Search Results - "LOUIS, Gwendolyn"
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Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits
Published in The Journal of neuroscience (02-02-2011)“…Brown adipose tissue (BAT) thermogenesis is critical to maintain homoeothermia and is centrally controlled via sympathetic outputs. Body temperature and BAT…”
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Molecular Mapping of the Neural Pathways Linking Leptin to the Neuroendocrine Reproductive Axis
Published in Endocrinology (Philadelphia) (01-06-2011)“…Leptin communicates with the neuroendocrine reproductive axis via multiple populations of LepRb neurons that lie afferent to both Kiss1 and GnRH neurons…”
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Leptin Acts via Leptin Receptor-Expressing Lateral Hypothalamic Neurons to Modulate the Mesolimbic Dopamine System and Suppress Feeding
Published in Cell metabolism (01-08-2009)“…The lateral hypothalamic area (LHA) acts in concert with the ventral tegmental area (VTA) and other components of the mesolimbic dopamine (DA) system to…”
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Direct innervation and modulation of orexin neurons by lateral hypothalamic LepRb neurons
Published in The Journal of neuroscience (25-08-2010)“…Leptin, the adipose-derived hormonal signal of body energy stores, acts via the leptin receptor (LepRb) on neurons in multiple brain regions. We previously…”
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Effects of chronic exposure to triclosan on reproductive and thyroid endpoints in the adult Wistar female rat
Published in Journal of Toxicology and Environmental Health, Part A (01-01-2017)“…Triclosan (TCS), an antibacterial, has been shown to be an endocrine disruptor in the rat. Previously, subchronic TCS treatment to female rats was found to…”
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The effect of triclosan on the uterotrophic response to extended doses of ethinyl estradiol in the weanling rat
Published in Reproductive toxicology (Elmsford, N.Y.) (01-04-2013)“…► We characterize EE and TCS co-exposure effects on uterine growth. ► We study changes in uterine epithelial cell height and EE-regulated mRNA levels. ► TCS…”
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Direct Innervation of GnRH Neurons by Metabolic- and Sexual Odorant-Sensing Leptin Receptor Neurons in the Hypothalamic Ventral Premammillary Nucleus
Published in The Journal of neuroscience (11-03-2009)“…Leptin acts via its receptor (LepRb) on specific CNS neurons to signal the adequacy of long-term energy stores, thereby permitting the expenditure of resources…”
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Ventral tegmental area leptin receptor neurons specifically project to and regulate cocaine- and amphetamine-regulated transcript neurons of the extended central amygdala
Published in The Journal of neuroscience (21-04-2010)“…Leptin acts via its receptor (LepRb) to regulate neural circuits in concert with body energy stores. In addition to acting on a number of hypothalamic…”
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Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity
Published in PloS one (20-02-2008)“…Signal transducers and activators of transcription (STATs) are critical components of cytokine signaling pathways. STAT5A and STAT5B (STAT5), the most…”
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Tumor-Specific Urinary Matrix Metalloproteinase Fingerprinting: Identification of High Molecular Weight Urinary Matrix Metalloproteinase Species
Published in Clinical cancer research (15-10-2008)“…Purpose: We have previously reported that matrix metalloproteinases MMP-2, MMP-9, and the complex MMP-9/NGAL can be detected in urine of patients with a…”
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The Matrix Metalloproteinase-9/Neutrophil Gelatinase-Associated Lipocalin Complex Plays a Role in Breast Tumor Growth and Is Present in the Urine of Breast Cancer Patients
Published in Clinical cancer research (01-08-2005)“…Purpose: Having previously shown that the binding of neutrophil gelatinase-associated lipocalin (NGAL) to matrix metalloproteinase-9 (MMP-9) protects this…”
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Leptin Does Not Directly Affect CNS Serotonin Neurons to Influence Appetite
Published in Cell metabolism (04-05-2011)“…Serotonin (5-HT) and leptin play important roles in the modulation of energy balance. Here we investigated mechanisms by which leptin might interact with CNS…”
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Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function
Published in The Journal of clinical investigation (01-05-2007)“…The adipose-derived hormone, leptin, acts via its receptor (LRb) to convey the status of body energy stores to the brain, decreasing feeding and potentiating…”
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Urinary Metalloproteinases: Noninvasive Biomarkers for Breast Cancer Risk Assessment
Published in Cancer epidemiology, biomarkers & prevention (01-05-2008)“…Matrix metalloproteinases (MMP) and a disintegrin and metalloprotease 12 (ADAM 12) can be detected in the urine of breast cancer patients and provide…”
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A potential role for hypothalamomedullary POMC projections in leptin-induced suppression of food intake
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-03-2010)“…Melanocortin-3/4 receptor ligands administered to the caudal brain stem potently modulate food intake by changing meal size. The origin of the endogenous…”
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Matrix metalloproteinases are elevated in the urine of patients with endometriosis
Published in Fertility and sterility (01-11-2010)“…In a prospective, blinded, longitudinal study MMP-2, MMP-9, and MMP-9/neutrophil gelatinase-associated lipocalin were significantly more likely to be detected…”
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Malignant Transformation of Melanocytes to Melanoma by Constitutive Activation of Mitogen-activated Protein Kinase Kinase (MAPKK) Signaling
Published in The Journal of biological chemistry (14-03-2003)“…Malignant melanoma is the cancer with the most rapid increase in incidence in the United States. Ultraviolet light and deficiency of the p16ink4a gene are…”
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Hyperphagia and Obesity in Female Mice Lacking Tissue Inhibitor of Metalloproteinase-1
Published in Endocrinology (Philadelphia) (01-04-2009)“…Certain matrix metalloproteinases and their regulators, the tissue inhibitors of metalloproteinases (TIMPs), are involved in development and remodeling of…”
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The role of leptin in the regulation of neuroendocrine function and CNS development
Published in Reviews in endocrine & metabolic disorders (01-06-2007)“…Leptin, a hormone produced by adipocytes in proportion to fat stores, signals the sufficiency of energy reserves to the brain to control feeding and…”
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The Effects of Oral Triclosan Exposure on Reproductive Endpoints in the Female Wistar Rat
Published in Biology of reproduction (01-07-2011)Get full text
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