Search Results - "LONGONI, Biancamaria"
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Atypical Antipsychotics and Metabolic Syndrome: From Molecular Mechanisms to Clinical Differences
Published in Pharmaceuticals (Basel, Switzerland) (08-03-2021)“…Atypical antipsychotics (AAPs) are commonly prescribed medications to treat schizophrenia, bipolar disorders and other psychotic disorders. However, they might…”
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Polyunsaturated Lipids in the Light-Exposed and Prooxidant Retinal Environment
Published in Antioxidants (01-03-2023)“…The retina is an oxidative stress-prone tissue due to high content of polyunsaturated lipids, exposure to visible light stimuli in the 400-480 nm range, and…”
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3
Therapeutic Drug Monitoring in Psychiatry: Enhancing Treatment Precision and Patient Outcomes
Published in Pharmaceuticals (Basel, Switzerland) (01-05-2024)“…Psychiatric disorders often require pharmacological interventions to alleviate symptoms and improve quality of life. However, achieving an optimal therapeutic…”
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4
Retinoid Synthesis Regulation by Retinal Cells in Health and Disease
Published in Cells (Basel, Switzerland) (18-05-2024)“…Vision starts in retinal photoreceptors when specialized proteins (opsins) sense photons via their covalently bonded vitamin A derivative 11cis retinaldehyde…”
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A 5-Year Study of Lithium and Valproic Acid Drug Monitoring in Patients with Bipolar Disorders in an Italian Clinical Center
Published in Pharmaceuticals (Basel, Switzerland) (17-01-2022)“…Therapeutic drug monitoring (TDM) is an effective tool used to improve the pharmacological treatment in clinical practice, especially to detect subtherapeutic…”
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Mesenchymal Stem Cell in Pancreatic Islet Transplantation
Published in Biomedicines (11-05-2023)“…Pancreatic islet transplantation is a therapeutic option for achieving physiologic regulation of plasma glucose in Type 1 diabetic patients. At the same time,…”
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Is Adult Hippocampal Neurogenesis Really Relevant for the Treatment of Psychiatric Disorders?
Published in Current neuropharmacology (01-01-2021)“…Adult neurogenesis consists in the generation of newborn neurons from neural stem cells taking place in the adult brain. In mammals, this process is limited to…”
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Electrophysiological Profile Remodeling via Selective Suppression of Voltage-Gated Currents by CLN1 /PPT1 Overexpression in Human Neuronal-Like Cells
Published in Frontiers in cellular neuroscience (16-12-2020)“…CLN1 disease (OMIM #256730) is an inherited neurological disorder of early childhood with epileptic seizures and premature death. It is associated with…”
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Co-transplantation of endothelial progenitor cells and pancreatic islets to induce long-lasting normoglycemia in streptozotocin-treated diabetic rats
Published in PloS one (01-04-2014)“…Graft vascularization is a crucial step to obtain stable normoglycemia in pancreatic islet transplantation. Endothelial progenitor cells (EPCs) contribute to…”
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Stem cell-based immunomodulation in type 1 diabetes: beyond the regenerative approach
Published in Current pharmaceutical design (01-10-2011)“…Type 1 diabetes (T1D) is an autoimmune disease, leading to pancreatic β-cell destruction and loss of glycaemic control. Administration of exogenous insulin to…”
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Cigarette smoke extract induces oxidative stress and apoptosis in human lung fibroblasts
Published in American journal of physiology. Lung cellular and molecular physiology (01-06-2003)“…Cigarette smoke is a mixture of chemicals having direct and/or indirect toxic effects on different lung cells. We investigated the effect of cigarette smoke on…”
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12
Magnetic carbon nanotubes: a new tool for shepherding mesenchymal stem cells by magnetic fields
Published in Nanomedicine (London, England) (01-01-2011)“…We investigated the interaction between magnetic carbon nanotubes (CNTs) and mesenchymal stem cells (MSCs), and their ability to guide these intravenously…”
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13
Oxidative Stress and Inflammatory Reaction Modulation by White Wine
Published in Annals of the New York Academy of Sciences (01-05-2002)“…: Wine and olive oil, essential components of the Mediterranean diet, are considered important factors for a healthy life style. Tyrosol (T) and caffeic acid…”
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14
Functional characterisation and subcellular localisation of HCN1 channels in rabbit retinal rod photoreceptors
Published in The Journal of physiology (01-07-2002)“…Gating of voltage-dependent conductances in retinal photoreceptors is the first step of a process leading to the enhancement of the temporal performance of the…”
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Properties and functional roles of hyperpolarization-gated currents in guinea-pig retinal rods
Published in The Journal of physiology (15-03-1999)“…The inward rectification induced by membrane hyperpolarization was studied in adult guinea-pig rods by the perforated-patch-clamp technique. CsCl blocked the…”
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Effects of melatonin on lipid peroxidation induced by oxygen radicals
Published in Life sciences (1973) (1998)“…We here report the activity of the neurohormone melatonin (MLT) as a scavenger of free radicals in two different experimental models: (a) linoleic acid…”
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A New Threat to Dopamine Neurons: The Downside of Artificial Light
Published in Neuroscience (15-04-2020)“…[Display omitted] •Artificial light could indirectly damage dopamine neurons blunting the circadian rhythms of melatonin secretion.•Artificial light could…”
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Pharmacological Strategies for Bipolar Disorders in Acute Phases and Chronic Management with a Special Focus on Lithium, Valproic Acid, and Atypical Antipsychotics
Published in Current neuropharmacology (01-01-2023)“…Bipolar disorders (BDs) are a heterogeneous group of severe affective disorders generally described by the alternation of (hypo)manic, depressive, and mixed…”
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19
Quantum dots labelling allows detection of the homing of mesenchymal stem cells administered as immunomodulatory therapy in an experimental model of pancreatic islets transplantation
Published in Journal of anatomy (01-03-2017)“…Cell transplantation is considered a promising therapeutic approach in several pathologies but still needs innovative and non‐invasive imaging technologies to…”
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Pharmacological Strategies for Bipolar Disorders in Acute Phases and Chronic Management with a Special Focus on Lithium, Valproic Acid, and Atypical Antipsychotics
Published in Current neuropharmacology (2022)“…Bipolar disorders (BDs) are a heterogeneous group of severe affective disorders generally described by the alternation of (hypo)manic, depressive, and mixed…”
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