Search Results - "LOCKWOOD, C. Martin"

Plasma exchange in focal necrotizing glomerulonephritis without anti-GBM antibodies by Pusey, Charles D., Rees, Andrew J., Evans, David J., Peters, D. Keith, Lockwood, C. Martin

“…Plasma exchange in focal necrotizing glomerulonephritis without anti-GBM antibodies. To determine whether plasma exchange was of additional benefit in patients…”
Get full text

Autoantibodies to GBM and neutrophil cytoplasm in rapidly progressive glomerulonephritis by Jayne, David R.W., Marshall, Philip D., Jones, Sally J., Lockwood, C. Martin

“…Autoantibodies to GBM and neutrophil cytoplasm in rapidly progressive glomerulonephritis. The incidence of autoantibodies to glomerular basement membrane…”
Get full text

Monoclonal-Antibody Therapy in Systemic Vasculitis by Mathieson, Peter W, Cobbold, Stephen P, Hale, Geoffrey, Clark, Michael R, Oliveira, David B.G, Lockwood, C. Martin, Waldmann, Herman

“…MONOCLONAL antibodies are potentially useful therapeutic agents in a variety of immunologically mediated diseases, offering the theoretical advantage of…”
Get full text

Autoantibodies to myeloperoxidase in brown Norway rats treated with mercuric chloride by Esnault, V L, Mathieson, P W, Thiru, S, Oliveira, D B, Martin-Lockwood, C

“…Mercuric chloride (HgCl2) induces an autoimmune syndrome in Brown Norway (BN) rats characterized by the presence of a number of autoantibodies, including…”
Get more information

Myeloperoxidase autoantibodies distinguish vasculitis mediated by anti‐neutrophil cytoplasm antibodies from immune complex disease in MRL/Mp‐ lpr/lprmice: a spontaneous model for human microscopic angiitis by Harper, Janice M., Thiru, Sathia, Lockwood, C. Martin, Cooke, Anne

“…Anti‐neutrophil cytoplasm antibodies (ANCA) with specificity for myeloperoxidase (MPO) occur in the sera of patients with microscopic angiitis, an autoimmune…”
Get full text

Difficult Asthma or Churg-Strauss Syndrome? Steroids May Be Masking Undiagnosed Cases of Churg-Strauss Syndrome by D'Cruz, David P., Barnes, Neil C., Lockwood, C. Martin

Get full text

Antineutrophil cytoplasmic autoantibodies: the nephrologist's perspective by Lockwood, C M

“…Serologic tests for antineutrophil cytoplasmic autoantibodies (ANCA) provide diagnostic and prognostic information in patients with nephritis and systemic…”
Get more information

Serum soluble interleukin 2 receptor levels in anti-neutrophil cytoplasmic autoantibodies--positive systemic vasculitis by Lai, K. N., Lockwood, C. M.

“…Systemic vasculitis is characterized by the presence of autoantibodies to neutrophil cytoplasmic antigens (ANCA). The role of T-lymphocytes in systemic…”
Get full text

Antineutrophil cytoplasm autoantibodies and vasculitis by Zhao, M H, Short, A K, Lockwood, C M

“…Antineutrophil cytoplasm autoantibodies are useful diagnostic serologic markers for a variety of well-known primary vasculitic syndromes, including Wegener's…”
Get more information

Anti-neutrophil cytoplasm antibodies and anti-glomerular basement membrane antibodies: two coexisting distinct autoreactivities detectable in patients with rapidly progressive glomerulonephritis by Short, A K, Esnault, V L, Lockwood, C M

“…Circulating autoantibodies against the Goodpasture antigen (alpha 3 chain of type IV collagen) in the glomerular basement membrane (anti-GBM) and…”
Get more information

The inhibition of myeloperoxidase by ceruloplasmin can be reversed by anti-myeloperoxidase antibodies by Griffin, Siân V., Chapman, Philip T., Lianos, Elias A., Lockwood, C. Martin

“…Inhibition of myeloperoxidase by ceruloplasmin can be reversed by anti-myeloperoxidase antibodies. The purpose of this study was to characterize the recently…”
Get full text

Long-term remission of intractable systemic vasculitis with monoclonal antibody therapy by Lockwood, C M, Thiru, S, Isaacs, J D, Hale, G, Waldmann, H

“…Monoclonal antibodies that target T cells offer an alternative to conventional immunosuppressive drugs in the management of autoimmune disease. "Humanisation"…”
Get more information

Myeloperoxidase autoantibodies distinguish vasculitis mediated by anti-neutrophil cytoplasm antibodies from immune complex disease in MRL/Mp-lpr/lpr mice: a spontaneous model for human microscopic angiitis by Harper, J M, Thiru, S, Lockwood, C M, Cooke, A

“…Anti-neutrophil cytoplasm antibodies (ANCA) with specificity for myeloperoxidase (MPO) occur in the sera of patients with microscopic angiitis, an autoimmune…”
Get full text

Analysis of anti‐neutrophil cytoplasmic antibodies (ANCA): frequency and specificity in a sample of 191 homozygous (PiZZ) alpha1‐antitrypsin‐deficient subjects by Audrain, Marie A. P., Sesboüé, Richard, Baranger, Thierry A. R., Elliott, Jane, Testa, Angelo, Martin, Jean‐Pierre, Lockwood, C. Martin, Esnault, Vincent L. M.

“…Background. ANCA are autoantibodies directed against polymorphonuclear cell antigens, mainly proteinase 3 (PR3) and myeloperoxidase (MPO), which are implicated…”
Get full text

Difficult asthma or Churg-Strauss syndrome?: Steroids may be masking undiagnosed cases of Churg-Strauss syndrome by D'Cruz, David P, Barnes, Neil C, C Martin Lockwood

“…In any patient with asthma (especially late onset asthma that is difficult to control) with features of a multisystem disease it is worth considering an…”
Get full text

A comprehensive method to purify three major ANCA antigens: proteinase 3, myeloperoxidase and bactericidal/permeability-increasing protein from human neutrophil granule acid extract by Zhao, MingHui, Lockwood, C.Martin

“…Indirect immunofluorescence (IIF) techniques have shown that anti-neutrophil cytoplasm autoantibodies (ANCA) are useful serological markers for certain small…”
Get full text

ANCA anti-idiotype antibodies and the treatment of systemic vasculitis with intravenous immunoglobulin by Jayne, D R, Esnault, V L, Lockwood, C M

“…The presence of anti-idiotype antibodies (anti-id) to anti-neutrophil cytoplasm autoantibodies (ANCA) in intravenous immunoglobulin (IVIg) and remission sera…”
Get more information

Analysis of anti-neutrophil cytoplasmic antibodies (ANCA) : frequency and specificity in a sample of 191 homozygous (PIZZ) alphal-antitrypsin-deficient subjects by AUDRAIN, Marie A. P, SESBOÜE, Richard, BARANGER, Thierry A. R, ELLIOTT, Jane, TESTA, Angelo, MARTIN, Jean-Pierre, LOCKWOOD, C. Martin, ESNAULT, Vincent L. M

Get full text

Distribution of MHC class II alleles in primary systemic vasculitis by Zhang, Li, Jayne, David R.W., Zhao, Ming H., Lockwood, C. Martin, Oliveira, David B.G.

“…Distribution of MHC class II alleles in primary systemic vasculitis. Previous studies have shown a number of different associations between major…”
Get full text

Immunoregulation of mercuric chloride-induced autoimmunity in Brown Norway rats: a role for CD8+ T cells revealed by in vivo depletion studies by Mathieson, P W, Stapleton, K J, Oliveira, D B, Lockwood, C M

“…Mercuric chloride (HgCl2) induces the production of autoantibodies to glomerular basement membrane (GBM) in the Brown Norway (BN) rat. The autoimmune response…”
Get more information