Search Results - "LOOAREESUWAN, S"

Effects of artesunate-mefloquine combination on incidence of Plasmodium falciparum malaria and mefloquine resistance in western Thailand: a prospective study by Nosten, F, van Vugt, M, Price, R, Luxemburger, C, Thway, KL, Brockman, A, McGready, R, ter Kuile, F, Looareesuwan, S, White, NJ

“…Worsening drug resistance in Plasmodium falciparum malaria is a major threat to health in tropical countries. We did a prospective study of malaria incidence…”
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Pharmacokinetics and Pharmacodynamics of Lumefantrine (Benflumetol) in Acute Falciparum Malaria by EZZET, F, VAN VUGT, M, NOSTEN, F, LOOAREESUWAN, S, WHITE, N. J

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Fake antimalarials in Southeast Asia are a major impediment to malaria control: multinational cross‐sectional survey on the prevalence of fake antimalarials by Dondorp, A. M., Newton, P. N., Mayxay, M., Van Damme, W., Smithuis, F. M., Yeung, S., Petit, A., Lynam, A. J., Johnson, A., Hien, T. T., McGready, R., Farrar, J. J., Looareesuwan, S., Day, N. P. J., Green, M. D., White, N. J.

“…Summary Objective  To assess the prevalence of counterfeit antimalarial drugs in Southeast (SE) Asia. Design  Cross‐sectional survey. Setting  Pharmacies and…”
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Effects of Plasmodium vivax malaria in pregnancy by Nosten, F, McGready, R, Simpson, JA, Thwai, KL, Balkan, S, Cho, Thein, Hkirijaroen, L, Looareesuwan, S, White, NJ

“…Plasmodium vivax is more common than P falciparum as a cause of malaria in many parts of the tropics outside Africa. P falciparum infection has harmful effects…”
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Src-family kinase–dependent disruption of endothelial barrier function by Plasmodium falciparum merozoite proteins by Gillrie, Mark R., Krishnegowda, Gowdahalli, Lee, Kristine, Buret, Andre G., Robbins, Stephen M., Looareesuwan, S., Gowda, D. Channe, Ho, May

“…Pulmonary complication in severe Plasmodium falciparum malaria is manifested as a prolonged impairment of gas transfer or the more severe acute respiratory…”
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New Fixed-Dose Artesunate-Mefloquine Formulation against Multidrug-Resistant Plasmodium falciparum in Adults: a Comparative Phase IIb Safety and Pharmacokinetic Study with Standard-Dose Nonfixed Artesunate plus Mefloquine by Krudsood, S, Looareesuwan, S, Tangpukdee, N, Wilairatana, P, Phumratanaprapin, W, Leowattana, W, Chalermrut, K, Ramanathan, S, Navaratnam, V, Olliaro, P, Vaillant, M, Kiechel, J R, Taylor, W R J

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A Randomized, Controlled Study of a Simple, Once-Daily Regimen of Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated, Multidrug-Resistant Falciparum Malaria by Ashley, Elizabeth A., McGready, Rose, Hutagalung, Robert, Phaiphun, Lucy, Slight, Thra, Proux, Stephane, Thwai, Kyaw Lay, Barends, Marion, Looareesuwan, Sornchai, White, Nicholas J., Nosten, François

“…Background. Dihydroartemisinin-piperaquine (DP) is a fixed-combination antimalarial drug increasingly deployed in Southeast Asia. The current regimen involves…”
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Averting a malaria disaster by White, NJ, Nosten, F, Looareesuwan, S, Watkins, WM, Marsh, K, Snow, RW, Kokwaro, G, Ouma, J, Hien, TT, Molyneux, ME, Taylor, TE, Newbold, CI, Ruebush, TK, Danis, M, Greenwood, BM, Anderson, RM, Olliaro, P

“…As treatments loose their effectiveness, morbidity and mortality from malaria will inevitably continue to rise. The rationale for combining drugs with…”
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Pharmacokinetics of dihydroartemisinin following oral artesunate treatment of pregnant women with acute uncomplicated falciparum malaria by MCGREADY, R, STEPNIEWSKA, K, WARD, S. A, CHO, T, GILVERAY, G, LOOAREESUWAN, S, WHITE, N. J, NOSTEN, F

“…To determine the pharmacokinetic properties of dihydroartemisinin (DHA) following oral artesunate treatment in women with recrudescent multi-drug resistant…”
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Pregnancy and use of oral contraceptives reduces the biotransformation of proguanil to cycloguanil by MCGREADY, R, STEPNIEWSKA, K, NOSTEN, F, SEATON, E, CHO, T, CHO, D, GINSBERG, A, EDSTEIN, M. D, ASHLEY, E, LOOAREESUWAN, S, WHITE, N. J

“…To determine the effects of late pregnancy and also oestrogen supplementation on the CYP2C19-mediated biotransformation of proguanil (PG) to its active antifol…”
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Safety of the insect repellent N,N-diethyl-M-toluamide (DEET) in pregnancy by McGready, R, Hamilton, K A, Simpson, J A, Cho, T, Luxemburger, C, Edwards, R, Looareesuwan, S, White, N J, Nosten, F, Lindsay, S W

“…The safety of daily application of N, N-diethyl-m-toluamide (DEET) (1.7 g of DEET/day) in the second and third trimesters of pregnancy was assessed as part of…”
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The pharmacokinetics of atovaquone and proguanil in pregnant women with acute falciparum malaria by MCGREADY, R, STEPNIEWSKA, K, EDSTEIN, M. D, CHO, T, GILVERAY, G, LOOAREESUWAN, S, WHITE, N. J, NOSTEN, F

“…To determine the pharmacokinetic properties of atovaquone, proguanil, and the triazine metabolite cycloguanil in women with recrudescent multi-drug resistant…”
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Association of genetic mutations in Plasmodium vivax dhfr with resistance to sulfadoxine-pyrimethamine: Geographical and clinical correlates by IMWONG, Mallika, PUKRITTAKAYAMEE, Sasithon, LOOAREESUWAN, Sornchai, PASVOL, Geoffrey, POIRRIEZ, Jean, WHITE, Nicholas J, SNOUNOU, Georges

“…Mutations in the Plasmodium falciparum gene (dhfr) encoding dihydrofolate reductase are associated with resistance to antifols. Plasmodium vivax, the more…”
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INTESTINAL HELMINTH INFECTIONS ARE ASSOCIATED WITH INCREASED INCIDENCE OF PLASMODIUM FALCIPARUM MALARIA IN THAILAND by Nacher, M, Singhasivanon, P, Yimsamran, S, Manibunyong, W, Thanyavanich, N, Wuthisen, P, Looareesuwan, S

“…In a prospective study of the total population of 5 hamlets on the western border of Thailand, all subjects were screened for helminth infections; during the…”
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Randomized Trial of 3-Dose Regimens of Tafenoquine (WR238605) versus Low-Dose Primaquine for Preventing Plasmodium vivax Malaria Relapse by Walsh, Douglas S., Wilairatana, Polrat, Tang, Douglas B., Heppner, D. Gray, Brewer, Thomas G., Krudsood, Srivicha, Silachamroon, Udomsak, Phumratanaprapin, Weerapong, Siriyanonda, Duangsuda, Looareesuwan, Sornchai

“…Background. Tafenoquine is an 8-aminoquinoline developed as a more effective replacement for primaquine. In a previous dose-ranging study in Thailand, 3…”
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Adverse Effect of Rifampin on Quinine Efficacy in Uncomplicated Falciparum Malaria by PUKRITTAYAKAMEE, S, PRAKONGPAN, S, WANWIMOLRUK, S, CLEMENS, R, LOOAREESUWAN, S, WHITE, N. J

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Quinine Pharmacokinetic-Pharmacodynamic Relationships in Uncomplicated Falciparum Malaria by PUKRITTAYAKAMEE, S, WANWIMOLRUK, S, STEPNIEWSKA, K, JANTRA, A, HUYAKORN, S, LOOAREESUWAN, S, WHITE, N. J

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Effect of artesunate and mefloquine in combination on the Fridericia corrected QT intervals in Plasmodium falciparum infected adults from Thailand by Krudsood, S., Looareesuwan, S., Wilairatama, P., Leowattana, W., Tangpukdee, N., Chalermrut, K., Ramanathan, S., Navaratnam, V., Olliaro, P., Vaillant, M., Kiechel, J. R., Taylor, W. R. J.

“…Summary Objective  To ascertain whether mefloquine (MQ) produces electrocardiogram (ECG) changes that could be a risk for Torsades de Pointe (TdP), a…”
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Plasmodium falciparum antimalarial drug susceptibility on the north-western border of Thailand during five years of extensive use of artesunate-mefloquine by Brockman, A., Price, R.N., van Vugt, M., Heppner, D.G., Walsh, D., Sookto, P., Wimonwattrawatee, T., Looareesuwan, S., White, N.J., Nosten, F.

“…Following a marked decline in the efficacy in vivo of mefloquine between 1990 and 1994, a combination of artesunate (4 mg/kg/d for 3 d) and mefloquine (25…”
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Efficacy of six doses of artemether-lumefantrine (benflumetol) in multidrug-resistant Plasmodium falciparum malaria by Vugt, M V, Wilairatana, P, Gemperli, B, Gathmann, I, Phaipun, L, Brockman, A, Luxemburger, C, White, N J, Nosten, F, Looareesuwan, S

“…The new oral fixed combination artemether-lumefantrine (CGP 56697) has proved to be an effective and well-tolerated treatment of multi-drug resistant…”
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