Search Results - "LONDON, Barry"

JAHA : The End of the Beginning by London, Barry

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Reviewing Peer Review by London, Barry

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Diversity, Equity, and Inclusiveness in Medicine and Cardiology by London, Barry

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Mouse models of long QT syndrome by Salama, Guy, London, Barry

“…Congenital long QT syndrome is a rare inherited condition characterized by prolongation of action potential duration (APD) in cardiac myocytes, prolongation of…”
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Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery by Aragam, Krishna G, Chaffin, Mark, Levinson, Rebecca T, McDermott, Gregory, Choi, Seung Hoan, Shoemaker, M Benjamin, Haas, Mary E, Weng, Lu-Chen, Lindsay, Mark E, Smith, J Gustav, Newton-Cheh, Christopher, Roden, Dan M, London, Barry, Wells, Quinn S, Ellinor, Patrick T, Kathiresan, Sekar, Lubitz, Steven A

“…BACKGROUND:Heart failure (HF) is a morbid and heritable disorder for which the biological mechanisms are incompletely understood. We therefore examined genetic…”
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Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells by Han, Lu, Li, Yang, Tchao, Jason, Kaplan, Aaron D, Lin, Bo, Li, You, Mich-Basso, Jocelyn, Lis, Agnieszka, Hassan, Narmeen, London, Barry, Bett, Glenna C L, Tobita, Kimimasa, Rasmusson, Randall L, Yang, Lei

“…Familial hypertrophic cardiomyopathy (HCM) is one the most common heart disorders, with gene mutations in the cardiac sarcomere. Studying HCM with…”
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Cardiac Implantable Electronic Device Infections: Who is at Greatest Risk? by Joy, Parijat Saurav, MD, MPH, Kumar, Gagan, MD, Poole, Jeanne E., MD, London, Barry, MD, PhD, Olshansky, Brian, MD

“…Abstract Background Cardiac Implantable Electronic Device (CIED) infections are associated with hospitalization, mortality, increased costs and adverse…”
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Genetics of Atrial Fibrillation by Feghaly, Julien, Zakka, Patrick, London, Barry, MacRae, Calum A, Refaat, Marwan M

“…Background Atrial fibrillation ( AF ) is a common arrhythmia seen in clinical practice. Occasionally, no common risk factors are present in patients with this…”
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Mechanism of automaticity in cardiomyocytes derived from human induced pluripotent stem cells by Kim, Jong J, Yang, Lei, Lin, Bo, Zhu, Xiaodong, Sun, Bin, Kaplan, Aaron D, Bett, Glenna C.L, Rasmusson, Randall L, London, Barry, Salama, Guy

“…Abstract Background and objectives. The creation of cardiomyocytes derived from human induced pluripotent stem cells (hiPS-CMs) has spawned broad excitement…”
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Deficiency of endothelial sirtuin1 in mice stimulates skeletal muscle insulin sensitivity by modifying the secretome by Li, Qiuxia, Zhang, Quanjiang, Kim, Young-Rae, Gaddam, Ravinder Reddy, Jacobs, Julia S., Bachschmid, Markus M., Younis, Tsneem, Zhu, Zhiyong, Zingman, Leonid, London, Barry, Rauckhorst, Adam J., Taylor, Eric B., Norris, Andrew W., Vikram, Ajit, Irani, Kaikobad

“…Downregulation of endothelial Sirtuin1 (Sirt1) in insulin resistant states contributes to vascular dysfunction. Furthermore, Sirt1 deficiency in skeletal…”
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Mutation in glycerol-3-phosphate dehydrogenase 1-like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias by LONDON, Barry, MICHALEC, Michael, BATY, Catherine J, LAGANA, Stephen, ALEONG, Ryan, GUTMANN, Rebecca, ACKERMAN, Michael J, MCNAMARA, Dennis M, WEISS, Raul, DUDLEY, Samuel C, MEHDI, Haider, XIAODONG ZHU, KERCHNER, Laurie, SANYAL, Shamarendra, VISWANATHAN, Prakash C, PFAHNL, Arnold E, SHANG, Lijuan L, MADHUSUDANAN, Mohan

“…Brugada syndrome is a rare, autosomal-dominant, male-predominant form of idiopathic ventricular fibrillation characterized by a right bundle-branch block and…”
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Current Perspectives on Coronavirus Disease 2019 and Cardiovascular Disease: A White Paper by the JAHA Editors by Gupta, Ajay K, Jneid, Hani, Addison, Daniel, Ardehali, Hossein, Boehme, Amelia K, Borgaonkar, Sanket, Boulestreau, Romain, Clerkin, Kevin, Delarche, Nicolas, DeVon, Holli A, Grumbach, Isabella M, Gutierrez, Jose, Jones, Daniel A, Kapil, Vikas, Maniero, Carmela, Mentias, Amgad, Miller, Pamela S, Ng, Sher May, Parekh, Jai D, Sanchez, Reynaldo H, Sawicki, Konrad Teodor, Te Riele, Anneline S J M, Remme, Carol Ann, London, Barry

“…Coronavirus Disease 2019 (COVID-19) has infected more than 3.0 million people worldwide and killed more than 200,000 as of April 27, 2020. In this White Paper,…”
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The role of GPD1L, a sodium channel interacting gene, in the pathogenesis of Brugada Syndrome by Greiner, Alexander M, Mehdi, Haider, Cevan, Chloe, Gutmann, Rebecca, London, Barry

“…Brugada Syndrome (BrS) is an inherited arrhythmia syndrome in which mutations in the cardiac sodium channel (Na 1.5) account for approximately 20% of cases…”
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Knockout of Sorbin And SH3 Domain Containing 2 (Sorbs2) in Cardiomyocytes Leads to Dilated Cardiomyopathy in Mice by McLendon, Jared M., Zhang, Xiaoming, Matasic, Daniel S., Kumar, Mohit, Koval, Olha M., Grumbach, Isabella M., Sadayappan, Sakthivel, London, Barry, Boudreau, Ryan L.

“…Background Sorbin and SH3 domain containing 2 (Sorbs2) protein is a cytoskeletal adaptor with an emerging role in cardiac biology and disease; yet, its…”
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Cardiac Arrhythmias: From (Transgenic) Mice to Men by London, Barry

“…Cardiac Arrhythmias. Transgenic and gene‐targeted mice now are frequently used to study cardiac arrhythmias due to the ease with which the mouse genome can be…”
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Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1-like gene (GPD1-L) mutations in sudden infant death syndrome by VAN NORSTRAND, David W, VALDIVIA, Carmen R, TESTER, David J, UEDA, Kazuo, LONDON, Barry, MAKIELSKI, Jonathan C, ACKERMAN, Michael J

“…Autopsy-negative sudden unexplained death, including sudden infant death syndrome, can be caused by cardiac channelopathies such as Brugada syndrome (BrS)…”
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Left Ventricular Diameter and Risk Stratification for Sudden Cardiac Death by Narayanan, Kumar, Reinier, Kyndaron, Teodorescu, Carmen, Uy‐Evanado, Audrey, Aleong, Ryan, Chugh, Harpriya, Nichols, Gregory A., Gunson, Karen, London, Barry, Jui, Jonathan, Chugh, Sumeet S.

“…Background Left ventricular (LV) diameter is routinely measured on the echocardiogram but has not been jointly evaluated with the ejection fraction (EF) for…”
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Cardiac Adverse Events Associated With Chemo-Radiation Versus Chemotherapy for Resectable Stage III Non-Small-Cell Lung Cancer: A Surveillance, Epidemiology and End Results-Medicare Study by Herbach, Emma, O'Rorke, Michael A, Carnahan, Ryan M, McDowell, Bradley D, Allen, Bryan, Grumbach, Isabella, London, Barry, Smith, Brian J, Spitz, Douglas R, Seaman, Aaron, Chrischilles, Elizabeth A

“…Background We compared cardiac outcomes for surgery-eligible patients with stage III non-small-cell lung cancer treated adjuvantly or neoadjuvantly with…”
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Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy by Refaat, Marwan M., MD, Lubitz, Steven A., MD, MPH, Makino, Seiko, MS, Islam, Zahid, MD, Frangiskakis, J. Michael, MD, PhD, Mehdi, Haider, PhD, Gutmann, Rebecca, RN, BSN, Zhang, Michael L., BS, Bloom, Heather L., MD, MacRae, Calum A., MB, ChB, PhD, Dudley, Samuel C., MD, PhD, Shalaby, Alaa A., MD, Weiss, Raul, MD, FHRS, McNamara, Dennis M., MD, London, Barry, MD, PhD, Ellinor, Patrick T., MD, PhD

“…Background Dilated cardiomyopathy (DCM) is a leading cause of heart failure and death. The etiology of DCM is genetically heterogeneous. Objectives We sought…”
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Estimated Cardiac Risk Associated With Macrolides and Fluoroquinolones Decreases Substantially When Adjusting for Patient Characteristics and Comorbidities by Polgreen, Linnea A., Riedle, Benjamin N., Cavanaugh, Joseph E., Girotra, Saket, London, Barry, Schroeder, Mary C., Polgreen, Philip M.

“…Background Some studies have found that antimicrobials, especially macrolides, increase the risk of cardiovascular death. We investigated potential…”
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