Search Results - "LUBDA, Dieter"

Use of Polyvinyl Alcohol as a Solubility-Enhancing Polymer for Poorly Water Soluble Drug Delivery (Part 1) by Brough, Chris, Miller, Dave A., Keen, Justin M., Kucera, Shawn A., Lubda, Dieter, Williams, Robert O.

“…Polyvinyl alcohol (PVAL) has not been investigated in a binary formulation as a concentration-enhancing polymer owing to its high melting point/high viscosity…”
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Enabling thermal processing of ritonavir–polyvinyl alcohol amorphous solid dispersions by KinetiSol® Dispersing by LaFountaine, Justin S., Jermain, Scott V., Prasad, Leena Kumari, Brough, Chris, Miller, Dave A., Lubda, Dieter, McGinity, James W., Williams, Robert O.

“…[Display omitted] Polyvinyl alcohol has received little attention as a matrix polymer in amorphous solid dispersions (ASDs) due to its thermal and rheological…”
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Chirally functionalized anion-exchange type silica monolith for enantiomer separation of 2-aryloxypropionic acid herbicides by non-aqueous capillary electrochromatography by Buchinger, Stefanie, Follrich, Beatrix, Lämmerhofer, Michael, Lubda, Dieter, Lindner, Wolfgang

“…A silica based monolithic capillary column derivatized with O-9-(tert-butylcarbamoyl)quinidine was prepared for CEC enantiomer separation of chiral…”
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Pore structural characterization of monolithic silica columns by inverse size-exclusion chromatography by Grimes, Brian A., Skudas, Romas, Unger, Klaus K., Lubda, Dieter

“…In this work, a parallel pore model (PPM) and a pore network model (PNM) are developed to provide a state-of-art method for the calculation of several…”
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Bio-compatible in-tube solid-phase microextraction capillary for the direct extraction and high-performance liquid chromatographic determination of drugs in human serum by Mullett, Wayne M, Levsen, Karsten, Lubda, Dieter, Pawliszyn, Janusz

“…A restricted access material (RAM), alkyl-diol-silica (ADS), was used to prepare a highly bio-compatible solid-phase microextraction (SPME) capillary for the…”
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Monolithic silica columns of various format in automated sample clean-up/multidimensional liquid chromatography/mass spectrometry for peptidomics by Machtejevas, Egidijus, Andrecht, Sven, Lubda, Dieter, Unger, Klaus K.

“…The following particulate and monolithic silica columns were implemented in a fully automated and flexible multidimensional LC/MS system with integrated sample…”
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Alkyl diol silica: restricted access pre-column packings for fast liquid chromatography-integrated sample preparation of biological fluids by Schäfer, Christian, Lubda, Dieter

“…A silica-based pre-column packed with a ‘restricted access material’ was used for fully automated solid-phase extraction of drugs and metabolites from…”
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Combining restricted access material (RAM) and turbulent flow for the rapid on-line extraction of the cyclooxygenase-2 inhibitor rofecoxib in plasma samples by Vintiloiu, Anda, Mullett, Wayne M., Papp, Robert, Lubda, Dieter, Kwong, Elizabeth

“…Restricted access material (RAM) has been used in the packing of a solid-phase extraction (SPE) column for on-line extractions under turbulent flow conditions…”
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SilicaROD™ — A new challenge in fast high-performance liquid chromatography separations by Cabrera, Karin, Wieland, Gerhard, Lubda, Dieter, Nakanishi, Kazuki, Soga, Naohiro, Minakuchi, Hiroyoshi, Unger, Klaus K

“…High performance liquid chromatography (HPLC) has become one of the most used methods for the analysis of compound mixtures in industry, especially for the…”
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Poly (vinyl alcohol) microneedles: Fabrication, characterization, and application for transdermal drug delivery of doxorubicin by Nguyen, Hiep X., Bozorg, Behnam Dasht, Kim, Yujin, Wieber, Alena, Birk, Gudrun, Lubda, Dieter, Banga, Ajay K.

“…[Display omitted] Poly (vinyl alcohol) microneedles were fabricated, characterized, and applied to enhance in vitro transdermal delivery of doxorubicin. The…”
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Evaluation and comparison of tailor-made stationary phases based on spherical silica-based beads for capillary electrochromatography via peptide separation analysis by Huber, M.I., Hennessy, T.P., Lubda, Dieter, Unger, K.K.

“…Small cyclic peptides have been employed to elucidate the performance of novel sorbents as stationary phases in capillary electrochromatography (CEC). In this…”
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Mesoporous silica-based dosage forms improve release characteristics of poorly soluble drugs: case example fenofibrate by Dressman, Jennifer B., Herbert, Elisabeth, Wieber, Alena, Birk, Gudrun, Saal, Christoph, Lubda, Dieter

“…Objectives Mesoporous silica‐based dosage forms offer the potential for improving the absorption of poorly soluble drugs after oral administration. In this…”
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Chiral capillary liquid chromatography based on penicillin G acylase immobilized on monolithic epoxy silica column by Gotti, Roberto, Fiori, Jessica, Calleri, Enrica, Temporini, Caterina, Lubda, Dieter, Massolini, Gabriella

“…► Penicillin G acylase has been immobilized on a silica monolithic capillary column. ► Capillary liquid chromatography (CLC) has been performed using CE…”
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Development and evaluation of a polyvinyl alcohol based topical gel by Sivaraman, Arunprasad, Ganti, Sindhu S., Nguyen, Hiep X., Birk, Gudrun, Wieber, Alena, Lubda, Dieter, Banga, Ajay K.

“…Topical drug delivery systems provide localized drug action. A hydrophilic polymer such as polyvinyl alcohol is a multi-faceted excipient that can be used as a…”
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Mesoporous silica‐based dosage forms improve bioavailability of poorly soluble drugs in pigs: case example fenofibrate by O'Shea, Joseph P., Nagarsekar, Kalpa, Wieber, Alena, Witt, Vanessa, Herbert, Elisabeth, O'Driscoll, Caitriona M., Saal, Christoph, Lubda, Dieter, Griffin, Brendan T., Dressman, Jennifer B.

“…Objectives Mesoporous silicas (SLC) have demonstrated considerable potential to improve bioavailability of poorly soluble drugs by facilitating rapid…”
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Use of Polyvinyl Alcohol as a Solubility Enhancing Polymer for Poorly Water-Soluble Drug Delivery (Part 2) by Brough, Chris, Miller, Dave A., Ellenberger, Daniel, Lubda, Dieter, Williams, Robert O.

“…The KinetiSol® Dispersing (KSD) technology has enabled the investigation into the use of polyvinyl alcohol (PVAL) as a concentration enhancing polymer for…”
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Monolithic silica-based capillary column with strong chiral cation-exchange type surface modification for enantioselective non-aqueous capillary electrochromatography by Preinerstorfer, Beatrix, Lubda, Dieter, Lindner, Wolfgang, Lämmerhofer, Michael

“…A silica-based monolithic stationary phase prepared by the sol–gel process in a 100 μm I.D. fused-silica (FS) capillary has been modified chemically with…”
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Pronase-Immobilized Enzyme Reactor: an Approach for Automation in Glycoprotein Analysis by LC/LC−ESI/MSn by TEMPORINI, Caterina, PERANI, Eleonora, CALLERI, Enrica, DOLCINI, Lorenzo, LUBDA, Dieter, CACCIALANZA, Gabriele, MASSOLINI, Gabriella

“…An automated analytical approach is proposed for simultaneous characterization of glycan and peptide moieties in pronase-generated glycopeptides. The proposed…”
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Stir bar sorptive extraction based on restricted access material for the direct extraction of caffeine and metabolites in biological fluids by Lambert, Jean-Philippe, Mullett, Wayne M., Kwong, Elizabeth, Lubda, Dieter

“…A biocompatible stir bar sorptive extraction (SBSE) device was prepared using an alkyl-diol-silica (ADS) restricted access material (RAM) as the SBSE coating…”
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Monolithic silica columns with chemically bonded tert-butylcarbamoylquinine chiral anion-exchanger selector as a stationary phase for enantiomer separations by Lubda, Dieter, Lindner, Wolfgang

“…An enantioselective silica rod type chiral stationary phase (CSP) is presented as a novel combination of the well-known enantiomer separation properties of…”
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