Search Results - "LUBENOW, N"
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Heparin‐induced thrombocytopenia: a prospective study on the incidence, platelet‐activating capacity and clinical significance of antiplatelet factor 4/heparin antibodies of the IgG, IgM, and IgA classes
Published in Journal of thrombosis and haemostasis (01-08-2007)“…Introduction: Platelet‐activating antiplatelet factor 4/heparin (anti‐PF4/heparin) antibodies are the major cause of heparin‐induced thrombocytopenia (HIT)…”
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Lepirudin in patients with heparin‐induced thrombocytopenia – results of the third prospective study (HAT‐3) and a combined analysis of HAT‐1, HAT‐2, and HAT‐3
Published in Journal of thrombosis and haemostasis (01-11-2005)“…Objectives: To assess efficacy and safety of lepirudin in patients with heparin‐induced thrombocytopenia (HIT) in a prospective study (HAT‐3) as well as in a…”
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Anaphylactic and anaphylactoid reactions associated with lepirudin in patients with heparin-induced thrombocytopenia
Published in Circulation (New York, N.Y.) (28-10-2003)“…Lepirudin (Refludan) is a hirudin derivative. It is a direct thrombin inhibitor obtained by recombinant technology from the medicinal leech and is approved for…”
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Predonation finger lancet punctures: a potential risk factor for interdonor pathogen transmission in the blood donor clinic
Published in Vox sanguinis (01-07-2016)“…Background and Objectives Point‐of‐care testing using capillary blood from a finger prick is widely used for predonation haemoglobin testing of blood donors…”
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Heparin‐induced thrombocytopenia: towards standardization of platelet factor 4/heparin antigen tests
Published in Journal of thrombosis and haemostasis (01-09-2010)“…Background: Laboratory confirmation of heparin‐induced thrombocytopenia (HIT) is based on detection of heparin‐dependent platelet‐activating antibodies…”
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Inadequate prophylactic effect of low-molecular weight heparin in critically ill COVID-19 patients
Published in Journal of critical care (01-12-2020)“…The aim of this study was to investigate potential markers of coagulopathy and the effects of thromboprophylaxis with low-molecular-weight heparin (LMWH) on…”
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Motivational factors for blood donation in first‐time donors and repeat donors: a cross‐sectional study in West Pomerania
Published in Transfusion medicine (Oxford, England) (01-12-2017)“…Summary Objectives This study aimed to analyse motivational factors for blood donation in different donor groups. Background As the demographic change will…”
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Heparin-induced thrombocytopenia with thromboembolic complications: meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range
Published in Blood (01-08-2000)“…This meta-analysis focuses on 2 prospective studies in patients with heparin-induced thrombocytopenia (HIT) and thromboembolic complication (TEC) who were…”
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IgG classification of anti‐PF4/heparin antibodies to identify patients with heparin‐induced thrombocytopenia during mechanical circulatory support
Published in Journal of thrombosis and haemostasis (01-02-2007)“…Commercial immunoassays frequently detect anti‐PF4/heparin antibodies during mechanical circulatory support (MCS), but only a small minority of patients…”
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Prophylactic platelet transfusions
Published in Vox sanguinis (01-08-2012)Get full text
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Heparin-induced thrombocytopenia: recommendations for optimal use of recombinant hirudin
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01-08-2000)“…Recombinant hirudins have a definite role in the treatment of patients with heparin-induced thrombocytopenia (HIT). The most important adverse effects are…”
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Management of patients with heparin-induced thrombocytopenia: focus on recombinant hirudin
Published in Journal of thrombosis and thrombolysis (01-11-2000)Get full text
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Drug-induced and drug-dependent immune thrombocytopenias
Published in Reviews in clinical and experimental hematology (01-09-2001)“…Thrombocytopenia is a frequent comorbid condition in many in hospital patients. In some patients, drugs are the cause of low platelet counts. While cytotoxic…”
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Standardizing the freeze‐thaw preparation of growth factors from platelet lysate
Published in Transfusion (Philadelphia, Pa.) (01-04-2017)“…BACKGROUND Over the past decades, the focus on the regenerative properties of platelets (PLTs) has intensified and many PLT‐derived growth factors are readily…”
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Patterns of blood use in Sweden from 2008 to 2017: A nationwide cohort study
Published in Transfusion (Philadelphia, Pa.) (01-11-2020)“…Background Transfusion patterns in Sweden have not been characterized on a nationwide level. Study Design and Methods We conducted a nationwide descriptive…”
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Lepirudin for prophylaxis of thrombosis in patients with acute isolated heparin-induced thrombocytopenia: an analysis of 3 prospective studies
Published in Blood (15-11-2004)“…This analysis of 3 prospective multicenter trials in patients with laboratory-confirmed acute heparin-induced thrombocytopenia (HIT) without clinically evident…”
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Rational design of new CpG oligonucleotides that combine B cell activation with high IFN‐α induction in plasmacytoid dendritic cells
Published in European journal of immunology (01-06-2003)“…Two different types of CpG motif‐containing oligonucleotides (CpG ODN) have been described: CpG‐A with high induction of IFN‐α in plasmacytoid dendritic cells;…”
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Recombinant hirudin in clinical practice : Focus on lepirudin
Published in Circulation (New York, N.Y.) (13-03-2001)“…Clinical applications for recombinant hirudins have been investigated for the past 10 years. The first indication for which a hirudin-lepirudin-has been…”
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