Search Results - "LOPEZ, Pablo H. H"

Gangliosides in cell recognition and membrane protein regulation by Lopez, Pablo HH, Schnaar, Ronald L

“…Gangliosides, sialic acid-bearing glycosphingolipids, are expressed on all vertebrate cells, and are the major glycans on nerve cells. They are anchored to the…”
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Biosynthesis of the major brain gangliosides GD1a and GT1b by Sturgill, Elizabeth R, Aoki, Kazuhiro, Lopez, Pablo H H, Colacurcio, Daniel, Vajn, Katarina, Lorenzini, Ileana, Majić, Senka, Yang, Won Ho, Heffer, Marija, Tiemeyer, Michael, Marth, Jamey D, Schnaar, Ronald L

“…Gangliosides-sialylated glycosphingolipids-are the major glycoconjugates of nerve cells. The same four structures-GM1, GD1a, GD1b and GT1b-comprise the great…”
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Molecular Identification of GD3 as a Suppressor of the Innate Immune Response in Ovarian Cancer by WEBB, Tonya J, XIANGMING LI, GIUNTOLI, Robert L, LOPEZ, Pablo H. H, HEUSER, Christoph, SCHNAAR, Ronald L, TSUJI, Moriya, KURTS, Christian, OELKE, Mathias, SCHNECK, Jonathan P

“…Tumors often display mechanisms to avoid or suppress immune recognition. One such mechanism is the shedding of gangliosides into the local tumor…”
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Blockade of Rho-associated kinase prevents inhibition of axon regeneration of peripheral nerves induced by anti-ganglioside antibodies by Berardo, Andrés, Bacaglio, Cristian R, Báez, Bárbara B, Sambuelli, Rubén, Sheikh, Kazim A, Lopez, Pablo H H

“…Anti-ganglioside antibodies are associated with delayed/poor clinical recovery in Guillain-Barrè syndrome, mostly related to halted axon regeneration…”
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Passive Immunization with Anti-Ganglioside Antibodies Directly Inhibits Axon Regeneration in an Animal Model by Lehmann, Helmar C, Lopez, Pablo H. H, Zhang, Gang, Ngyuen, Thien, Zhang, Jiangyang, Kieseier, Bernd C, Mori, Susumu, Sheikh, Kazim A

“…Recent studies have proposed that neurite outgrowth is influenced by specific nerve cell surface gangliosides, which are sialic acid-containing…”
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Gangliosides and Nogo Receptors Independently Mediate Myelin-associated Glycoprotein Inhibition of Neurite Outgrowth in Different Nerve Cells by Mehta, Niraj R., Lopez, Pablo H.H., Vyas, Alka A., Schnaar, Ronald L.

“…In the injured nervous system, myelin-associated glycoprotein (MAG) on residual myelin binds to receptors on axons, inhibits axon outgrowth, and limits…”
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Myelin-associated glycoprotein protects neurons from excitotoxicity by Lopez, Pablo H.H, Ahmad, Abdullah S, Mehta, Niraj R, Toner, Mayu, Rowland, Elizabeth A, Zhang, Jiangyang, Doré, Sylvain, Schnaar, Ronald L

“…J. Neurochem. (2011) 116, 900-908. ABSTRACT: In addition to supporting rapid nerve conduction, myelination nurtures and stabilizes axons and protects them from…”
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Gangliosides in Health and Disease by Schnaar, Ronald L, Lopez, Pablo H. H

“…Gangliosides in Health and Disease, Volume 156, presents the latest information on Gangliosides, a class of glycolipids that are found on all vertebrate cell…”
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Neurite atrophy and apoptosis mediated by PERK signaling after accumulation of GM2-ganglioside by Virgolini, María José, Feliziani, Constanza, Cambiasso, María Julia, Lopez, Pablo H., Bollo, Mariana

“…GM2-gangliosidosis, a subgroup of lysosomal storage disorders, is caused by deficiency of hexosaminidase activity, and comprises the closely related Tay-Sachs…”
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Tumor necrosis factor α receptor 1A transduces the inhibitory effect on axon regeneration triggered by IgG anti-ganglioside GD1a antibodies by Báez, Bárbara B., Bacaglio, Cristian R., Prendergast, Jillian M., Rozés-Salvador, Victoria, Sheikh, Kazim A., Bianchet, Mario, Farah, Mohamed H., Schnaar, Ronald L., Bisbal, Mariano, Lopez, Pablo H.H.

“…Anti-ganglioside antibodies (anti-Gg Abs) have been linked to delayed/poor clinical recovery in both axonal and demyelinating forms of Guillain-Barrè Syndrome…”
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Myelin-associated glycoprotein and its axonal receptors by Schnaar, Ronald L., Lopez, Pablo H.H.

“…Myelin‐associated glycoprotein (MAG) is expressed on the innermost myelin membrane wrap, directly apposed to the axon surface. Although it is not required for…”
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Evidence for spontaneous regulation of the humoral IgM anti‐GM1 autoimmune response by IgG antibodies in multifocal motor neuropathy patients by Di Egidio, Marianna, Bacaglio, Cristian R., Arrejoría, Rocio, Villa, Andrés M., Nores, Gustavo A., Lopez, Pablo H. H.

“…Abstract Background and Aims Multifocal motor neuropathy (MMN) is a peripheral nerve disorder characterized by slow progressive distal asymmetric weakness with…”
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Gangliosides in Axon Stability and Regeneration by Lopez, Pablo H H, Báez, Bárbara Beatriz

“…Gangliosides are a family of sialic acid-containing glycosphingolipids highly expressed in the nervous system of vertebrates. Over the last 25years, research…”
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Host membrane glycosphingolipids and lipid microdomains facilitate Histoplasma capsulatum internalisation by macrophages by Guimarães, Allan J., Cerqueira, Mariana Duarte, Zamith‐Miranda, Daniel, Lopez, Pablo H., Rodrigues, Marcio L., Pontes, Bruno, Viana, Nathan B., DeLeon‐Rodriguez, Carlos M., Rossi, Diego Conrado Pereira, Casadevall, Arturo, Gomes, Andre M.O., Martinez, Luis R., Schnaar, Ronald L., Nosanchuk, Joshua D., Nimrichter, Leonardo

“…Recognition and internalisation of intracellular pathogens by host cells is a multifactorial process, involving both stable and transient interactions. The…”
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Anti-glycan antibodies halt axon regeneration in a model of Guillain Barrè Syndrome axonal neuropathy by inducing microtubule disorganization via RhoA–ROCK-dependent inactivation of CRMP-2 by Rozés Salvador, Victoria, Heredia, Florencia, Berardo, Andrés, Palandri, Anabela, Wojnacki, Jose, Vivinetto, Ana L., Sheikh, Kazim A., Caceres, Alfredo, Lopez, Pablo H.H.

“…Several reports have linked the presence of high titers of anti-Gg Abs with delayed recovery/poor prognosis in GBS. In most cases, failure to recover is…”
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Anti-ganglioside antibody-mediated activation of RhoA induces inhibition of neurite outgrowth by Zhang, Gang, Lehmann, Helmar C, Manoharan, Sowmia, Hashmi, Mohammedali, Shim, Sangwoo, Ming, Guo-Li, Schnaar, Ronald L, Lopez, Pablo H, Bogdanova, Nataliia, Sheikh, Kazim A

“…Anti-ganglioside antibodies (Abs) are strongly associated with axonal forms of Guillain Barré syndrome (GBS). Some studies indicate that these Abs, including…”
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Passive transfer of IgG anti-GM1 antibodies impairs peripheral nerve repair by Lopez, Pablo H, Zhang, Gang, Zhang, Jiangyang, Lehmann, Helmar C, Griffin, John W, Schnaar, Ronald L, Sheikh, Kazim A

“…Anti-GM1 antibodies are present in some patients with autoimmune neurological disorders. These antibodies are most frequently associated with acute immune…”
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Structural requirements of anti-GD1a antibodies determine their target specificity by Lopez, Pablo H. H., Zhang, Gang, Bianchet, Mario A., Schnaar, Ronald L., Sheikh, Kazim A.

“…The acute motor axonal neuropathy (AMAN) variant of Guillain–Barré syndrome (GBS) is associated with anti-GD1a and anti-GM1 IgG antibodies. The basis of…”
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Determination of glycolipid-protein interaction specificity by Lopez, Pablo H H, Schnaar, Ronald L

“…Glycolipids are found on all eukaryotic cells. Their expression varies among tissues, with the highest density found in the brain, where glycolipids are the…”
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Preface and Ganglioside Nomenclature by Schnaar, Ronald L, Lopez, Pablo H H

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