Search Results - "LOWENBERG, B"

Comparative value of post-remission treatment in cytogenetically normal AML subclassified by NPM1 and FLT3-ITD allelic ratio by Versluis, J, in ‘t Hout, F E M, Devillier, R, van Putten, W L J, Manz, M G, Vekemans, M -C, Legdeur, M -C, Passweg, J R, Maertens, J, Kuball, J, Biemond, B J, Valk, P J M, van der Reijden, B A, Meloni, G, Schouten, H C, Vellenga, E, Pabst, T, Willemze, R, Löwenberg, B, Ossenkoppele, G, Baron, F, Huls, G, Cornelissen, J J

“…Post-remission treatment (PRT) in patients with cytogenetically normal (CN) acute myeloid leukemia (AML) in first complete remission (CR1) is debated. We…”
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The prognostic relevance of miR-212 expression with survival in cytogenetically and molecularly heterogeneous AML by Sun, S M, Rockova, V, Bullinger, L, Dijkstra, M K, Döhner, H, Löwenberg, B, Jongen-Lavrencic, M

“…Acute myeloid leukemia (AML) is a highly heterogeneous disease, characterized by various cytogenetic and molecular abnormalities, many of which may express…”
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Comparative therapeutic value of post-remission approaches in patients with acute myeloid leukemia aged 40–60 years by Cornelissen, J J, Versluis, J, Passweg, J R, van Putten, W L J, Manz, M G, Maertens, J, Beverloo, H B, Valk, P J M, van Marwijk Kooy, M, Wijermans, P W, Schaafsma, M R, Biemond, B J, Vekemans, M-C, Breems, D A, Verdonck, L F, Fey, M F, Jongen-Lavrencic, M, Janssen, J J W M, Huls, G, Kuball, J, Pabst, T, Graux, C, Schouten, H C, Gratwohl, A, Vellenga, E, Ossenkoppele, G, Löwenberg, B

“…The preferred type of post-remission therapy (PRT) in patients with acute myeloid leukemia (AML) in first complete remission (CR1) is a subject of continued…”
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Expression of a passenger miR-9 predicts favorable outcome in adults with acute myeloid leukemia less than 60 years of age by Nowek, K, Sun, S M, Dijkstra, M K, Bullinger, L, Döhner, H, Erkeland, S J, Löwenberg, B, Jongen-Lavrencic, M

“…In double-stranded miRNA/miRNA* duplexes, one of the strands represents an active miRNA, whereas another, known as a passenger strand (miRNA*), is typically…”
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MicroRNA-155 induces AML in combination with the loss of C/EBPA in mice by Alemdehy, M F, de Looper, H W J, Kavelaars, F G, Sanders, M A, Hoogenboezem, R, Löwenberg, B, Valk, P J M, Touw, I P, Erkeland, S J

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PU.1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway by Zhou, J, Wu, J, Li, B, Liu, D, Yu, J, Yan, X, Zheng, S, Wang, J, Zhang, L, Zhang, L, He, F, Li, Q, Chen, A, Zhang, Y, Zhao, X, Guan, Y, Zhao, X, Yan, J, Ni, J, Nobrega, M A, Löwenberg, B, Delwel, R, Valk, P J M, Kumar, A, Xie, L, Tenen, D G, Huang, G, Wang, Q-f

“…Mixed lineage leukemia (MLL) fusion proteins directly activate the expression of key downstream genes such as MEIS1 , HOXA9 to drive an aggressive form of…”
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Acquired mutations in ASXL1 in acute myeloid leukemia: prevalence and prognostic value by Pratcorona, M., Abbas, S., Sanders, M. A., Koenders, J. E., Kavelaars, F. G., Erpelinck-Verschueren, C. A. J., Zeilemakers, A., Lowenberg, B., Valk, P. J. M.

“…Somatic mutations in the additional sex comb-like 1 (ASXL1) gene have been described in various types of myeloid malignancies, including acute myeloid…”
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Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling by Verhaak, Roel G.W, Wouters, Bas J, Erpelinck, Claudia A.J, Abbas, Saman, Beverloo, H. Berna, Lugthart, Sanne, Lowenberg, Bob, Delwel, Ruud, Valk, Peter J.M

“…1 Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands 2 Department of Medical Oncology, Dana-Farber Cancer Institute,…”
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Efficacy and Safety of Gemtuzumab Ozogamicin in Patients With CD33-Positive Acute Myeloid Leukemia in First Relapse by SIEVERS, Eric L, LARSON, Richard A, BERGER, Mark S, ETEN, Catharine B, LOKEN, Michael R, VAN DONGEN, Jacques J. M, BERNSTEIN, Irwin D, APPELBAUM, Frederick R, STADTMAUER, Edward A, ESTEY, Elihu, LÖWENBERG, Bob, DOMBRET, Hervé, KARANES, Chatchada, THEOBALD, Matthias, BENNETT, John M, SHERMAN, Matthew L

“…Three open-label, multicenter trials were conducted to evaluate the efficacy and safety of single-agent Mylotarg (gemtuzumab ozogamicin; CMA-676; Wyeth…”
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Report of an international working group to standardize response criteria for myelodysplastic syndromes by Cheson, Bruce D., Bennett, John M., Kantarjian, Hagop, Pinto, Antonio, Schiffer, Charles A., Nimer, Stephen D., Löwenberg, Bob, Beran, Miroslav, de Witte, Theo M., Stone, Richard M., Mittelman, Moshe, Sanz, Guillermo F., Wijermans, Pierre W., Gore, Steven, Greenberg, Peter L.

“…Standardized criteria for assessing response are essential to ensure comparability among clinical trials for patients with myelodysplastic syndromes (MDS). An…”
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Autologous hematopoietic stem cell transplantation for autoimmune diseases by Gratwohl, A, Passweg, J, Bocelli-Tyndall, C, Fassas, A, van Laar, J M, Farge, D, Andolina, M, Arnold, R, Carreras, E, Finke, J, Kötter, I, Kozak, T, Lisukov, I, Löwenberg, B, Marmont, A, Moore, J, Saccardi, R, Snowden, J A, van den Hoogen, F, Wulffraat, N M, Zhao, X W, Tyndall, A

“…Experimental data and early phase I/II studies suggest that high-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (HSCT) can…”
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Biological characteristics and prognosis of adult acute myeloid leukemia with internal tandem duplications in the Flt3 gene by ROMBOUTS, W. J. C, BLOKLAND, I, LÖWENBERG, B, PLOEMACHER, R. E

“…Internal tandem duplications of the FIt3 gene (FIt3/ITDs) are present in about 18% of all AML cases and are therefore one of the most frequent somatic gene…”
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Mutant Wilms' tumor 1 ( ) mRNA with premature termination codons in acute myeloid leukemia (AML) is sensitive to nonsense-mediated RNA decay (NMD) by Abbas, S, Erpelinck-Verschueren, C A J, Goudswaard, C S, Löwenberg, B, Valk, P J M

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8 Acute myeloid leukemia by Lowenberg, B

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OP06 Gene-expression micro-array in AML diagnostics by Lowenberg, B

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Resistance prediction in AML: analysis of 4601 patients from MRC/NCRI, HOVON/SAKK, SWOG and MD Anderson Cancer Center by Walter, R B, Othus, M, Burnett, A K, Löwenberg, B, Kantarjian, H M, Ossenkoppele, G J, Hills, R K, Ravandi, F, Pabst, T, Evans, A, Pierce, S R, Vekemans, M-C, Appelbaum, F R, Estey, E H

“…Therapeutic resistance remains the principal problem in acute myeloid leukemia (AML). We used area under receiver-operating characteristic curves (AUCs) to…”
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Tetramer-based quantification of cytomegalovirus (CMV)–specific CD8+ T lymphocytes in T-cell–depleted stem cell grafts and after transplantation may identify patients at risk for progressive CMV infection by Gratama, Jan W., van Esser, Joost W.J., Lamers, Cor H.J., Tournay, Claire, Löwenberg, Bob, Bolhuis, Reinder L.H., Cornelissen, Jan J.

“…Recovery of cytomegalovirus (CMV)–specific T-cell–mediated immunity after allogeneic hematopoietic stem cell transplantation (SCT) is critical for protection…”
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Unrelated marrow transplantation for adult patients with poor-risk acute lymphoblastic leukemia: strong graft-versus-leukemia effect and risk factors determining outcome by Cornelissen, Jan J., Carston, Michael, Kollman, Craig, King, Roberta, Dekker, Adriaan W., Löwenberg, Bob, Anasetti, Claudio

“…Between 1988 and 1999, 127 patients with poor-risk acute lymphoblastic leukemia (ALL) received a matched unrelated donor transplant using marrow procured by…”
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An Efficient Design for Cost-Effectiveness Studies of Personalized Medicine Strategies by Leunis, A, Redekop, W.K, Lowenberg, B, Uyl-De Groot, C.A

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Epstein-Barr virus (EBV) reactivation is a frequent event after allogeneic stem cell transplantation (SCT) and quantitatively predicts EBV-lymphoproliferative disease following T-cell–depleted SCT by van Esser, Joost W.J., van der Holt, Bronno, Meijer, Ellen, Niesters, Hubert G.M., Trenschel, Rudolf, Thijsen, Steven F.T., van Loon, Anton M., Frassoni, Francesco, Bacigalupo, Andrea, Schaefer, Ulrich W., Osterhaus, Albert D.M.E., Gratama, Jan Willem, Löwenberg, Bob, Verdonck, Leo F., Cornelissen, Jan J.

“…Reactivation of the Epstein-Barr virus (EBV) after allogeneic stem cell transplantation (allo-SCT) may evoke a protective cellular immune response or may be…”
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