Search Results - "LONN, E."

Diabetes clinical trials: helped or hindered by the current shift in regulatory requirements? by ZANNAD, Faiez, STOUGH, Wendy Gattis, ABADIE, Eric, ALONSO-GARCIA, Angeles, PITT, Bertram, POCOCK, Stuart J, SLEIGHT, Peter, CUSHMAN, William C, CLELAND, John G. F, MCMURRAY, John J. V, LONN, Eva, GELLER, Nancy L, WEDEL, Hans

“…Glycaemic control is an inadequate surrogate marker of cardiovascular event reduction in patients with type 2 diabetes. Clinical trials to date have been…”
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Early Initiation of Sacubitril/Valsartan in Patients With Acute Heart Failure and Renal Dysfunction: An Analysis of the TRANSITION Study by STRABURZYNSKA-MIGAJ, EWA, SENNI, M., WACHTER, R., FONSECA, C., WITTE, K.K., MUELLER, C., LONN, E., BUTYLIN, D., NOE, A., SCHWENDE, H., LAWRENCE, D., SURYAWANSHI, B., PASCUAL-FIGAL, D.

“…•Treatment of patients with decompensated HFrEF and RD is challenging.•Effect of RD on initiation of sacubitril/valsartan was studied.•Most HF patients with RD…”
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The relationship between dysglycaemia and cardiovascular and renal risk in diabetic and non-diabetic participants in the HOPE study : a prospective epidemiological analysis by GERSTEIN, H. C, POGUE, J, MANN, J. F. E, LONN, E, DAGENAIS, G. R, MCQUEEN, M, YUSUF, S

“…Emerging data suggest that different indices of glycaemia are risk factors for clinical events. The aim of this analysis was to investigate the relationship…”
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Common carotid intima-media thickness does not add to Framingham risk score in individuals with diabetes mellitus: the USE-IMT initiative by den Ruijter, H. M., Peters, S. A. E., Groenewegen, K. A., Anderson, T. J., Britton, A. R., Dekker, J. M., Engström, G., Eijkemans, M. J., Evans, G. W., de Graaf, J., Grobbee, D. E., Hedblad, B., Hofman, A., Holewijn, S., Ikeda, A., Kavousi, M., Kitagawa, K., Kitamura, A., Koffijberg, H., Ikram, M. A., Lonn, E. M., Lorenz, M. W., Mathiesen, E. B., Nijpels, G., Okazaki, S., O’Leary, D. H., Polak, J. F., Price, J. F., Robertson, C., Rembold, C. M., Rosvall, M., Rundek, T., Salonen, J. T., Sitzer, M., Stehouwer, C. D. A., Witteman, J. C., Moons, K. G., Bots, M. L.

“…Aims/hypothesis The aim of this work was to investigate whether measurement of the mean common carotid intima-media thickness (CIMT) improves cardiovascular…”
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Cardiovascular risk factors and non-invasive assessment of subclinical atherosclerosis in youth by Morrison, K.M, Dyal, L, Conner, W, Helden, E, Newkirk, L, Yusuf, S, Lonn, E

“…Abstract Our understanding of the natural history of atherosclerosis in childhood and its response to cardiovascular (CV) risk factor reduction have been…”
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Effects of Ramipril and Rosiglitazone on Cardiovascular and Renal Outcomes in People With Impaired Glucose Tolerance or Impaired Fasting Glucose : Results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial by Dagenais, G R, Gerstein, H C, Holman, R, Budaj, A, Escalante, A, Hedner, T, Keltai, M, Lonn, E, McFarlane, S, McQueen, M, Teo, K, Sheridan, P, Bosch, J, Pogue, J, Yusuf, S

“…Impaired glucose tolerance (IGT) and/or impaired fasting glucose (IFG) are risk factors for diabetes, cardiovascular disease (CVD), and kidney disease. We…”
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Resting heart rate is associated with renal disease outcomes in patients with vascular disease: results of the ONTARGET and TRANSCEND studies by Böhm, M., Schumacher, H., Schmieder, R. E., Mann, J. F. E., Teo, K., Lonn, E., Sleight, P., Mancia, G., Linz, D., Mahfoud, F., Ukena, C., Sliwa, K., Bakris, G., Yusuf, S.

“…Background Resting heart rate (RHR) is associated with cardiovascular disease outcomes in high‐risk patients. It is not known whether RHR is predictive of…”
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Vitamin D and progression of carotid intima‐media thickness in HIV‐positive Canadians by Huff, H, Merchant, AT, Lonn, E, Pullenayegum, E, Smaill, F, Smieja, M

“…Objectives Based on a growing body of evidence implicating low vitamin D status in the development of cardiovascular disease (CVD), we hypothesized that in…”
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Low resting heart rates are associated with new‐onset atrial fibrillation in patients with vascular disease: results of the ONTARGET/TRANSCEND studies by Böhm, M., Schumacher, H., Linz, D., Reil, J.‐C., Ukena, C., Lonn, E., Teo, K., Sliwa, K., Schmieder, R. E., Sleight, P., Yusuf, S.

“…Background Elevated systolic blood pressure (SBP) and high resting heart rate (HR) are associated with cardiovascular end‐points. Although the association…”
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Usefulness of N-Terminal Pro–Brain Natriuretic Peptide and Brain Natriuretic Peptide to Predict Cardiovascular Outcomes in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction by Grewal, Jasmine, MD, McKelvie, Robert S., PhD, Persson, Hans, PhD, Tait, Peter, Msc, Carlsson, Jonas, Msc, Swedberg, Karl, PhD, Ostergren, Jan, PhD, Lonn, Eva, MD

“…More than 40% of patients hospitalized with heart failure have preserved left ventricular ejection fraction (HF-PLVEF) and are at high risk for cardiovascular…”
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Increased cardiovascular risk after pre-eclampsia in women with dysglycaemia by McDonald, S. D., Yusuf, S., Walsh, M. W., Lonn, E., Teo, K., Anand, S. S., Pogue, J., Islam, S., Devereaux, P. J., Gerstein, H. C.

“…Aims Compared with women with uncomplicated pregnancies, women with a history of pre‐eclampsia have two to five times the risk of cardiovascular disease. It is…”
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Risk of premature stroke in recent immigrants (PRESARIO): Population-based matched cohort study by SAPOSNIK, G, REDELMEIER, D. A, LU, H, LONN, E, FULLER-THOMSON, E, RAY, J. G

“…New immigrants to North America, most of whom are under age 50 years, exhibit fewer risk factors for cardiovascular disease than their native-born…”
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Modifying the natural history of atherosclerosis: the SECURE trial by Lonn, E

“…Experimental and epidemiological evidence suggests that activation of the reninangiotensin-aldosterone system and oxidative modification of low density…”
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A comparison of the assessment and management of cardiometabolic risk in patients with and without type 2 diabetes mellitus in Canadian primary care by Teoh, H., Després, J.-P., Dufour, R., Fitchett, D. H., Goldin, L., Goodman, S. G., Harris, S. B., Langer, A., Lau, D. C. W., Lonn, E. M., Mancini, G. B. J., McFarlane, P. A., Poirier, P., Rabasa-Lhoret, R., Tan, M. K., Leiter, L. A.

“…Aim To investigate the cardiometabolic risk (CMR) assessment and management patterns for individuals with and without type 2 diabetes mellitus (T2DM) in…”
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Effects of ramipril and vitamin E on atherosclerosis : The Study to Evaluate Carotid Ultrasound changes in patients treated with ramipril and vitamin E (SECURE) by LONN, Eva M, YUSUF, Salim, DZAVIK, Vladimir, DORIS, C. Ian, QILONG YI, SMITH, Sandra, MOORE-COX, Anne, BOSCH, Jackie, RILEY, Ward A, TEO, Koon K

“…Activation of the renin-angiotensin-aldosterone system and oxidative modification of LDL cholesterol play important roles in atherosclerosis. The Study to…”
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Effect of long-term ACE-inhibitor therapy in elderly vascular disease patients by Gianni, Monica, Bosch, Jackie, Pogue, Janice, Probstfield, Jeffrey, Dagenais, Gilles, Yusuf, Salim, Lonn, Eva

“…Aims Cardiovascular (CV) disease is the leading cause of death in the elderly. The use of ACE-inhibitors in elderly patients with chronic stable vascular…”
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Automated oscillometric blood pressure versus auscultatory blood pressure as a predictor of carotid intima-medial thickness in male firefighters by CAMPBELL, N. R. C, MCKAY, D. W, CONRADSON, H, LONN, E, TITLE, L. M, ANDERSON, T

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Myocardial infarction Associated with Recency of Immigration to Ontario by Saposnik, G., Redelmeier, D.A., Lu, H., Fuller-Thomson, E., Lonn, E., Ray, J.G.

“…Background: New immigrants to North America exhibit lower rates of obesity and hypertension than their native-born counterparts. Whether this is reflected by a…”
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Venous thromboembolism in association with features of the metabolic syndrome by Ray, J.G., Lonn, E., Yi, Q., Rathe, A., Sheridan, P., Kearon, C.

“…Background: Central obesity, diabetes mellitus, dyslipidaemia and chronic hypertension—features of the metabolic syndrome—have been individually associated…”
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Cross-sectional evaluation of brachial artery flow-mediated vasodilation and C-reactive protein in healthy individuals by Verma, Subodh, Wang, Chao-Hung, Lonn, Eva, Charbonneau, Francois, Buithieu, Jean, Title, Lawrence M., Fung, Marinda, Edworthy, Steve, Robertson, Annette C., Anderson, Todd J.

“…Aims The present study was designed to (a) examine the interrelationship between endothelial function and CRP in healthy individuals and (b) evaluate the…”
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