Search Results - "LOVE, Cassandra"

Viral MicroRNA Targetome of KSHV-Infected Primary Effusion Lymphoma Cell Lines by Gottwein, Eva, Corcoran, David L., Mukherjee, Neelanjan, Skalsky, Rebecca L., Hafner, Markus, Nusbaum, Jeffrey D., Shamulailatpam, Priscilla, Love, Cassandra L., Dave, Sandeep S., Tuschl, Thomas, Ohler, Uwe, Cullen, Bryan R.

“…Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The…”
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Genetic heterogeneity of diffuse large B-cell lymphoma by Zhang, Jenny, Grubor, Vladimir, Love, Cassandra L., Banerjee, Anjishnu, Richards, Kristy L., Mieczkowski, Piotr A., Dunphy, Cherie, Choi, William, Au, Wing Yan, Srivastava, Gopesh, Lugar, Patricia L, Rizzieri, David A., Lagoo, Anand S., Bernal-Mizrachi, Leon, Mann, Karen P., Flowers, Christopher, Naresh, Kikkeri, Evens, Andrew, Gordon, Leo I., Czader, Magdalena, Gill, Javed I., Hsi, Eric D., Liu, Qingquan, Fan, Alice, Walsh, Katherine, Jima, Dereje, Smith, Lisa L., Johnson, Amy J., Byrd, John C., Luftig, Micah A., Ni, Ting, Zhu, Jun, Chadburn, Amy, Levy, Shawn, Dunson, David, Dave, Sandeep S.

“…Diffuse large B-cell lymphoma (DLBCL) is the most common form of lymphoma in adults. The disease exhibits a striking heterogeneity in gene expression profiles…”
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The whole-genome landscape of Burkitt lymphoma subtypes by Panea, Razvan I., Love, Cassandra L., Shingleton, Jennifer R., Reddy, Anupama, Bailey, Jeffrey A., Moormann, Ann M., Otieno, Juliana A., Ong'echa, John Michael, Oduor, Cliff I., Schroeder, Kristin M.S., Masalu, Nestory, Chao, Nelson J., Agajanian, Megan, Major, Michael B., Fedoriw, Yuri, Richards, Kristy L., Rymkiewicz, Grzegorz, Miles, Rodney R., Alobeid, Bachir, Bhagat, Govind, Flowers, Christopher R., Ondrejka, Sarah L., Hsi, Eric D., Choi, William W.L., Au-Yeung, Rex K.H., Hartmann, Wolfgang, Lenz, Georg, Meyerson, Howard, Lin, Yen-Yu, Zhuang, Yuan, Luftig, Micah A., Waldrop, Alexander, Dave, Tushar, Thakkar, Devang, Sahay, Harshit, Li, Guojie, Palus, Brooke C., Seshadri, Vidya, Kim, So Young, Gascoyne, Randy D., Levy, Shawn, Mukhopadyay, Minerva, Dunson, David B., Dave, Sandeep S.

“…Burkitt lymphoma (BL) is an aggressive, MYC-driven lymphoma comprising 3 distinct clinical subtypes: sporadic BLs that occur worldwide, endemic BLs that occur…”
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The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells by Zhang, Jenny, Jima, Dereje, Moffitt, Andrea B., Liu, Qingquan, Czader, Magdalena, Hsi, Eric D., Fedoriw, Yuri, Dunphy, Cherie H., Richards, Kristy L., Gill, Javed I., Sun, Zhen, Love, Cassandra, Scotland, Paula, Lock, Eric, Levy, Shawn, Hsu, David S., Dunson, David, Dave, Sandeep S.

“…In this study, we define the genetic landscape of mantle cell lymphoma (MCL) through exome sequencing of 56 cases of MCL. We identified recurrent mutations in…”
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GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo by Healy, Jane A., Nugent, Adrienne, Rempel, Rachel E., Moffitt, Andrea B., Davis, Nicholas S., Jiang, Xiaoyu, Shingleton, Jennifer R., Zhang, Jenny, Love, Cassandra, Datta, Jyotishka, McKinney, Matthew E., Tzeng, Tiffany J., Wettschureck, Nina, Offermanns, Stefan, Walzer, Katelyn A., Chi, Jen-Tsan, Rasheed, Suhail A.K., Casey, Patrick J., Lossos, Izidore S., Dave, Sandeep S.

“…GNA13 is the most frequently mutated gene in germinal center (GC)-derived B-cell lymphomas, including nearly a quarter of Burkitt lymphoma and GC-derived…”
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Molecular characterization of circulating plasma cells in patients with active systemic lupus erythematosus by Lugar, Patricia L, Love, Cassandra, Grammer, Amrie C, Dave, Sandeep S, Lipsky, Peter E

“…Systemic lupus erythematosus (SLE) is a generalized autoimmune disease characterized by abnormal B cell activation and the occurrence of increased frequencies…”
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PAK1 Mediates Resistance to PI3K Inhibition in Lymphomas by WALSH, Katherine, MCKINNEY, Matthew S, LOVE, Cassandra, QINGQUAN LIU, FAN, Alice, PATEL, Amee, SMITH, Jason, BEAVEN, Anne, JIMA, Dereje D, DAVE, Sandeep S

“…The phosphoinositide 3-kinase (PI3K) pathway is known to play an active role in many malignancies. The role of PI3K inhibition in the treatment of lymphomas…”
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Id Proteins Suppress E2A-Driven Invariant Natural Killer T Cell Development prior to TCR Selection by Roy, Sumedha, Moore, Amanda J, Love, Cassandra, Reddy, Anupama, Rajagopalan, Deepthi, Dave, Sandeep S, Li, Leping, Murre, Cornelis, Zhuang, Yuan

“…A family of transcription factors known as E proteins, and their antagonists, Id proteins, regulate T cell differentiation at critical developmental…”
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The genetic landscape of immune-competent and HIV lymphoma by Zhang, Jenny, Grubor, Vladimir, Love, Cassandra L, Banerjee, Anjishnu, Richards, Kristy L, Miezcowski, Piotr, Dunphy, Cherie H, Choi, William WL, Auv, Wing-Yan, Srivastava, Gopesh, Lugar, Patricia L, Rizzieri, David A, Lagoo, Anand S, Bernal-Mizrachi, Leon, Mann, Karen P, Flowers, Christopher R, Naresh, Kikkeri N, Evens, Andrew M, Gordon, Leo I, Czader, Magdalena B, Gill, Javed I, Hsi, Eric D, Liu, Qingquan, Fan, Alice, Walsh, Katherine, Jima, Dereje D, Luftig, Micah, Ni, Ting, Zhu, Jun, Chadburn, Amy, Levy, Shawn, Dunson, David B, Dave, Sandeep S

“…Doc number: O1…”
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Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma by Reddy, Anupama, Zhang, Jenny, Davis, Nicholas S., Moffitt, Andrea B., Love, Cassandra L., Waldrop, Alexander, Leppa, Sirpa, Pasanen, Annika, Meriranta, Leo, Karjalainen-Lindsberg, Marja-Liisa, Nørgaard, Peter, Pedersen, Mette, Gang, Anne O., Høgdall, Estrid, Heavican, Tayla B., Lone, Waseem, Iqbal, Javeed, Qin, Qiu, Li, Guojie, Kim, So Young, Healy, Jane, Richards, Kristy L., Fedoriw, Yuri, Bernal-Mizrachi, Leon, Koff, Jean L., Staton, Ashley D., Flowers, Christopher R., Paltiel, Ora, Goldschmidt, Neta, Calaminici, Maria, Clear, Andrew, Gribben, John, Nguyen, Evelyn, Czader, Magdalena B., Ondrejka, Sarah L., Collie, Angela, Hsi, Eric D., Tse, Eric, Au-Yeung, Rex K.H., Kwong, Yok-Lam, Srivastava, Gopesh, Choi, William W.L., Evens, Andrew M., Pilichowska, Monika, Sengar, Manju, Reddy, Nishitha, Li, Shaoying, Chadburn, Amy, Gordon, Leo I., Jaffe, Elaine S., Levy, Shawn, Rempel, Rachel, Tzeng, Tiffany, Happ, Lanie E., Dave, Tushar, Rajagopalan, Deepthi, Datta, Jyotishka, Dunson, David B., Dave, Sandeep S.

“…Diffuse large B cell lymphoma (DLBCL) is the most common form of blood cancer and is characterized by a striking degree of genetic and clinical heterogeneity…”
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Development of a Potent DNA Damaging Agent LP-284 for Treatment of Mantle Cell Lymphoma by Zhou, Jianli, Kulkarni, Aditya, Love, Cassandra, Happ, Lanie, Sturtevant, Drew, Biyani, Neha, Peru y Colón De Portugal, Raniero L., Bhatia, Kishor, Dave, Sandeep S.

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The genetic landscape of mutations in Burkitt lymphoma by Love, Cassandra, Sun, Zhen, Jima, Dereje, Li, Guojie, Zhang, Jenny, Miles, Rodney, Richards, Kristy L, Dunphy, Cherie H, Choi, William W L, Srivastava, Gopesh, Lugar, Patricia L, Rizzieri, David A, Lagoo, Anand S, Bernal-Mizrachi, Leon, Mann, Karen P, Flowers, Christopher R, Naresh, Kikkeri N, Evens, Andrew M, Chadburn, Amy, Gordon, Leo I, Czader, Magdalena B, Gill, Javed I, Hsi, Eric D, Greenough, Adrienne, Moffitt, Andrea B, McKinney, Matthew, Banerjee, Anjishnu, Grubor, Vladimir, Levy, Shawn, Dunson, David B, Dave, Sandeep S

“…Sandeep Dave and colleagues report exome sequencing of 59 Burkitt lymphomas. They report recurrent mutations in many genes, including ID3 , MYC , GNA13 , RET ,…”
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Analytical and Clinical Validation of Duoseq, a Novel Assay for Rapid, on-Site Clinical DNA and RNA Sequencing of Hematologic Malignancies by Hsi, Eric D., Czader, Magdalena, Hill, Brian T., Thacker, Elizabeth, Wang, Lin, Giauque, Christopher, Vrydaghs, Andrea, Sperling, Matt, Bouldin, Jordan, Erno, Robert, Happ, Lanie, Parker, Clayton, Love, Cassandra L., Shingleton, Jennifer, Dave, Sandeep

“…Introduction: Next generation sequencing (NGS) has become a critical component of the workup of malignancies. NGS can provide important diagnostic information…”
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The Genetic Basis of Hepatosplenic T-cell Lymphoma by McKinney, Matthew, Moffitt, Andrea B, Gaulard, Philippe, Travert, Marion, De Leval, Laurence, Nicolae, Alina, Raffeld, Mark, Jaffe, Elaine S, Pittaluga, Stefania, Xi, Liqiang, Heavican, Tayla, Iqbal, Javeed, Belhadj, Karim, Delfau-Larue, Marie Helene, Fataccioli, Virginie, Czader, Magdalena B, Lossos, Izidore S, Chapman-Fredricks, Jennifer R, Richards, Kristy L, Fedoriw, Yuri, Ondrejka, Sarah L, Hsi, Eric D, Low, Lawrence, Weisenburger, Dennis, Chan, Wing C, Mehta-Shah, Neha, Horwitz, Steven, Bernal-Mizrachi, Leon, Flowers, Christopher R, Beaven, Anne W, Parihar, Mayur, Baseggio, Lucile, Parrens, Marie, Moreau, Anne, Sujobert, Pierre, Pilichowska, Monika, Evens, Andrew M, Chadburn, Amy, Au-Yeung, Rex K H, Srivastava, Gopesh, Choi, William W L, Goodlad, John R, Aurer, Igor, Basic-Kinda, Sandra, Gascoyne, Randy D, Davis, Nicholas S, Li, Guojie, Zhang, Jenny, Rajagopalan, Deepthi, Reddy, Anupama, Love, Cassandra, Levy, Shawn, Zhuang, Yuan, Datta, Jyotishka, Dunson, David B, Davé, Sandeep S

“…Hepatosplenic T-cell lymphoma (HSTL) is a rare and lethal lymphoma; the genetic drivers of this disease are unknown. Through whole-exome sequencing of 68…”
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Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2 by Moffitt, Andrea B, Ondrejka, Sarah L, McKinney, Matthew, Rempel, Rachel E, Goodlad, John R, Teh, Chun Huat, Leppa, Sirpa, Mannisto, Susanna, Kovanen, Panu E, Tse, Eric, Au-Yeung, Rex K H, Kwong, Yok-Lam, Srivastava, Gopesh, Iqbal, Javeed, Yu, Jiayu, Naresh, Kikkeri, Villa, Diego, Gascoyne, Randy D, Said, Jonathan, Czader, Magdalena B, Chadburn, Amy, Richards, Kristy L, Rajagopalan, Deepthi, Davis, Nicholas S, Smith, Eileen C, Palus, Brooke C, Tzeng, Tiffany J, Healy, Jane A, Lugar, Patricia L, Datta, Jyotishka, Love, Cassandra, Levy, Shawn, Dunson, David B, Zhuang, Yuan, Hsi, Eric D, Dave, Sandeep S

“…Enteropathy-associated T cell lymphoma (EATL) is a lethal, and the most common, neoplastic complication of celiac disease. Here, we defined the genetic…”
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Novel Mechanisms for Resistance to Targeted Therapy Identified through Machine Learning Approaches in 1167 RNA-Seq Drug Exposure Profiles in Lymphoma by Davis, Nicholas, McKinney, Matthew S., Reddy, Anupama, Love, Cassandra, Smith, Eileen, Happ, Lanie, Dave, Sandeep

“…Introduction: Diffuse large B cell lymphoma (DLBCL) is a clinically heterogeneous disease. While roughly half of the patients respond well to standard R-CHOP…”
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ID3 Loss In Vivo Synergizes with MYC-Driven Oncogenesis in Burkitt Lymphoma by Love, Cassandra, Remple, Rachel, Li, Guojie, Dave, Sandeep

“…Burkitt lymphoma (BL) is an aggressive cancer, characterized by the deregulation of the c-myc (MYC) gene. BL is a major model disease for molecular studies in…”
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Unraveling the Transcriptional Landscape of Nodular Lymphocyte-Predominant Hodgkin Lymphoma and T-Cell/Histiocyte Rich Large B-Cell Lymphoma: Impact of Tumor Microenvironment and Checkpoint Gene Expression by Kalashnikov, Ilja, Russell, Veronica, Kovanen, Panu, Dunkel, Johannes, Karjalainen-Lindsberg, Marja-Liisa, Pasanen, Annika, Kositsky, Rachel, Ondrejka, Sarah L., Goyal, Tanu, Hsi, Eric D., Pedersen, Mette Ølgod, Gang, Anne Ortved, Czader, Magdalena, Zhou, Jiehao, Xu, Mina, Paulson, Nathan, Koff, Jean L., Evans, Andrew G, Natkunam, Yasodha, Juskevicius, Ridas, Louissaint, Abner, Thacker, Elizabeth, Dave, Tushar, Love, Cassandra L., McCall, Chad M, Ong, Choon Kiat, Churnetski, Michael, Martin, Haley, Chapman-Fredricks, Jennifer R., Iqbal, Javeed, Chadburn, Amy, Sojitra, Payal, Behdad, Amir, Choi, William, Xu, Jie, Mason, Emily F. Ferguson, Naresh, Kikkeri N, Fedoriw, Yuri D., Soliman, Dina Sameh, Dave, Sandeep, Leppä, Sirpa

“…Introduction: Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare B-cell malignancy with a paucity of malignant cells embedded in a diverse tumor…”
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Id2 Collaborates with Id3 To Suppress Invariant NKT and Innate-like Tumors by Li, Jia, Roy, Sumedha, Kim, Young-Mi, Li, Shibo, Zhang, Baojun, Love, Cassandra, Reddy, Anupama, Rajagopalan, Deepthi, Dave, Sandeep, Diehl, Anna Mae, Zhuang, Yuan

“…Inhibitor of DNA binding (Id) proteins, including Id1-4, are transcriptional regulators involved in promoting cell proliferation and survival in various cell…”
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Extranodal Marginal Zone Lymphomas Show Recurrent Mutations in DNA Repair Genes, Cancer-Associated Proliferative Signaling and NOTCH1 Signaling Pathways, Regardless of Anatomic Site by Chapman-Fredricks, Jennifer R, Thakkar, Devang, Alderuccio, Juan Pablo, Naresh, Kikkeri N, Ondrejka, Sarah L., Hsi, Eric D., Xu, Mina L, Paulson, Nathan, Koff, Jean L., Jaye, David L, Cohen, Jonathon B., Ortved Gang, Anne, Leeman-Neill, Rebecca J, Dave, Tushar, Happ, Lanie, Love, Cassandra, Zandi, Sasan, Naushad, Hina, Mason, Emily F, Louissaint, Abner, Martin, Haley, Ong, Choon Kiat, Pillai, Raju, Pedersen, Mette Ø, Yin, C. Cameron, Choi, William, Au-Yeung, Rex Kwok Him, Karjalainen-Lindsberg, Marja-Liisa, Chadburn, Amy, Sarno, Vincent, McKinney, Matthew, Sojitra, Payal, Evans, Andrew G, Behdad, Amir, Galvez, Carlos, Cheng, Chee Leong, Czader, Magdalena, Yan, Jiong, Dave, Sandeep S., Lossos, Izidore S.

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