Search Results - "LONDON, L"

Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis by Xiang, Yan, Stine, Zachary E, Xia, Jinsong, Lu, Yunqi, O'Connor, Roddy S, Altman, Brian J, Hsieh, Annie L, Gouw, Arvin M, Thomas, Ajit G, Gao, Ping, Sun, Linchong, Song, Libing, Yan, Benedict, Slusher, Barbara S, Zhuo, Jingli, Ooi, London L, Lee, Caroline G L, Mancuso, Anthony, McCallion, Andrew S, Le, Anne, Milone, Michael C, Rayport, Stephen, Felsher, Dean W, Dang, Chi V

“…Glutaminase (GLS), which converts glutamine to glutamate, plays a key role in cancer cell metabolism, growth, and proliferation. GLS is being explored as a…”
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Microvascular Invasion Is a Better Predictor of Tumor Recurrence and Overall Survival Following Surgical Resection for Hepatocellular Carcinoma Compared to the Milan Criteria by LIM, Kheng-Choon, CHOW, Pierce Kah-Hoe, ALLEN, John C, CHIA, Ghim-Song, LIM, Miaoshan, CHEOW, Peng-Chung, CHUNG, Alexander Y. F, OOI, London L. P, TAN, Say-Beng

“…To compare microvascular invasion (McVI) with parameters defined by the Milan criteria in predicting tumor recurrence and overall survival (OS) in patients…”
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Changing trends and outcomes associated with the adoption of minimally invasive hepatectomy: a contemporary single-institution experience with 400 consecutive resections by Goh, Brian K. P., Lee, Ser-Yee, Teo, Jin-Yao, Kam, Juinn-Huar, Jeyaraj, Prema-Raj, Cheow, Peng-Chung, Chow, Pierce K. H., Ooi, London L. P. J., Chung, Alexander Y. F., Chan, Chung-Yip

“…Background Several studies published mainly from pioneers and early adopters have documented the evolution of minimally invasive hepatectomy (MIH). However,…”
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Profiling MicroRNA Expression in Hepatocellular Carcinoma Reveals MicroRNA-224 Up-regulation and Apoptosis Inhibitor-5 as a MicroRNA-224-specific Target by Wang, Yu, Lee, Alvin T.C., Ma, Joel Z.I., Wang, Jingbo, Ren, Jianwei, Yang, Yuchen, Tantoso, Erwin, Li, Kuo-Bin, Ooi, London L. P. J, Tan, Patrick, Lee, Caroline G.L.

“…Like other cancers, aberrant gene regulation features significantly in hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) were recently found to regulate gene…”
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Impact of liver cirrhosis on the difficulty of minimally-invasive liver resections: a 1:1 coarsened exact-matched controlled study by Goh, Brian K. P., Syn, Nicholas, Lee, Ser-Yee, Koh, Ye-Xin, Teo, Jin-Yao, Kam, Juinn-Huar, Cheow, Peng-Chung, Jeyaraj, Prema-Raj, Chow, Pierce K., Ooi, London L., Chung, Alexander Y., Chan, Chung-Yip

“…Introduction The impact of liver cirrhosis on the difficulty of minimal invasive liver resection (MILR) remains controversial and current difficulty scoring…”
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Perioperative Outcomes of Laparoscopic Repeat Liver Resection for Recurrent HCC: Comparison with Open Repeat Liver Resection for Recurrent HCC and Laparoscopic Resection for Primary HCC by Goh, Brian K. P., Syn, Nicholas, Teo, Jin-Yao, Guo, Yu-Xin, Lee, Ser-Yee, Cheow, Peng-Chung, Chow, Pierce K. H., Ooi, London L. P. J., Chung, Alexander Y. F., Chan, Chung-Yip

“…Background This study aims to determine the safety and efficacy of laparoscopic repeat liver resection (LRLR) for recurrent hepatocellular carcinoma (rHCC)…”
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MicroRNA-224 targets SMAD family member 4 to promote cell proliferation and negatively influence patient survival by Wang, Yu, Ren, Jianwei, Gao, Yun, Ma, Joel Z I, Toh, Han Chong, Chow, Pierce, Chung, Alexander Y F, Ooi, London L P J, Lee, Caroline G L

“…MicroRNA-224 (miR-224) is frequently over-expressed in liver and colorectal cancers. We and others have previously described the role of miR-224…”
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Comprehensive analysis of transcriptome profiles in hepatocellular carcinoma by Jin, Yu, Lee, Wai Yeow, Toh, Soo Ting, Tennakoon, Chandana, Toh, Han Chong, Chow, Pierce Kah-Hoe, Chung, Alexander Y-F, Chong, Samuel S, Ooi, London L-P-J, Sung, Wing-Kin, Lee, Caroline G-L

“…Hepatocellular carcinoma is the second most deadly cancer with late presentation and limited treatment options, highlighting an urgent need to better…”
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Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3 by Wang, Yu, Lu, Yiwei, Toh, Soo Ting, Sung, Wing-Kin, Tan, Patrick, Chow, Pierce, Chung, Alexander Y.F, Jooi, London L.P, Lee, Caroline G.L

“…Background & Aims The pleiotropic hepatitis B virus (HBV) x protein (HBx), associated with hepatocellular carcinoma (HCC), has been implicated in the…”
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MicroRNA‐224 is up‐regulated in hepatocellular carcinoma through epigenetic mechanisms by Wang, Yu, Toh, Han Chong, Chow, Pierce, Chung, Alexander Y. F., Meyers, David J., Cole, Philip A., Ooi, London L. P. J., Lee, Caroline G. L.

“…ABSTRACT MicroRNA‐224 (miR‐224) is one of the most commonly up‐regulated microRNAs in hepatocellular carcinoma (HCC), which affects crucial cellular processes…”
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Importance of tumor size as a prognostic factor after partial liver resection for solitary hepatocellular carcinoma: Implications on the current AJCC staging system by Goh, Brian K. P., Teo, Jin-Yao, Chan, Chung-Yip, Lee, Ser-Yee, Jeyaraj, Premaraj, Cheow, Peng-Chung, Chow, Pierce K. H., Ooi, London L. P. J., Chung, Alexander Y. F.

“…Background Presently, the impact of tumors size as a prognostic factor after curative liver resection (LR) for solitary hepatocellular carcinoma (HCC) remains…”
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Comparison between short and long‐term outcomes after minimally invasive versus open primary liver resections for hepatocellular carcinoma: A 1:1 matched analysis by Goh, Brian K. P., Syn, Nicholas, Koh, Ye‐Xin, Teo, Jin‐Yao, Cheow, Peng‐Chung, Jeyaraj, Prema R., Chow, Pierce K. H., Ooi, London L. P. J., Chung, Alexander Y. F., Chan, Chung‐Yip

“…Background This study aims to compare the short‐ and long‐term outcomes of patients undergoing minimally invasive liver resection (MILR) versus open liver…”
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Preoperative Predictors of Early Recurrence After Liver Resection for Multifocal Hepatocellular Carcinoma by Guo, Yuxin, Linn, Yun Le, Koh, Ye Xin, Tan, Ek Khoon, Teo, Jin Yao, Cheow, Peng Chung, Jeyaraj, Prema Raj, Chow, Pierce K. H., Ooi, London L. P. J., Chung, Alexander Y. F., Chan, Chung Yip, Goh, Brian K. P.

“…Background Liver transplantation remains the optimal treatment for multifocal hepatocellular carcinoma (HCC). However, due to resource constrains, other…”
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Isolation and quarantine in South Africa during COVID-19: Draconian measures or proportional response? by Moodley, K, Obasa, A E, London, L

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Factors associated with and outcomes of open conversion after laparoscopic minor hepatectomy: initial experience at a single institution by Goh, Brian K. P., Chan, Chung-Yip, Wong, Jen-San, Lee, Ser-Yee, Lee, Victor T. W., Cheow, Peng-Chung, Chow, Pierce K. H., Ooi, London L. P. J., Chung, Alexander Y. F.

“…Background Laparoscopic liver resection has been increasingly adopted worldwide as a result of the rapid advancement in surgical techniques and equipment. This…”
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Impact of spontaneous rupture on the survival outcomes after liver resection for hepatocellular carcinoma: A propensity matched analysis comparing ruptured versus non-ruptured tumors by Chua, Darren W., Koh, Ye-Xin, Allen, John C., Chan, Chung-Yip, Lee, Ser-Yee, Cheow, Peng-Chung, Jeyaraj, Premaraj, Teo, Jin-Yao, Chow, Pierce K., Chung, Alexander Y., Ooi, London L., Goh, Brian K.P.

“…Spontaneous rupture of HCC (srHCC) is a life-threatening sequela of HCC characterized by a high mortality. Liver resection (LR) is the ideal therapeutic…”
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Shortfall in stroke care : a study of ischaemic stroke care practices in a South African metropole by Mandizvidza, V, London, L, Bryer, A

“…Background. In recent years there have been significant advances in the management of stroke. In particular, reperfusion therapies have been shown to confer…”
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Methylation profiles reveal distinct subgroup of hepatocellular carcinoma patients with poor prognosis by Mah, Way-Champ, Thurnherr, Thomas, Chow, Pierce K H, Chung, Alexander Y F, Ooi, London L P J, Toh, Han Chong, Teh, Bin Tean, Saunthararajah, Yogen, Lee, Caroline G L

“…Hepatocellular Carcinoma (HCC) is one of the leading causes of cancer-associated mortality worldwide. However, the role of epigenetic changes such as aberrant…”
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Erratum to “Book Review: The right to health – Theory and practice, Gillian Blackman, Studentlitteratur (2012), ISBN 978-9144067803 [Public Health 127 (2013): 297]” by London, L

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Critical appraisal of the impact of individual surgeon experience on the outcomes of laparoscopic liver resection in the modern era: collective experience of multiple surgeons at a single institution with 324 consecutive cases by Goh, Brian K. P., Teo, Jin-Yao, Lee, Ser-Yee, Kam, Juinn-Huar, Cheow, Peng-Chung, Jeyaraj, Premaraj, Chow, Pierce K. H., Ooi, London L. P. J., Chung, Alexander Y. F., Chan, Chung-Yip

“…Background Most studies analyzing the learning experience of laparoscopic liver resection (LLR) focused on the experience of one or two expert pioneering…”
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