Search Results - "LONGHI, Renato"

Dichotomy of short and long thymic stromal lymphopoietin isoforms in inflammatory disorders of the bowel and skin by Fornasa, Giulia, PhD, Tsilingiri, Katerina, PhD, Caprioli, Flavio, MD, PhD, Botti, Fiorenzo, MD, Mapelli, Marina, PhD, Meller, Stephan, MD, Kislat, Andreas, MSc, Homey, Bernhard, MD, Di Sabatino, Antonio, MD, Sonzogni, Angelica, MD, Viale, Giuseppe, MD, PhD, Diaferia, Giuseppe, PhD, Gori, Alessandro, PhD, Longhi, Renato, PhD, Penna, Giuseppe, MSc, Rescigno, Maria, PhD

“…Background Thymic stromal lymphopoietin (TSLP) is a cytokine with pleiotropic functions in the immune system. It has been associated with allergic reactions in…”
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Host plant peptides elicit a transcriptional response to control the Sinorhizobium meliloti cell cycle during symbiosis by Penterman, Jon, Abo, Ryan P., De Nisco, Nicole J., Arnold, Markus F. F., Longhi, Renato, Zanda, Matteo, Walker, Graham C.

“…The α-proteobacterium Sinorhizobium meliloti establishes a chronic intracellular infection during the symbiosis with its legume hosts. Within specialized host…”
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Protection of Sinorhizobium against host cysteine-rich antimicrobial peptides is critical for symbiosis by Haag, Andreas F, Baloban, Mikhail, Sani, Monica, Kerscher, Bernhard, Pierre, Olivier, Farkas, Attila, Longhi, Renato, Boncompagni, Eric, Hérouart, Didier, Dall'angelo, Sergio, Kondorosi, Eva, Zanda, Matteo, Mergaert, Peter, Ferguson, Gail P

“…Sinorhizobium meliloti differentiates into persisting, nitrogen-fixing bacteroids within root nodules of the legume Medicago truncatula. Nodule-specific…”
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Spontaneous Formation of L-Isoaspartate and Gain of Function in Fibronectin by Curnis, Flavio, Longhi, Renato, Crippa, Luca, Cattaneo, Angela, Dondossola, Eleonora, Bachi, Angela, Corti, Angelo

“…Isoaspartate formation in extracellular matrix proteins, by aspartate isomerization or asparagine deamidation, is generally viewed as a degradation reaction…”
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The P2Y-like receptor GPR17 as a sensor of damage and a new potential target in spinal cord injury by Ceruti, Stefania, Villa, Giovanni, Genovese, Tiziana, Mazzon, Emanuela, Longhi, Renato, Rosa, Patrizia, Bramanti, Placido, Cuzzocrea, Salvatore, Abbracchio, Maria P.

“…Upon central nervous system injury, the extracellular concentrations of nucleotides and cysteinyl-leukotrienes, two unrelated families of endogenous signalling…”
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Targeting liposomal chemotherapy via both tumor cell-specific and tumor vasculature- specific ligands potentiates therapeutic efficacy by PASTORINO, Fabio, BRIGNOLE, Chiara, RIBATTI, Domenico, CORTI, Angelo, ALLEN, Theresa M, PONZONI, Mirco, DI PAOLO, Daniela, NICO, Bice, PEZZOLO, Annalisa, MARIMPIETRI, Danilo, PAGNAN, Gabriella, PICCARDI, Federica, CILLI, Michele, LONGHI, Renato

“…Neuroblastoma, the most common solid tumor of infancy derived from the sympathetic nervous system, continues to present a formidable clinical challenge…”
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Kinetics of Contact Formation and End-to-End Distance Distributions of Swollen Disordered Peptides by Soranno, Andrea, Longhi, Renato, Bellini, Tommaso, Buscaglia, Marco

“…Unstructured polypeptide chains are subject to various degrees of swelling or compaction depending on the combination of solvent condition and amino acid…”
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Characterization of the cell penetrating properties of a human salivary proline-rich peptide by Radicioni, Giorgia, Stringaro, Annarita, Molinari, Agnese, Nocca, Giuseppina, Longhi, Renato, Pirolli, Davide, Scarano, Emanuele, Iavarone, Federica, Manconi, Barbara, Cabras, Tiziana, Messana, Irene, Castagnola, Massimo, Vitali, Alberto

“…Saliva contains hundreds of small proline-rich peptides most of which derive from the post-translational and post-secretory processing of the acidic and basic…”
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Critical Role of Flanking Residues in NGR-to-isoDGR Transition and CD13/Integrin Receptor Switching by Curnis, Flavio, Cattaneo, Angela, Longhi, Renato, Sacchi, Angelina, Gasparri, Anna Maria, Pastorino, Fabio, Di Matteo, Paola, Traversari, Catia, Bachi, Angela, Ponzoni, Mirco, Rizzardi, Gian-Paolo, Corti, Angelo

“…Various NGR-containing peptides have been exploited for targeted delivery of drugs to CD13-positive tumor neovasculature. Recent studies have shown that…”
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In vivo study of the role of α6‐containing nicotinic acetylcholine receptor in retinal function using subtype‐specific RDP‐MII(E11R) toxin by Barloscio, Davide, Cerri, Elisa, Domenici, Luciano, Longhi, Renato, Dallanoce, Clelia, Moretti, Milena, Vilella, Antonietta, Zoli, Michele, Gotti, Cecilia, Origlia, Nicola

“…Although a6‐contaning (a6*) nicotinic acetylcholine receptors (nAChRs) are densely expressed in the visual system, their role is not well known. We have…”
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The expression of GHS-R in primary neurons is dependent upon maturation stage and regional localization by Lattuada, Donatella, Crotta, Katia, Tonna, Noemi, Casnici, Claudia, Benfante, Roberta, Fornasari, Diego, Bianco, Fabio, Longhi, Renato, Marelli, Ornella

“…Ghrelin is a hormone with a crucial role in the regulation of appetite, regulation of inflammation, glucose metabolism and cell proliferation. In the brain…”
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Antagonistic Effect of a Salivary Proline-Rich Peptide on the Cytosolic Ca2+ Mobilization Induced by Progesterone in Oral Squamous Cancer Cells by Palmerini, Carlo Alberto, Mazzoni, Michela, Radicioni, Giorgia, Marzano, Valeria, Granieri, Letizia, Iavarone, Federica, Longhi, Renato, Messana, Irene, Cabras, Tiziana, Sanna, Maria Teresa, Castagnola, Massimo, Vitali, Alberto

“…A salivary proline-rich peptide of 1932 Da showed a dose-dependent antagonistic effect on the cytosolic Ca2+ mobilization induced by progesterone in a tongue…”
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Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node by Brioschi, Chiara, Micheloni, Stefano, Tellez, James O, Pisoni, Giuliano, Longhi, Renato, Moroni, Paolo, Billeter, Rudi, Barbuti, Andrea, Dobrzynski, Halina, Boyett, Mark R, DiFrancesco, Dario, Baruscotti, Mirko

“…Abstract Several studies of the pacemaker mechanisms in mammalian cells, most of which were carried out in cells isolated from the rabbit sinoatrial node…”
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Cancer immunotherapy based on killing of Salmonella-infected tumor cells by AVOGADRI, Francesca, MARTINOLI, Chiara, PETROVSKA, Liljana, CHIODONI, Claudia, TRANSIDICO, Pietro, BRONTE, Vincenzo, LONGHI, Renato, COLOMBO, Mario P, DOUGAN, Gordon, RESCIGNO, Maria

“…A major obstacle for the development of effective immunotherapy is the ability of tumors to escape the immune system. The possibility to kill tumor cells…”
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Isoaspartate-Glycine-Arginine : A New Tumor Vasculature-Targeting Motif by CURNIS, Flavio, SACCHI, Angelina, GASPARRI, Anna, LONGHI, Renato, BACHI, Angela, DOGLIONI, Claudio, BORDIGNON, Claudio, TRAVERSARI, Catia, RIZZARDI, Gian-Paolo, CORTI, Angelo

“…Asparagine deamidation in peptides or in fibronectin fragments containing the asparagine-glycine-arginine sequence generates isoaspartate-glycine-arginine…”
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Structural studies and SH3 domain binding properties of a human antiviral salivary proline-rich peptide by Righino, Benedetta, Pirolli, Davide, Radicioni, Giorgia, Marzano, Valeria, Longhi, Renato, Arcovito, Alessandro, Sanna, Maria Teresa, De Rosa, Maria Cristina, Paoluzi, Serena, Cesareni, Gianni, Messana, Irene, Castagnola, Massimo, Vitali, Alberto

“…Human saliva contains hundreds of small proline‐rich peptides originated by the proteolytic cleavage of the salivary basic Proline‐Rich Proteins. Nevertheless…”
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Enhanced Antitumor Efficacy of Clinical-Grade Vasculature-Targeted Liposomal Doxorubicin by PASTORINO, Fabio, DI PAOLO, Daniela, MARIMPIETRI, Danilo, PAGNAN, Gabriella, CILLI, Michele, LEPEKHIN, Eugene A, GARDE, Seema V, LONGHI, Renato, CORTI, Angelo, ALLEN, Theresa M, WU, Jinzi J, PONZONI, Mirco, PICCARDI, Federica, NICO, Beatrice, RIBATTI, Domenico, DAGA, Antonio, BAIO, Gabriella, NEUMAIER, Carlo E, BRIGNOLE, Chiara, LOI, Monica

“…Purpose: In vivo evaluation of good manufacturing practice-grade targeted liposomal doxorubicin (TVT-DOX), bound to a CD13 isoform expressed on the vasculature…”
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Structure-Activity Relationships of Linear and Cyclic Peptides Containing the NGR Tumor-homing Motif by Colombo, Giorgio, Curnis, Flavio, De Mori, Giacomo M.S., Gasparri, Anna, Longoni, Cristina, Sacchi, Angelina, Longhi, Renato, Corti, Angelo

“…Cyclic and linear peptides containing the Asn-Gly-Arg (NGR) motif have proven useful for delivering various anti-tumor compounds and viral particles to tumor…”
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Non-redundant role for IL-12 and IL-27 in modulating Th2 polarization of carcinoembryonic antigen specific CD4 T cells from pancreatic cancer patients by Tassi, Elena, Braga, Marco, Longhi, Renato, Gavazzi, Francesca, Parmiani, Giorgio, Di Carlo, Valerio, Protti, Maria Pia

“…Pancreatic cancer is a very aggressive disease with dismal prognosis; peculiar is the tumor microenvironment characterized by an extensive fibrotic stroma,…”
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Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies by immunoprecipitation by Gotti, Cecilia, Moretti, Milena, Bohr, Iwo, Ziabreva, Iryna, Vailati, Silvia, Longhi, Renato, Riganti, Loredana, Gaimarri, Annalisa, McKeith, Ian G., Perry, Robert H., Aarsland, Dag, Larsen, Jan Petter, Sher, Emanuele, Beattie, Ruth, Clementi, Francesco, Court, Jennifer A.

“…Antibodies raised against human α2-6 and β2-4 nicotinic receptor subunits were utilized to fractionate 3H-epibatidine binding in human temporal cortex and…”
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