Search Results - "LUBBERINK, Mark"
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Kinetic Models for Measuring P-glycoprotein Function at the Blood-Brain Barrier with Positron Emission Tomography
Published in Current pharmaceutical design (01-01-2016)“…P-glycoprotein function is associated with a number of neurodegenerative and psychiatric diseases as well as with pharmacoresistance to for example…”
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Studies of a Next-Generation Silicon-Photomultiplier-Based Time-of-Flight PET/CT System
Published in Journal of Nuclear Medicine (01-09-2017)“…This article presents system performance studies for the Discovery MI PET/CT system, a new time-of-flight system based on silicon photomultipliers. System…”
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EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging
Published in European journal of nuclear medicine and molecular imaging (01-04-2021)“…The use of cardiac PET, and in particular of quantitative myocardial perfusion PET, has been growing during the last years, because scanners are becoming…”
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Measuring HER2-Receptor Expression In Metastatic Breast Cancer Using [68Ga]ABY-025 Affibody PET/CT
Published in Theranostics (2016)“…Positron Emission Tomography (PET) imaging of HER2 expression could potentially be used to select patients for HER2-targed therapy, predict response based on…”
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Clinical quantitative cardiac imaging for the assessment of myocardial ischaemia
Published in Nature reviews cardiology (01-07-2020)“…Cardiac imaging has a pivotal role in the prevention, diagnosis and treatment of ischaemic heart disease. SPECT is most commonly used for clinical myocardial…”
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Position paper of the EACVI and EANM on artificial intelligence applications in multimodality cardiovascular imaging using SPECT/CT, PET/CT, and cardiac CT
Published in European journal of nuclear medicine and molecular imaging (01-05-2021)“…In daily clinical practice, clinicians integrate available data to ascertain the diagnostic and prognostic probability of a disease or clinical outcome for…”
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Journal Article Web Resource -
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Application of positron emission tomography in psychiatry—methodological developments and future directions
Published in Translational psychiatry (14-06-2022)“…Mental disorders represent an increasing source of disability and high costs for societies globally. Molecular imaging techniques such as positron emission…”
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Diagnostic Accuracy of [11C]PIB Positron Emission Tomography for Detection of Cardiac Amyloidosis
Published in JACC. Cardiovascular imaging (01-06-2020)“…This dual-site study evaluated the diagnostic accuracy of the method. Pittsburgh compound ([11C]PIB) positron emission tomography (PIB-PET) has shown promise…”
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Rapid Decrease in Delivery of Chemotherapy to Tumors after Anti-VEGF Therapy: Implications for Scheduling of Anti-Angiogenic Drugs
Published in Cancer cell (17-01-2012)“…Current strategies combining anti-angiogenic drugs with chemotherapy provide clinical benefit in cancer patients. It is assumed that anti-angiogenic drugs,…”
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Blood-brain barrier P-glycoprotein function in Alzheimer's disease
Published in Brain (London, England : 1878) (01-01-2012)“…A major pathological hallmark of Alzheimer's disease is accumulation of amyloid-β in senile plaques in the brain. Evidence is accumulating that decreased…”
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Nuclear medicine in the assessment and prevention of cancer therapy-related cardiotoxicity: prospects and proposal of use by the European Association of Nuclear Medicine (EANM)
Published in European journal of nuclear medicine and molecular imaging (01-02-2023)“…Cardiotoxicity may present as (pulmonary) hypertension, acute and chronic coronary syndromes, venous thromboembolism, cardiomyopathies/heart failure,…”
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Automatic generation of absolute myocardial blood flow images using [15O]H2O and a clinical PET/CT scanner
Published in European journal of nuclear medicine and molecular imaging (01-05-2011)“…Purpose Parametric imaging of absolute myocardial blood flow (MBF) using [ 15 O]H 2 O enables determination of MBF with high spatial resolution. The aim of…”
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Acute nicotine exposure blocks aromatase in the limbic brain of healthy women: A [11C]cetrozole PET study
Published in Comprehensive psychiatry (01-05-2023)“…Of interest to women's mental health, a wealth of studies suggests sex differences in nicotine addiction and treatment response, but their psychoneuroendocrine…”
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PET/MRI of glucose metabolic rate, lipid content and perfusion in human brown adipose tissue
Published in Scientific reports (22-07-2021)“…This study evaluated the MRI-derived fat fraction (FF), from a Cooling-reheating protocol, for estimating the cold-induced brown adipose tissue (BAT) metabolic…”
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Parametric imaging and quantitative analysis of the PET amyloid ligand [18F]flutemetamol
Published in NeuroImage (Orlando, Fla.) (01-11-2015)“…The amyloid imaging PET tracer [18F]flutemetamol was recently approved by regulatory authorities in the US and EU for estimation of β-amyloid neuritic plaque…”
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Procedural recommendations of cardiac PET/CT imaging: standardization in inflammatory-, infective-, infiltrative-, and innervation- (4Is) related cardiovascular diseases: a joint collaboration of the EACVI and the EANM: summary
Published in European heart journal cardiovascular imaging (01-12-2020)“…Abstract With this summarized document we share the standard for positron emission tomography (PET)/(diagnostic)computed tomography (CT) imaging procedures in…”
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Tracer Kinetic Analysis of (S)-¹⁸F-THK5117 as a PET Tracer for Assessing Tau Pathology
Published in The Journal of nuclear medicine (1978) (01-04-2016)“…Because a correlation between tau pathology and the clinical symptoms of Alzheimer disease (AD) has been hypothesized, there is increasing interest in…”
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Effects of Hepatic Triglyceride Content on Myocardial Metabolism in Type 2 Diabetes
Published in Journal of the American College of Cardiology (13-07-2010)“…Objectives The purpose of this study was to investigate the relationship between hepatic triglyceride content and both myocardial function and metabolism in…”
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Quantification of aromatase binding in the female human brain using [11C]cetrozole positron emission tomography
Published in Journal of neuroscience research (01-11-2020)“…Aromatase, the enzyme that in the brain converts testosterone and androstenedione to estradiol and estrone, respectively, is a putative key factor in…”
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Image reconstruction methods affect software-aided assessment of pathologies of [18F]flutemetamol and [18F]FDG brain-PET examinations in patients with neurodegenerative diseases
Published in NeuroImage clinical (01-01-2020)“…•[18F]Flutemetamol and [18F]FDG image reconstruction.•Software-aided assessment of neurodegenerative disease patients.•New developments in brain PET image…”
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