Search Results - "LUCA DE SALVO, Gian"

LKB1 Expression Correlates with Increased Survival in Patients with Advanced Non-Small Cell Lung Cancer Treated with Chemotherapy and Bevacizumab by Bonanno, Laura, De Paoli, Angela, Zulato, Elisabetta, Esposito, Giovanni, Calabrese, Fiorella, Favaretto, Adolfo, Santo, Antonio, Conte, Alessandro Del, Chilosi, Marco, Oniga, Francesco, Sozzi, Gabriella, Moro, Massimo, Ciccarese, Francesco, Nardo, Giorgia, Bertorelle, Roberta, Candiotto, Cinzia, De Salvo, Gian Luca, Amadori, Alberto, Conte, PierFranco, Indraccolo, Stefano

“…LKB1 is a key sensor of metabolic stress, including hypoxia and glucose deprivation, two features of the tumor microenvironment exacerbated by antiangiogenic…”
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Non-metastatic unresected paediatric non-rhabdomyosarcoma soft tissue sarcomas: Results of a pooled analysis from United States and European groups by Ferrari, Andrea, Miceli, Rosalba, Rey, Annie, Oberlin, Odile, Orbach, Daniel, Brennan, Bernadette, Mariani, Luigi, Carli, Modesto, Bisogno, Gianni, Cecchetto, Giovanni, Salvo, Gian Luca De, Casanova, Michela, Vannoesel, Max M, Kelsey, Anna, Stevens, Michael C, Devidas, Meenakshi, Pappo, Alberto S, Spunt, Sheri L

“…Abstract Background Non-rhabdomyosarcoma soft tissue sarcomas (NRSTS) with initially unresected tumours represent a particular subset of patients with a poor…”
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Features predicting unresectability in hepatoblastoma by D'Antiga, Lorenzo, Vallortigara, Francesca, Cillo, Umberto, Talenti, Enrico, Rugge, Massimo, Zancan, Lucia, Dall'Igna, Patrizia, Salvo, Gian Luca De, Perilongo, Giorgio

“…BACKGROUND. Approximately 20% of patients who have hepatoblastoma (HB) still have unresectable disease after preoperative chemotherapy (POC). In these…”
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The impact of survivorship bias in glioblastoma research by Pasqualetti, Francesco, Barberis, Alessandro, Zanotti, Sofia, Montemurro, Nicola, De Salvo, Gian Luca, Soffietti, Riccardo, Mazzanti, Chiara Maria, Ius, Tamara, Caffo, Maria, Paiar, Fabiola, Bocci, Guido, Lombardi, Giuseppe, Harris, Adrian L., Buffa, Francesca M.

“…Despite advances in the therapy of Central Nervous System (CNS) malignancies, treatment of glioblastoma (GB) poses significant challenges due to GB resistance…”
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The predictive role of intolerance of uncertainty and trait of worry in breast cancer patients: A prospective, observational, single-center clinical study by Shams, Malihe, Pardini, Susanna, Del Bianco, Paola, Calabrese, Caterina, De Salvo, Gian Luca, Novara, Caterina

“…Breast cancer diagnosis and treatment compromise well-being in a pervasive way, and negative consequences may remain after recovery. The psychological side of…”
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Sex-related differences in serum biomarker levels predict the activity and efficacy of immune checkpoint inhibitors in advanced melanoma and non-small cell lung cancer patients by Pasello, Giulia, Fabricio, Aline S C, Del Bianco, Paola, Salizzato, Valentina, Favaretto, Adolfo, Piccin, Luisa, Zustovich, Fable, Fabozzi, Alessio, De Rossi, Costanza, Pigozzo, Jacopo, De Nuzzo, Mattia, Cappelletto, Elia, Bonanno, Laura, Palleschi, Dario, De Salvo, Gian Luca, Guarneri, Valentina, Gion, Massimo, Chiarion-Sileni, Vanna

“…Immune Checkpoint Inhibitors (ICIs) lead to durable response and a significant increase in long-term survival in patients with advanced malignant melanoma (MM)…”
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Salvage rates and prognostic factors after relapse in children and adolescents with initially localised synovial sarcoma by Ferrari, Andrea, Salvo, Gian Luca De, Dall’Igna, Patrizia, Meazza, Cristina, Leonardis, Francesco De, Manzitti, Carla, Ioris, Maria Antonietta de, Casanova, Michela, Carli, Modesto, Bisogno, Gianni

“…Abstract Background Previous studies have reported a poor outcome for synovial sarcoma patients whose tumours relapse. Methods This study analysed 44 relapsing…”
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Cutaneous Melanoma in Children and Adolescents: The Italian Rare Tumors in Pediatric Age Project Experience by Ferrari, Andrea, MD, Bisogno, Gianni, MD, Cecchetto, Giovanni, MD, Santinami, Mario, MD, Maurichi, Andrea, MD, Bono, Aldo, MD, Vajna De Pava, Marco, MD, Pierani, Paolo, MD, Bertolini, Patrizia, MD, Rossi, Carlo Riccardo, MD, De Salvo, Gian Luca, MD

“…Objective To describe a series of cutaneous melanoma in children collected by the Italian Rare Tumors in Pediatric Age project. Study design From 2000 to 2012,…”
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A Randomized Clinical Trial on Sentinel Lymph Node Biopsy Versus Axillary Lymph Node Dissection in Breast Cancer : Results of the Sentinella/GIVOM Trial by ZAVAGNO, Giorgio, LUCA DE SALVO, Gian, SCALCO, Giuliano, BOZZA, Fernando, BARUTTA, Luca, DEL BIANCO, Paola, RENIER, Marco, RACANO, Carlo, CARRARO, Paolo, NITTI, Donato

“…The aim of this multicenter randomized trial was to assess the efficacy and safety of sentinel lymph node (SLN) biopsy compared with axillary lymph node…”
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Self-efficacy for coping: utility of the Cancer behavior inventory (Italian) for use in palliative care by Serpentini, Samantha, Del Bianco, Paola, Chirico, Andrea, Merluzzi, Thomas V, Martino, Rosalba, Lucidi, Fabio, De Salvo, Gian Luca, Trentin, Leonardo, Capovilla, Eleonora

“…Newer models of palliative and supportive cancer care view the person as an active agent in managing physical and psychosocial challenges. Therefore, personal…”
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Time to broaden the eligibility criteria in paediatric oncology trials? An analysis of patients with rhabdomyosarcoma non-eligible to the EpSSG RMS2005 trial by Bisogno, Gianni, De Salvo, Gian Luca, Minard-Colin, Veronique, Fajardo, Raquel Davila, Coppadoro, Beatrice, Jenney, Meriel, Ferrari, Andrea, Alvaro, Raquel Hladun, Dall’Igna, Patrizia, Glosli, Heidi, Merks, Johannes H.M.

“…Clinical trials include a series of eligibility and exclusion criteria that define the study population to reduce inter-patient heterogeneity and increase…”
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Survivin expression and prognostic significance in pediatric malignant peripheral nerve sheath tumors (MPNST) by Alaggio, Rita, Turrini, Riccardo, Boldrin, Daniela, Merlo, Anna, Gambini, Claudio, Ferrari, Andrea, Dall'igna, Patrizia, Coffin, Cheryl M, Martines, Annalisa, Bonaldi, Laura, De Salvo, Gian Luca, Zanovello, Paola, Rosato, Antonio

“…Malignant peripheral nerve sheath tumors (MPNST) are very aggressive malignancies comprising approximately 5-10% of all soft tissue sarcomas. In this study, we…”
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Local staging and treatment in extremity rhabdomyosarcoma. A report from the EpSSG‐RMS2005 study by Terwisscha van Scheltinga, Sheila E. J., Wijnen, Marc H. W. A., Martelli, Hélène, Rogers, Timothy, Mandeville, Henry, Gaze, Mark N., McHugh, Keiran, Corradini, Nadege, Orbach, Daniel, Jenney, Meriel, Kelsey, Anna, Chisholm, Julia, Gallego, Soledad, Glosli, Heidi, Ferrari, Andrea, Zanetti, Ilaria, De Salvo, Gian Luca, Minard‐Colin, Veronique, Bisogno, Giani, van Noesel, Max M., Merks, Hans H. M.

“…Rhabdomyosarcoma of the extremities present with two main challenges: correct evaluation of initial regional nodal involvement and define adequate local…”
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Genomic complexity in pediatric synovial sarcomas (Synobio study): the European pediatric soft tissue sarcoma group (EpSSG) experience by Orbach, Daniel, Mosseri, Véronique, Pissaloux, Daniel, Pierron, Gaelle, Brennan, Bernadette, Ferrari, Andrea, Chibon, Frederic, Bisogno, Gianni, De Salvo, Gian Luca, Chakiba, Camille, Corradini, Nadège, Minard‐Colin, Véronique, Kelsey, Anna, Ranchère‐Vince, Dominique

“…A genomic index (GI) tool using array comparative genomic hybridization (aCGH) on tumor cells has emerged as independent prognostic factor associated with the…”
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Association Between MDM2–SNP309 and Age at Colorectal Cancer Diagnosis According to p53 Mutation Status by Menin, Chiara, Scaini, Maria Chiara, De Salvo, Gian Luca, Biscuola, Martina, Quaggio, Monica, Esposito, Giovanni, Belluco, Claudio, Montagna, Marco, Agata, Simona, D'Andrea, Emma, Nitti, Donato, Amadori, Alberto, Bertorelle, Roberta

“…A single-nucleotide polymorphism (SNP) in the promoter of the MDM2 gene, SNP309 (a T→G change), was recently implicated in the early onset of cancer in…”
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Curative surgery for obstruction from primary left colorectal carcinoma: primary or staged resection? by De Salvo, G L, Gava, C, Pucciarelli, S, Lise, M

“…In 8 to 29% of patients with colorectal carcinoma, obstruction is the main symptom at diagnosis, and 85% of patients undergoing emergency colorectal surgery…”
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Factors Predictive of Nonsentinel Lymph Node Involvement and Clinical Outcome in Melanoma Patients With Metastatic Sentinel Lymph Node by Rossi, Carlo Riccardo, Luca De Salvo, Gian, Bonandini, Elena, Mocellin, Simone, Foletto, Mirto, Pasquali, Sandro, Pilati, Pierluigi, Lise, Mario, Nitti, Donato, Rizzo, Elisa, Cristina Montesco, Maria

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The role of ultrasound of sentinel nodes in the pre- and post-operative evaluation of stage I melanoma patients by Testori, Alessandro, Lazzaro, Gianluca, Baldini, Federica, Tosti, Giulio, Mosconi, Massimo, Lovati, Elena, Bossi, Chiara, Sanvito, Stefania, Stanganelli, Ignazio, Mazzarol, Giovanni, De Salvo, Gian Luca, Trifirò, Giuseppe, Biffi, Roberto, Bellomi, Massimo

“…We have investigated the role of high-resolution ultrasound (US) in the analysis of sentinel node(s) in melanoma patients in pre-operative staging and…”
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Tolerability of intensified intravenous interferon alfa-2b versus the ECOG 1684 schedule as adjuvant therapy for stage III melanoma: a randomized phase III Italian Melanoma Inter-group trial (IMI - Mel.A.) [ISRCTN75125874] by Chiarion-Sileni, Vanna, Del Bianco, Paola, Romanini, Antonella, Guida, Michele, Paccagnella, Adriano, Dalla Palma, Maurizio, Naglieri, Emanuele, Ridolfi, Ruggero, Silvestri, Barbara, Michiara, Maria, De Salvo, Gian Luca

“…High-dose interferon alfa-2b (IFNalfa-2b), according to the ECOG 1684 schedule, is the only approved adjuvant treatment for stage III melanoma patients by the…”
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Regorafenib compared with lomustine in patients with relapsed glioblastoma (REGOMA): a multicentre, open-label, randomised, controlled, phase 2 trial by Lombardi, Giuseppe, De Salvo, Gian Luca, Brandes, Alba Ariela, Eoli, Marica, Rudà, Roberta, Faedi, Marina, Lolli, Ivan, Pace, Andrea, Daniele, Bruno, Pasqualetti, Francesco, Rizzato, Simona, Bellu, Luisa, Pambuku, Ardi, Farina, Miriam, Magni, Giovanna, Indraccolo, Stefano, Gardiman, Marina Paola, Soffietti, Riccardo, Zagonel, Vittorina

“…Glioblastoma is a highly vascularised tumour and there are few treatment options after disease recurrence. Regorafenib is an oral multikinase inhibitor of…”
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