Search Results - "LONGHI, Silvia A"

Combination of ultra-rapid DNA purification (PURE) and loop-mediated isothermal amplification (LAMP) for rapid detection of Trypanosoma cruzi DNA in dried blood spots by Longhi, Silvia A, García Casares, Lady J, Muñoz-Calderón, Arturo A, Alonso-Padilla, Julio, Schijman, Alejandro G

“…Chagas disease or American trypanosomiasis, a neglected tropical disease, is a persistent Public Health problem in Latin America and other, non-endemic,…”
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Trypanosoma cruzi loop-mediated isothermal amplification (Trypanosoma cruzi Loopamp) kit for detection of congenital, acute and Chagas disease reactivation by Besuschio, Susana A, Picado, Albert, Muñoz-Calderón, Arturo, Wehrendt, Diana P, Fernández, Marisa, Benatar, Alejandro, Diaz-Bello, Zoraida, Irurtia, Cecilia, Cruz, Israel, Ndung'u, Joseph M, Cafferata, María L, Montenegro, Graciela, Sosa Estani, Sergio, Lucero, Raúl H, Alarcón de Noya, Belkisyole, Longhi, Silvia A, Schijman, Alejandro G

“…A Trypanosoma cruzi Loopamp kit was recently developed as a ready-to-use diagnostic method requiring minimal laboratory facilities. We evaluated its diagnostic…”
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Novel 3D human trophoblast culture to explore T. cruzi infection in the placenta by Apodaca, Sofia, Di Salvatore, Marco, Muñoz-Calderón, Arturo, Curto, María de Los Ángeles, Longhi, Silvia A, Schijman, Alejandro G

“…Human trophoblastic cell lines, such as BeWo, are commonly used in 2D models to study placental infections. However, these models do not accurately represent…”
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Methodological approach to the ex vivo expansion and detection of T. cruzi-specific T cells from chronic Chagas disease patients by Acevedo, Gonzalo R, Longhi, Silvia A, Bunying, Alcinette, Sabri, Nazila, Atienza, Augusto, Zago, María P, Santos, Radleigh, Judkowski, Valeria A, Pinilla, Clemencia, Gómez, Karina A

“…The discovery of T cell epitopes is essential not only for gaining knowledge about host response to infectious disease but also for the development of…”
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Correction: Methodological approach to the ex vivo expansion and detection of T. cruzi-specific T cells from chronic Chagas disease patients by Acevedo, Gonzalo R, Longhi, Silvia A, Bunying, Alcinette, Sabri, Nazila, Atienza, Augusto, Zago, María P, Santos, Radleigh, Judkowski, Valeria A, Pinilla, Clemencia, Gómez, Karina A

“…[This corrects the article DOI: 10.1371/journal.pone.0178380.]…”
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Loop-Mediated Isothermal Amplification of Trypanosoma cruzi DNA for Point-of-Care Follow-Up of Anti-Parasitic Treatment of Chagas Disease by Muñoz-Calderón, Arturo A, Besuschio, Susana A, Wong, Season, Fernández, Marisa, García Cáceres, Lady J, Giorgio, Patricia, Barcan, Laura A, Markham, Cole, Liu, Yanwen E, de Noya, Belkisyole Alarcón, Longhi, Silvia A, Schijman, Alejandro G

“…A loop-mediated isothermal amplification assay was evaluated as a surrogate marker of treatment failure in Chagas disease (CD). A convenience series of 18…”
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Cytokine production but lack of proliferation in peripheral blood mononuclear cells from chronic Chagas' disease cardiomyopathy patients in response to T. cruzi ribosomal P proteins by Longhi, Silvia A, Atienza, Augusto, Perez Prados, Graciela, Buying, Alcinette, Balouz, Virginia, Buscaglia, Carlos A, Santos, Radleigh, Tasso, Laura M, Bonato, Ricardo, Chiale, Pablo, Pinilla, Clemencia, Judkowski, Valeria A, Gómez, Karina A

“…Trypanosoma cruzi ribosomal P proteins, P2β and P0, induce high levels of antibodies in patients with chronic Chagas' disease Cardiomyopathy (CCC). It is well…”
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Epsin N-Terminal Homology Domains Perform an Essential Function Regulating Cdc42 through Binding Cdc42 GTPase-Activating Proteins by Aguilar, Rubén C., Longhi, Silvia A., Shaw, Jonathan D., Yeh, Lan-Yu, Kim, Sean, Schön, Arne, Freire, Ernesto, Hsu, Ariel, McCormick, William K., Watson, Hadiya A., Wendland, Beverly

“…Epsins are endocytic proteins with a structured epsin N-terminal homology (ENTH) domain that binds phosphoinositides and a poorly structured C-terminal region…”
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Serological based monitoring of a cohort of patients with chronic Chagas disease treated with benznidazole in a highly endemic area of northern Argentina by Niborski, Leticia L, Grippo, Vanina, Lafón, Sonia O, Levitus, Gabriela, García-Bournissen, Facundo, Ramirez, Juan C, Burgos, Juan M, Bisio, Margarita, Juiz, Natalia A, Ayala, Vilma, Coppede, María, Herrera, Verónica, López, Crescencia, Contreras, Ana, Gómez, Karina A, Elean, Juan C, Mujica, Hugo D, Schijman, Alejandro G, Levin, Mariano J, Longhi, Silvia A

“…This study aimed to evaluate well-documented diagnostic antigens, named B13, 1F8 and JL7 recombinant proteins, as potential markers of seroconversion in…”
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Selective blockade of trypanosomatid protein synthesis by a recombinant antibody anti-Trypanosoma cruzi P2β protein by Ayub, Maximiliano Juri, Nyambega, Benson, Simonetti, Leandro, Duffy, Tomas, Longhi, Silvia A, Gómez, Karina A, Hoebeke, Johan, Levin, Mariano J, Smulski, Cristian R

“…The ribosomal P proteins are located on the stalk of the ribosomal large subunit and play a critical role during the elongation step of protein synthesis. The…”
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Antibodies against the Trypanosoma cruzi ribosomal P proteins induce apoptosis in HL-1 cardiac cells by Levy, Gabriela V., Tasso, Laura M., Longhi, Silvia A., Rivello, Hernán García, Kytö, Ville, Saukko, Pekka, Levin, Mariano J., Gómez, Karina A.

“…[Display omitted] ► The monoclonal antibody against the C-terminal end of the Trypanosoma cruzi ribosomal P2 protein (R13 peptide), called mAb 17.2, and its…”
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Interaction map of the Trypanosoma cruzi ribosomal P protein complex (stalk) and the elongation factor 2 by Smulski, Cristian R., Longhi, Silvia A., Ayub, Maximiliano Juri, Edreira, Martin M., Simonetti, Leandro, Gómez, Karina A., Basile, Joaquín N., Chaloin, Olivier, Hoebeke, Johan, Levin, Mariano J.

“…The large subunit of the eukaryotic ribosome possesses a long and protruding stalk formed by the ribosomal P proteins. This structure is involved in the…”
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Enzymatic synthesis of bile acid derivatives and biological evaluation against Trypanosoma cruzi by García Liñares, Guadalupe, Antonela Zígolo, M., Simonetti, Leandro, Longhi, Silvia A., Baldessari, Alicia

“…[Display omitted] Enzyme catalysis was applied to synthesize derivatives of three bile acids and their biological activity was evaluated as growth inhibitors…”
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Alterations in Placental Gene Expression of Pregnant Women with Chronic Chagas Disease by Juiz, Natalia A., Torrejón, Irma, Burgos, Marianela, Torres, Ana M.F., Duffy, Tomás, Cayo, Nelly M., Tabasco, Anahí, Salvo, Miriam, Longhi, Silvia A., Schijman, Alejandro G.

“…Trypanosoma cruzi infection in women of reproductive age is associated with congenital transmission and adverse pregnancy outcomes. The placenta is a key…”
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Human Polymorphisms in Placentally Expressed Genes and Their Association With Susceptibility to Congenital Trypanosoma cruzi Infection by Juiz, Natalia A., Cayo, Nelly M., Burgos, Marianela, Salvo, Miriam E., Nasser, Julio R., Búa, Jacqueline, Longhi, Silvia A., Schijman, Alejandro G.

“…Background. It is currently unclear why only a proportion of children born to Trypanosoma cruzi–infected mothers acquire the infection. We have examined the…”
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Short Report: Evaluation of In-House ELISA Using Trypanosoma cruzi Lysate and Recombinant Antigens for Diagnosis of Chagas Disease and Discrimination of Its Clinical Forms by LONGHI, Silvia A, BRANDARIZ, Silvia B, LAFON, Sonia O, NIBORSKI, Leticia L, LUQUETTI, Alejandro O, SCHIJMAN, Alejandro G, LEVIN, Mariano J, GOMEZ, Karina A

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Evaluation of in-house ELISA using Trypanosoma cruzi lysate and recombinant antigens for diagnosis of Chagas disease and discrimination of its clinical forms by Longhi, Silvia A, Brandariz, Silvia B, Lafon, Sonia O, Niborski, Leticia L, Luquetti, Alejandro O, Schijman, Alejandro G, Levin, Mariano J, Gómez, Karina A

“…The aim of this work was to investigate the potential usefulness of Trypanosoma cruzi lysate, recombinant protein JL7, and peptides P013, R13, JL18, JL19, and…”
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yeast endocytic protein Epsin 2 functions in a cell-division signaling pathway by Mukherjee, Debarati, Coon, Brian G, Edwards, Daniel F. III, Hanna, Claudia B, Longhi, Silvia A, McCaffery, J. Michael, Wendland, Beverly, Retegui, Lilia A, Bi, Erfei, Aguilar, R. Claudio

“…The epsins are a family of adaptors involved in recruiting other endocytic proteins, binding of ubiquitylated cargo and induction of membrane curvature. These…”
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Interaction map of the Trypanosoma cruzi ribosomal P protein complex (stalk) and the elongation factor 2 by Smulski, Cristian R, Longhi, Silvia A, Ayub, Maximiliano Juri, Edreira, Martin M, Simonetti, Leandro, Gómez, Karina A, Basile, Joaquín N, Chaloin, Olivier, Hoebeke, Johan, Levin, Mariano J

“…The large subunit of the eukaryotic ribosome possesses a long and protruding stalk formed by the ribosomal P proteins. This structure is involved in the…”
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Peltophorum dubium and soybean Kunitz-type trypsin inhibitors induce human Jurkat cell apoptosis by Troncoso, María F., Biron, Verónica A., Longhi, Silvia A., Retegui, Lilia A., Wolfenstein-Todel, Carlota

“…Plants constitute an important source of compounds which can induce apoptosis in a variety of cells. Previously, we reported the isolation of a trypsin…”
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