Search Results - "LOVEGROVE, J. U"

C-antineutrophil cytoplasmic antibody positivity in vasculitis patients is associated with the Z allele of alpha-1-antitrypsin, and P-antineutrophil cytoplasmic antibody positivity with the S allele by GRIFFITH, M. E, LOVEGROVE, J. U, GASKIN, G, WHITEHOUSE, D. B, PUSEY, C. D

“…Antineutrophil cytoplasmic antibodies (ANCA) in vasculitis have either cANCA or pANCA patterns as defined by immunofluorescence. The target autoantigen of…”
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Mapping Recombination Hotspots in Human Phosphoglucomutase (PGM1) by Ping Yip, Shea, Lovegrove, Jenny U., Rana, Naheed A., Hopkinson, David A., Whitehouse, David B.

“…Human phosphoglucomutase (PGM1) is a highly polymorphic protein. Three mutations and four intragenic recombination events between the three mutation sites…”
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A phylogenetic approach to the identification of phosphoglucomutase genes by Whitehouse, D B, Tomkins, J, Lovegrove, J U, Hopkinson, D A, McMillan, W O

“…The expanding molecular database provides unparalleled opportunities for characterizing genes and for studying groups of related genes. We use sequences drawn…”
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The Classical Human Phosphoglucomutase (PGM1) Isozyme Polymorphism is Generated by Intragenic Recombination by March, R. E., Putt, W., Hollyoake, M., Ives, J. H., Lovegrove, J. U., Hopkinson, D. A., Edwards, Y. H., Whitehouse, D. B.

“…The molecular basis of the classical human phosphoglucomutase 1 (PGM1) isozyme polymorphism has been established. In 1964, when this genetic polymorphism was…”
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A new alpha 1-antitrypsin mutation, Thr–Met 85, (PI Zbristol) associated with novel electrophoretic properties by LOVEGROVE, J. U., JEREMIAH, S., GILLETT, G. T., TEMPLE, I. K., POVEY, S., WHITEHOUSE, D. B.

“…A new AAT allele (PI Zbristol) has been discovered in a woman with an obstetric history of three perinatal deaths from fulminant liver disease and no living…”
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Molecular and cytological investigations of phosphoglucomutase (PGM1) in the K562 cell line by TOMKINS, J., FOX, M., LOVEGROVE, J. U., PARRINGTON, J., HOPKINSON, D. A., WHITEHOUSE, D. B.

“…Phosphoglucomutase 1 (PGM1) deficiency is a stable characteristic of the erythroleukaemic cell line, K562, whereas the activity of the isozymes of the other…”
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α1-Antitrypsin deficiency alleles and the Taq-I G→A allele in cystic fibrosis lung disease by MAHADEVA, R, WESTERBEEK, R. C, PERRY, D. J, LOVEGROVE, J. U, WHITEHOUSE, D. B, CARROLL, N. R, ROSS-RUSSELL, R. I, WEBB, A. K, BRILTON, D, LOMAS, D. A

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Prenatal diagnosis of alpha-1-antitrypsin deficiency by PCR of linked polymorphisms: a study of 17 cases by Abbott, C M, Lovegrove, J U, Whitehouse, D B, Hopkinson, D A, Povey, S

“…We describe our experiences of prenatal diagnosis of alpha-1-antitrypsin deficiency using closely linked polymorphisms detected by Southern blotting and the…”
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Phosphoglucomutase 1: Complete Human and Rabbit mRNA Sequences and Direct Mapping of this Highly Polymorphic Marker on Human Chromosome 1 by Whitehouse, D. B., Putt, W., Lovegrove, J. U., Morrison, K., Hollyoake, M., Fox, M. F., Hopkinson, D. A., Edwards, Y. H.

“…A cDNA clone encoding the mRNA for the highly polymorphic human enzyme phosphoglucomutase 1 (PGM1; EC 5.4.2.2) has been isolated and characterized. This was…”
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Genetic studies on a new deficiency gene (PIZtun) at the PI locus by Whitehouse, D B, Abbott, C M, Lovegrove, J U, McIntosh, I, McMahon, C J, Mieli-Vergani, G, Mowat, A P, Hopkinson, D A

“…During a study of the alpha 1 antitrypsin (AAT) protein and its locus (PI) by high resolution isoelectric focusing and direct molecular analysis of 106 PIZ…”
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Variation in alpha-1-antitrypsin phenotypes associated with penicillamine therapy by Whitehouse, D B, Lovegrove, J U, Hopkinson, D A

“…During a detailed study of alpha-1-antitrypsin (AAT) by isoelectric focusing, of 130 individuals of the PiZ phenotype and their families, an unusual…”
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A new alpha 1‐antitrypsin mutation, Thr–Met 85, (PI Zbristol) associated with novel electrophoretic properties by LOVEGROVE, J. U., JEREMIAH, S., GILLETT, G. T., TEMPLE, I. K., POVEY, S., WHITEHOUSE, D. B.

“…A new AAT allele (PI Zbristol) has been discovered in a woman with an obstetric history of three perinatal deaths from fulminant liver disease and no living…”
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Alpha1-antitrypsin deficiency alleles and the Taq-I G-->A allele in cystic fibrosis lung disease by Mahadeva, R, Westerbeek, RC, Perry, DJ, Lovegrove, JU, Whitehouse, DB, Carroll, NR, Ross-Russell, RI, Webb, AK, Bilton, D, Lomas, DA

“…Cystic fibrosis (CF) is characterized by progressive and ultimately fatal pulmonary disease although there are notable variations in clinical features. This…”
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'SZ like' alpha 1-antitrypsin phenotypes in PI ZZ children with liver disease by Whitehouse, D B, Lovegrove, J U, Mieli-Vergani, G, Mowat, A P, Hopkinson, D A

“…Using high resolution isoelectric focusing, alpha 1-antitrypsin phenotypes were studied in 106 individuals of the PI ZZ genotype including 71 with liver…”
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C-antineutrophil cytoplasmic antibody positivity in vasculitis patients is associated with the Z allele of alpha-1-antitrypsin, and P-antineutrophil cytoplasmic antibody positivity with the S allele by Griffith, M. E., Lovegrove, J. U., Gaskin, G., Whitehouse, D. B., Pusey, C. D.

“…Background. Antineutrophil cytoplasmic antibodies (ANCA) in vasculitis have either cANCA or pANCA patterns as defined by immunofluorescence. The target…”
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Prenatal diagnosis of alpha-1-antitrypsin deficiency by PCR of linked polymorphisms: a study of 17 cases by Abbott, C M, Lovegrove, J U, Whitehouse, D B, Hopkinson, D A, Povey, S

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Phosphoglucomutase. I: Complete human and rabbit mRNA sequences and direct mapping of this highly polymorphic marker on human chromosome 1 by WHITEHOUSE, D. B, PUTT, W, LOVEGROVE, J. U, MORRISON, K, HOLLYOAKE, M, FOX, M. F, HOPKINSON, D. A, EDWARDS, Y. H

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Genetic studies on a new deficiency gene (PI super()Z) sub(tun)) at the PI locus by Whitehouse, D B, Abbott, C M, Lovegrove, JU, McIntosh, I, McMahon, C J, Mieli-Vergani, G, Mowat, A P, Hopkinson, DA

“…During a study of the alpha sub(1) antitrypsin (AAT) protein and its locus (PI)) by high resolution isoelectric focusing and direct molecular analysis of 106…”
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