Search Results - "LOCKWOOD, A P"

Model-based Drug Development by Lalonde, R L, Kowalski, K G, Hutmacher, M M, Ewy, W, Nichols, D J, Milligan, P A, Corrigan, B W, Lockwood, P A, Marshall, S A, Benincosa, L J, Tensfeldt, T G, Parivar, K, Amantea, M, Glue, P, Koide, H, Miller, R

“…The low productivity and escalating costs of drug development have been well documented over the past several years. Less than 10% of new compounds that enter…”
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Tyrosine Improves Working Memory in a Multitasking Environment by Thomas, John R, Lockwood, Park A, Singh, Anita, Deuster, Patricia A

“…Previous studies indicate that tyrosine may prove useful in promoting improved performance in situations in which performance is compromised by stress. To…”
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The prepuce: specialized mucosa of the penis and its loss to circumcision by Taylor, J R, Lockwood, A P, Taylor, A J

“…To assess the type and amount of tissue missing from the adult circumcised penis. The gross and histological features of the prepuces of 22 adults obtained at…”
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Comparison and cross-validation of cycle ergometry estimates of VO2max by LOCKWOOD, P. A, YODER, J. E, DEUSTER, P. A

“…The purpose of this study was to examine the accuracy and quality of a series of cycle ergometry tests used to estimate maximal aerobic capacity (VO2max)…”
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Differential effects of ketamine isomers on neuronal and extraneuronal catecholamine uptake mechanisms by LUNDY, P. M, LOCKWOOD, P. A, THOMPSON, G, FREW, R

“…Contractile responses of isolated rabbit aortic strips to epinephrine and norepinephrine were potentiated in a dose-related manner by (+) ketamine but not by…”
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The use of clinical trial simulation to support dose selection: Application to development of a new treatment for chronic neuropathic pain by LOCKWOOD, Peter A, COOK, Jack A, EWY, Wayne E, MANDEMA, Jaap W

“…Pregabalin is being evaluated for the treatment of neuropathic pain. Two phase 2 studies were simulated to determine how precisely the dose that caused a…”
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The involvement of sodium transport in the volume regulation of the amphipod crustacean, Gammarus duebeni by Lockwood, A P

“…The effect on sodium influx of reduction in the fluid volume of the amphipod Gammarus duebeni has been investigated. Removal of water and sodium by exposure to…”
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In vitro Toxicity of T-2 Mycotoxin in Mouse Lymphoid Cells by DiNINNO, V. L, PENMAN, D, BHATTI, A. R, ERHARDT, N. P, LOCKWOOD, P. A

“…Preventive Medicine Section, Defence Research Establishment Suffield, Ralston, Alberta T0J 2N0, Canada ABSTRACT Summary: The in vitro toxicity of T-2 toxin…”
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ACTIVATION OF THE SODIUM UPTAKE SYSTEM AT HIGH BLOOD CONCENTRATIONS IN THE AMPHIPOD GAMMARUS DUEBENI by LOCKWOOD, A P

“…Some factors responsible for eliciting an increase in the rate of active uptake of sodium by Gammarus duebeni have been studied. Animals previously…”
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Aliens and interlopers at sea by Lockwood, A P

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Studies on the absorption and metabolism of D-(u-14C) glucose by Polymorphus minutus (Acanthocephala) in vitro by Crompton, D W, Lockwood, A P

“…The absorption and initial metabolism of glucose by the acanthocephalan Polymorphus minutus have been studied in vitro under conditions designed to approximate…”
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The electrical potential difference across the epithelium of isolated gills of the crayfish Austropotamobius pallipes (Lereboullet) by Croghan, P C, Curra, R A, Lockwood, A P

“…A technique is described for recording the electrical potential differences across the epithelium (epithelial potential) of isolated podobranch gills of…”
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Composition of the Blood in Onychophora by ROBSON, E. A, LOCKWOOD, A. P. M, RALPH, R

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Human resource planning: the role of the personnel practitioner by Lockwood, P A

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Milner's Entry into the War Cabinet, December 1916 by Lockwood, P. A.

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HI-6, an oxime which is an effective antidote of soman poisoning: a structure-activity study by Clement, J G, Lockwood, P A

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Potency of N6-modified N-alkyl adenosine-5'-uronamides at presynaptic adenosine receptors in guinea-pig ileum by PATON, D. M, LOCKWOOD, P. A, MARTLEW, D. L, OLSSON, R. A

“…The ability of a series of N6-modified N-alkyl-5'-uronamides to cause presynaptic inhibition of transmitter release was examined in isolated guinea-pig ileum…”
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Population exposure response analysis of pregabalin in patients with generalized anxiety disorder (GAD) by Lockwood, P. A., Kowalski, K. G., Corrigan, B. W.

“…Purpose To describe the exposure‐response relationship of pregabalin in patients with generalized anxiety disorder (GAD). Methods A subject‐specific random…”
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Case of Popliteal Aneurism a Second Time Treated Successfully by Compression by Lockwood, A P

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The acetylcholinesterase reactivator HI-6 (1-[[[4-(aminocarbonyl)pyridinio]methoxy]methyl]-2-[(hydroxyimino)methyl]-pyridinium dichloride): a comparative study of HI-6 samples from various sources by CLEMENT, J. G, LOCKWOOD, P. A, THOMPSON, H. G

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