from first principles by Zheng, Huihuo, Wagner, Lucas K

“…Vanadium dioxide (VO2) is a paradigmatic example of a strongly correlated system that undergoes a metal-insulator transition at a structural phase transition…”
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A Balancing Act With Adaptive Hypofractionation by Vitzthum, Lucas K., Pollom, Erqi

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Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain by Horowitz, Alana M, Fan, Xuelai, Bieri, Gregor, Smith, Lucas K, Sanchez-Diaz, Cesar I, Schroer, Adam B, Gontier, Geraldine, Casaletto, Kaitlin B, Kramer, Joel H, Williams, Katherine E, Villeda, Saul A

“…Reversing brain aging may be possible through systemic interventions such as exercise. We found that administration of circulating blood factors in plasma from…”
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Resmetirom for nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled phase 3 trial by Harrison, Stephen A., Taub, Rebecca, Neff, Guy W., Lucas, K. Jean, Labriola, Dominic, Moussa, Sam E., Alkhouri, Naim, Bashir, Mustafa R.

“…Nonalcoholic steatohepatitis (NASH) is a progressive liver disease with no approved treatment. MAESTRO-NAFLD-1 was a 52-week randomized, double-blind,…”
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ASO Author Reflections: A Role for Neoadjuvant Radiation in the Treatment of Locally Advanced Gastric Cancer? by Hui, Caressa, Vitzthum, Lucas K.

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The ambiguous base-pairing and high substrate efficiency of T-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase by Jin, Zhinan, Smith, Lucas K, Rajwanshi, Vivek K, Kim, Baek, Deval, Jerome

“…T-705 (Favipiravir) is a broad-spectrum antiviral molecule currently in late stage clinical development for the treatment of influenza virus infection…”
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Design and Fabrication of a MEMS-Based Break Junction Device for Mechanical Strain-Correlated Optical Characterization of a Single-Molecule by Jeong, Hyunhak, Domulevicz, Lucas K., Hihath, Joshua

“…Here, we propose a robust lab-on-a-chip system for multi-dimensional (electrical, optical, and mechanical) characterization of a single-molecule utilizing a Si…”
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Terahertz transmission vs reflection imaging and model-based characterization for excised breast carcinomas by Bowman, Tyler, El-Shenawee, Magda, Campbell, Lucas K

“…This work presents experimental and analytical comparison of terahertz transmission and reflection imaging modes for assessing breast carcinoma in excised…”
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Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner by Deczkowska, Aleksandra, Matcovitch-Natan, Orit, Tsitsou-Kampeli, Afroditi, Ben-Hamo, Sefi, Dvir-Szternfeld, Raz, Spinrad, Amit, Singer, Oded, David, Eyal, Winter, Deborah R., Smith, Lucas K., Kertser, Alexander, Baruch, Kuti, Rosenzweig, Neta, Terem, Anna, Prinz, Marco, Villeda, Saul, Citri, Ami, Amit, Ido, Schwartz, Michal

“…During ageing, microglia acquire a phenotype that may negatively affect brain function. Here we show that ageing microglial phenotype is largely imposed by…”
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Modularity of the anthropoid dentition: Implications for the evolution of the hominin canine honing complex by Delezene, Lucas K.

“…In most anthropoid primates, the maxillary canine, mandibular canine, and mesial mandibular premolar form a functional complex that hones the canines…”
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Terahertz Imaging of Excised Breast Tumor Tissue on Paraffin Sections by Bowman, Tyler C., El-Shenawee, Magda, Campbell, Lucas K.

“…This paper presents imaging and analysis of heterogeneous breast cancer tissue using pulsed terahertz (THz) imaging technology. The goal of this research is to…”
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Predicting the unpredictable: the regulatory nature and promiscuity of herbicide cross resistance by Bobadilla, Lucas K, Tranel, Patrick J

“…The emergence of herbicide-resistant weeds is a significant threat to modern agriculture. Cross resistance, a phenomenon where resistance to one herbicide…”
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Tissue-Resident Group 2 Innate Lymphoid Cells Differentiate by Layered Ontogeny and In Situ Perinatal Priming by Schneider, Christoph, Lee, Jinwoo, Koga, Satoshi, Ricardo-Gonzalez, Roberto R., Nussbaum, Jesse C., Smith, Lucas K., Villeda, Saul A., Liang, Hong-Erh, Locksley, Richard M.

“…The perinatal period is a critical window for distribution of innate tissue-resident immune cells within developing organs. Despite epidemiologic evidence…”
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TVB-2640 (FASN Inhibitor) for the Treatment of Nonalcoholic Steatohepatitis: FASCINATE-1, a Randomized, Placebo-Controlled Phase 2a Trial by Loomba, Rohit, Mohseni, Rizwana, Lucas, K. Jean, Gutierrez, Julio A., Perry, Robert G., Trotter, James F., Rahimi, Robert S., Harrison, Stephen A., Ajmera, Veeral, Wayne, Jeffrey D., O’Farrell, Marie, McCulloch, William, Grimmer, Katharine, Rinella, Mary, Wai-Sun Wong, Vincent, Ratziu, Vlad, Gores, Gregory J., Neuschwander-Tetri, Brent A., Kemble, George

“…Increased de novo lipogenesis creates excess intrahepatic fat and lipotoxins, propagating liver damage in nonalcoholic steatohepatitis. TVB-2640, a fatty acid…”
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Transient evolution of basal drag during glacier slip by Zoet, Lucas K., Iverson, Neal R., Andrews, Lauren, Helanow, Christian

“…Glacier slip is usually described using steady-state sliding laws that relate drag, slip velocity and effective pressure, but where subglacial conditions vary…”
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Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions by Ho, Theodore T, Dellorusso, Paul V, Verovskaya, Evgenia V, Bakker, Sietske T, Flach, Johanna, Smith, Lucas K, Ventura, Patrick B, Lansinger, Olivia M, Hérault, Aurélie, Zhang, Si Yi, Kang, Yoon-A, Mitchell, Carl A, Villeda, Saul A, Passegué, Emmanuelle

“…While young blood can restore many aged tissues, its effects on the aged blood system itself and old hematopoietic stem cells (HSCs) have not been determined…”
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Dental topography and the diet of Homo naledi by Berthaume, Michael A., Delezene, Lucas K., Kupczik, Kornelius

“…Though late Middle Pleistocene in age, Homo naledi is characterized by a mosaic of Australopithecus-like (e.g., curved fingers, small brains) and Homo-like…”
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A light weight regularization for wave function parameter gradients in quantum Monte Carlo by Pathak, Shivesh, Wagner, Lucas K.

“…The parameter derivative of the expectation value of the energy, ∂E/∂p, is a key ingredient in variational Monte Carlo (VMC) wave function optimization…”
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β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis by Smith, Lucas K, He, Yingbo, Park, Jeong-Soo, Bieri, Gregor, Snethlage, Cedric E, Lin, Karin, Gontier, Geraldine, Wabl, Rafael, Plambeck, Kristopher E, Udeochu, Joe, Wheatley, Elizabeth G, Bouchard, Jill, Eggel, Alexander, Narasimha, Ramya, Grant, Jacqueline L, Luo, Jian, Wyss-Coray, Tony, Villeda, Saul A

“…Circulating β2-microglobulin, a component of MHC I, increases with age, promoting age-related cognitive decline and decreased neurogenesis. Aging drives…”
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