Search Results - "LONGONI, Nicole"

miR-21: an oncomir on strike in prostate cancer by Folini, Marco, Gandellini, Paolo, Longoni, Nicole, Profumo, Valentina, Callari, Maurizio, Pennati, Marzia, Colecchia, Maurizio, Supino, Rosanna, Veneroni, Silvia, Salvioni, Roberto, Valdagni, Riccardo, Daidone, Maria Grazia, Zaffaroni, Nadia

“…Aberrant expression of microRNAs, small non-coding RNA molecules that post-transcriptionally repress gene expression, seems to be causatively linked to the…”
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miR-205 Exerts Tumor-Suppressive Functions in Human Prostate through Down-regulation of Protein Kinase Cε by GANDELLINI, Paolo, FOLINI, Marco, VALDAGN, Riccardo, GRAZIA DAIDONE, Maria, ZAFFARONI, Nadia, LONGONI, Nicole, PENNATI, Marzia, BIND, Mara, COLECCHIA, Maurizio, SALVIONI, Roberto, SUPINO, Rosanna, MORETTI, Roberta, LIMONTA, Patrizia

“…Abstract Limited information is available concerning the expression and role of microRNAs in prostate cancer. In this study, we investigated the involvement of…”
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ESE3/EHF Controls Epithelial Cell Differentiation and Its Loss Leads to Prostate Tumors with Mesenchymal and Stem-like Features by ALBINO, Domenico, LONGONI, Nicole, CHIORINO, Giovanna, CATAPANO, Carlo V, CARBONE, Giuseppina M, CURTI, Laura, MELLO-GRAND, Maurizia, PINTON, Sandra, CIVENNI, Gianluca, THALMANN, George, D'AMBROSIO, Gioacchino, SARTI, Manuela, SESSA, Fausto

“…Cancer stem cells (CSC) play a significant role in tumor progression, disease recurrence, and treatment failure. Here, we show that the endogenously expressed…”
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EC-70124, a Novel Glycosylated Indolocarbazole Multikinase Inhibitor, Reverts Tumorigenic and Stem Cell Properties in Prostate Cancer by Inhibiting STAT3 and NF-κB by Civenni, Gianluca, Longoni, Nicole, Costales, Paula, Dallavalle, Cecilia, García Inclán, Cristina, Albino, Domenico, Nuñez, Luz Elena, Morís, Francisco, Carbone, Giuseppina M, Catapano, Carlo V

“…Cancer stem cells (CSC) contribute to disease progression and treatment failure in prostate cancer because of their intrinsic resistance to current therapies…”
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ETS Transcription Factor ESE1/ELF3 Orchestrates a Positive Feedback Loop That Constitutively Activates NF-κB and Drives Prostate Cancer Progression by LONGONI, Nicole, SARTI, Manuela, SESSA, Fausto, GARCIA-ESCUDERO, Ramon, THALMANN, George N, CHIORINO, Giovanna, CATAPANO, Carlo V, CARBONE, Giuseppina M, ALBINO, Domenico, CIVENNI, Gianluca, MALEK, Anastasia, ORTELLI, Erica, PINTON, Sandra, MELLO-GRAND, Maurizia, OSTANO, Paola, D'AMBROSIO, Gioacchino

“…Chromosomal translocations leading to deregulated expression of ETS transcription factors are frequent in prostate tumors. Here, we report a novel mechanism…”
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Abstract B25: The ETS transcription factor ESE1 promotes activation of the NFKB pathway in prostate tumors by Longoni, Nicole, Mello-Grand, Maurizia, Sarti, Manuela, Pinton, Sandra, Dallavalle, Cecilia, Chiorino, Giovanna, Catapano, Carlo V., Carbone, Giuseppina M.

“…Abstract ETS transcription factors are important elements in the pathogenesis of prostate cancer. Here, we report that the ETS factor ESE1, which is expressed…”
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Abstract 3118: ESE1/ELF3 and constitutive activation of NF-kB in human prostate cancer: prognostic relevance and rationale for context-dependent therapeutic strategies by Longoni, Nicole, Albino, Domenico, Civenni, Gianluca, Pinton, Sandra, Mello-Grand, Maurizia, Ostano, Paola, D’ Ambrosio, Gioacchino, Sessa, Fausto, Thalmann, George N., Sarti, Manuela, Garcia-Escudero, Ramon, Morris, Francisco, Chiorino, Giovanna, Catapano, Carlo V., Carbone, Giuseppina M.

“…Abstract Activation of inflammatory circuits occurs frequently in human cancers. Here, we show that ESE1/ELF3 exerts oncogenic functions and is an important…”
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Abstract C21: LincRNA expression data analysis identifies prostate tumor subtypes with distinct biological processes by Mello-Grand, Maurizia, Singh, Vijay K., Ghimenti, Chiara, Scatolini, Maria, Longoni, Nicole, Curti, Laura, Zitella, Andrea, Gontero, Paolo, Catapano, Carlo V., Carbone, Giuseppina M., Chiorino, Giovanna

“…Abstract Prostate cancer (PCa) shows tremendous heterogeneity which makes it difficult to identify patients with an increased risk of disease recurrence. A…”
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Abstract 5019: Loss of the ETS transcription factor ESE3 induces epithelial-mesenchimal transition and generates cells with stem cell-like properties by Albino, Domenico, Longoni, Nicole, Ortelli, Erica, Kunderfranco, Paolo, Malek, Anastasia, Catapano, Carlo V., Carbone, Giuseppina MR

“…Abstract ETS transcription factors have emerged as important elements in the pathogenesis of prostate cancer. Most ETS factors promote cell proliferation,…”
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Abstract B24: Loss of expression of the endogenous ETS factor ESE3/EHF is associated with a distinct tumor subtype with stem-like and basal cell features by Mello-Grand, Maurizia, Sarti, Manuela, D'Ambrosio, Gioacchino, Sessa, Fausto, Thalmann, George, Chiorino, Giovanna, Catapano, Carlo V., Carbone, Giuseppina MR, Albino, Domenico, Singh, Vijay Kumar, Civenni, Gianluca, Longoni, Nicole, Ghimenti, Chiara, Ostano, Paola, Pinton, Sandra

“…Abstract Gene fusions leading to ectopic expression of ETS transcription factors are frequent in prostate tumors. However, the impact of endogenously expressed…”
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Abstract 4965: The epithelial-specific ETS transcription factor ESE1 links inflammation with prostate cancer transformation and progression by Longoni, Nicole, Ortelli, Erica, Kunderfranco, Paolo, Genini, Davide, Grand, Maurizia Mello, Chiorino, Giovanna, Malek, Anastasia, Catapano, Carlo V., Carbone, Giuseppina M.

“…Abstract Altered expression of ETS transcription factors by chromosomal translocation is a frequent event in prostate cancers. However, deregulated expression…”
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miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon by Gandellini, Paolo, Folini, Marco, Longoni, Nicole, Pennati, Marzia, Binda, Mara, Colecchia, Maurizio, Salvioni, Roberto, Supino, Rosanna, Moretti, Roberta, Limonta, Patrizia, Valdagni, Riccardo, Daidone, Maria Grazia, Zaffaroni, Nadia

“…Limited information is available concerning the expression and role of microRNAs in prostate cancer. In this study, we investigated the involvement of miR-205…”
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