Search Results - "LOUNEV, VITALI"

Conversion of vascular endothelial cells into multipotent stem-like cells by Shore, Eileen M, Lounev, Vitali Y, Medici, Damian, Olsen, Bjorn R, Kalluri, Raghu, Kaplan, Frederick S

“…Under certain conditions, endothelial cells can transform into mesenchymal cell types, a process known as endothelial-to-mesenchymal transition. Damian Medici…”
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Cellular Hypoxia Promotes Heterotopic Ossification by Amplifying BMP Signaling by Wang, Haitao, Lindborg, Carter, Lounev, Vitali, Kim, Jung‐Hoon, McCarrick‐Walmsley, Ruth, Xu, Meiqi, Mangiavini, Laura, Groppe, Jay C, Shore, Eileen M, Schipani, Ernestina, Kaplan, Frederick S, Pignolo, Robert J

“…ABSTRACT Hypoxia and inflammation are implicated in the episodic induction of heterotopic endochondral ossification (HEO); however, the molecular mechanisms…”
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Identification of Progenitor Cells That Contribute to Heterotopic Skeletogenesis by Lounev, Vitali Y, Ramachandran, Rageshree, Wosczyna, Michael N, Yamamoto, Masakazu, Maidment, Andrew D.A, Shore, Eileen M, Glaser, David L, Goldhamer, David J, Kaplan, Frederick S

“…BackgroundIndividuals who have fibrodysplasia ossificans progressiva develop an ectopic skeleton because of genetic dysregulation of bone morphogenetic protein…”
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Substance P signaling mediates BMP-dependent heterotopic ossification by Kan, Lixin, Lounev, Vitali Y, Pignolo, Robert J., Duan, Lishu, Liu, Yijie, Stock, Stuart R., McGuire, Tammy L., Lu, Bao, Gerard, Norma P., Shore, Eileen M., Kaplan, Frederick S., Kessler, John A.

“…Heterotopic ossification (HO) is a disabling condition associated with neurologic injury, inflammation, and overactive bone morphogenetic protein (BMP)…”
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Fibrodysplasia ossificans progressiva: a blueprint for metamorphosis by Kaplan, Frederick S., Lounev, Vitali Y., Wang, Haitao, Pignolo, Robert J., Shore, Eileen M.

“…The most important milestone in understanding a genetic disease is the identification of the causative mutation. However, such knowledge is often insufficient…”
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Conversion of vascular endothelial cells into multipotent stem-like cells by Medici, Damian, Shore, Eileen M, Lounev, Vitali Y, Kaplan, Frederick S, Kalluri, Raghu, Olsen, Bjorn R

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Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP) by Kaplan, Frederick S., Shen, Qi, Lounev, Vitali, Seemann, Petra, Groppe, Jay, Katagiri, Takenobu, Pignolo, Robert J., Shore, Eileen M.

“…Metamorphosis, the transformation of one normal tissue or organ system into another, is a biological process rarely studied in higher vertebrates or mammals,…”
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Investigations of activated ACVR1/ALK2, a bone morphogenetic protein type I receptor, that causes fibrodysplasia ossificans progressiva by Kaplan, Frederick S, Seemann, Petra, Haupt, Julia, Xu, Meiqi, Lounev, Vitali Y, Mullins, Mary, Shore, Eileen M

“…Bone morphogenetic protein (BMP) type I receptors are serine-threonine kinase transmembrane signal transduction proteins that regulate a vast array of…”
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Matrix metalloproteinase-9 deficiency confers resilience in fibrodysplasia ossificans progressiva in a man and mice by Lounev, Vitali, Groppe, Jay C, Brewer, Niambi, Wentworth, Kelly L, Smith, Victoria, Xu, Meiqi, Schomburg, Lutz, Bhargava, Pankaj, Al Mukaddam, Mona, Hsiao, Edward C, Shore, Eileen M, Pignolo, Robert J, Kaplan, Frederick S

“…Single case studies of extraordinary disease resilience may provide therapeutic insight into conditions for which no definitive treatments exist. An otherwise…”
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Gsα Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and β-Catenin Pathways by Ramaswamy, Girish, Kim, Hyunsoo, Zhang, Deyu, Lounev, Vitali, Wu, Joy Y., Choi, Yongwon, Kaplan, Frederick S., Pignolo, Robert J., Shore, Eileen M.

“…Skeletal bone formation and maintenance requires coordinate functions of several cell types, including bone forming osteoblasts and bone resorbing osteoclasts…”
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Identification of cord blood-derived mesenchymal stem/stromal cell populations with distinct growth kinetics, differentiation potentials, and gene expression profiles by Markov, Vladimir, Kusumi, Kenro, Tadesse, Mahlet G, William, Dilusha A, Hall, Dorian M, Lounev, Vitali, Carlton, Arlene, Leonard, Jay, Cohen, Rick I, Rappaport, Eric F, Saitta, Biagio

“…Phenotypic heterogeneity has been observed among mesenchymal stem/stromal cell (MSC) populations, but specific genes associated with this variability have not…”
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Erratum: Corrigendum: Conversion of vascular endothelial cells into multipotent stem-like cells by Medici, Damian, Shore, Eileen M, Lounev, Vitali Y, Kaplan, Frederick S, Kalluri, Raghu, Olsen, Bjorn R

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Corrigendum: Conversion of vascular endothelial cells into multipotent stem-like cells by Medici, Damian, Shore, Eileen M, Lounev, Vitali Y, Kaplan, Frederick S, Kalluri, Raghu, Olsen, Bjorn R

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Correction: Corrigendum: Conversion of vascular endothelial cells into multipotent stem-like cells by Medici, Damian, Shore, Eileen M, Lounev, Vitali Y, Kaplan, Frederick S, Kalluri, Raghu, Olsen, Bjorn R

“…Nat. Med. 16, 1400–1406 (2010); published online 21 November 2010; corrected after print 7 April 2011 In the version of this article initially published, the…”
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Gs[alpha] Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and [beta]-Catenin Pathways by Ramaswamy, Girish, Kim, Hyunsoo, Zhang, Deyu, Lounev, Vitali, Wu, Joy Y, Choi, Yongwon, Kaplan, Frederick S, Pignolo, Robert J, Shore, Eileen M

“…Skeletal bone formation and maintenance requires coordinate functions of several cell types, including bone forming osteoblasts and bone resorbing osteoclasts…”
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Identification of Progenitor Cells That Contribute to Heterotopic Skeletogenesis by Lounev, Vitali Y., PhD, Shore, Eileen M., PhD, Glaser, David L., MD, Kaplan, Frederick S., MD, Maidment, Andrew D.A., PhD, Ramachandran, Rageshree, MD, PhD, Wosczyna, Michael N., BS, Yamamoto, Masakazu, PhD, Goldhamer, David J., PhD

“…Background Individuals who have fibrodysplasia ossificans progressiva develop an ectopic skeleton because of genetic dysregulation of bone morphogenetic…”
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Analysis of the CD4 Protein on Human Vaginal T Lymphocytes by FIDEL, PAUL L., WORMLEY JR, FLOYD L., CHAIBAN, JOSEPH, LOUNEV, VITALI, FIDEL, PAUL L., CHESSON, RALPH R.

“…PROBLEM: Although T lymphocytes at the human vaginal mucosa have been partially characterized, there remains a paucity of information regarding cell‐mediated…”
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