Search Results - "LOBET, Y"

Simultaneous presence of different Borrelia burgdorferi genospecies in biological fluids of Lyme disease patients by DEMAERSCHALCK, I, ABDELOUAHID BEN MESSAOUD, DE KESEL, M, HOYOIS, B, LOBET, Y, HOET, P, BIGAIGNON, G, BOLLEN, A, GODFROID, E

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Prospects for a better vaccine against tuberculosis by Reed, S.G., Alderson, M.R., Dalemans, W., Lobet, Y., Skeiky, Y.A.W.

“…There have been many new promising approaches to developing human vaccines against tuberculosis (TB). Advances in gene and antigen identification, availability…”
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Inhibition of Borrelia burgdorferi-Tick Interactions In Vivo by Outer Surface Protein A Antibody by Pal, Utpal, Montgomery, Ruth R, Lusitani, Denise, Voet, Pierre, Weynants, Vincent, Malawista, Stephen E, Lobet, Yves, Fikrig, Erol

“…Borrelia burgdorferi outer surface protein (Osp) A is preferentially expressed by spirochetes in the Ixodes scapularis gut and facilitates pathogen-vector…”
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Transmission of Borrelia garinii OspA serotype 4 to BALB/c mice by Ixodes ricinus ticks collected in the field by HU, C. M, WILSKE, B, FINGERLE, V, LOBET, Y, GERN, L

“…In Europe, Borrelia garinii OspA serotype 4 has been isolated from the cerebrospinal fluid of patients but, up to now, has never been identified among culture…”
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Developing a nontypeable Haemophilus influenzae (NTHi) vaccine by Poolman, J.T., Bakaletz, L., Cripps, A., Denoel, P.A., Forsgren, A., Kyd, J., Lobet, Y.

“…There is a current high demand for nontypable Haemophilus influenzae (NTHi) vaccines. Various options for the composition of such vaccines are possible…”
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Evaluation of genetic divergence among Borrelia burgdorferi isolates by use of OspA, fla, HSP60, and HSP70 gene probes by Wallich, R, Helmes, C, Schaible, U E, Lobet, Y, Moter, S E, Kramer, M D, Simon, M M

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An effective vaccine against Lyme disease by Crooy, P, Lobet, Y

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Evaluation of the safety, reactogenicity and immunogenicity of three recombinant outer surface protein (OspA) lyme vaccines in healthy adults by Van Hoecke, C., Comberbach, M., De Grave, D., Desmons, P., Fu, D., Hauser, P., Lebacq, E., Lobet, Y., Voet, P.

“…The safety, reactogenicity and immunogenicity of three candidate Lyme vaccines based on recombinant outer surface protein (OspA) presented in either lipidated…”
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Antigenic Conservation of an Immunodominant Invariable Region of the VlsE Lipoprotein among European Pathogenic Genospecies of Borrelia burgdorferi SL by Liang, Fang Ting, Aberer, Elisabeth, Cinco, Marina, Gern, Lise, Hu, Chang Min, Lobet, Yves N., Ruscio, Maurizio, Voet, Pierre E., Weynants, Vincent E., Philipp, Mario T.

“…Lyme disease is caused by genetically divergent spirochetes, including 3 pathogenic genospecies: Borrelia burgdorferi sensu stricto, B. garinii, and B…”
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Reactivity with a specific epitope of outer surface protein A predicts protection from infection with the Lyme disease spirochete, Borrelia burgdorferi by GOLDE, W. T, PIESMAN, J, FRANTZ, J. C, DOLAN, M. C, KRAMER, M, HAUSER, P, LOBET, Y, CAPIAU, C, DESMONS, P, VOET, P, DEARWESTER, D

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Site-specific alterations in the B oligomer that affect receptor-binding activities and mitogenicity of pertussis toxin by LOBET, Y, FERON, C, DEQUESNE, G, SIMOEN, E, HAUSER, P, LOCHT, C

“…Pertussis toxin plays a major role in the pathogenesis of whooping cough and is considered an important constituent of vaccines against this disease. It is…”
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Effect of site-directed mutagenic alterations on ADP-ribosyltransferase activity of the A subunit of Escherichia coli heat-labile enterotoxin by LOBET, T, CLUFF, C. W, CIEPLAK, W. JR

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Tick transmission of Borrelia burgdorferi to inbred strains of mice induces an antibody response to P39 but not to outer surface protein A by GOLDE, W. T, KAPPEL, K. J, DEQUESNE, G, FERON, C, PLAINCHAMP, D, CAPIAU, C, LOBET, Y

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Efficacy of Human Lyme Disease Vaccine Formulations in a Mouse Model by Telford, S. R., Kantor, F. S., Lobet, Y., Barthold, S. W., Spielman, A., Flavell, R. A., Fikrig, E.

“…Although immunization with recombinant outer surface protein A (OspA) appears to protect mice against infection by the agent of Lyme disease, all reported…”
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Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice by Fikrig, Erol, Flavell, Richard A, Alexopoulou, Lena, Thomas, Venetta, Schnare, Markus, Lobet, Yves, Anguita, Juan, Schoen, Robert T, Medzhitov, Ruslan

“…The Lyme disease vaccine is based on the outer-surface lipoprotein (OspA) of the pathogen Borrelia burgdorferi, and 95% of vaccine recipients develop…”
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Immunization of mice by recombinant OspA preparations and protection against Borrelia burgdorferi infection induced by Ixodes ricinus tick bites by Gern, L, Rais, O, Capiau, C, Hauser, P, Lobet, Y, Simoen, E, Voet, P, Pêtre, J

“…The wide distribution of Borrelia burgdorferi, the spirochete causing Lyme borreliosis, represents a human health hazard in many areas of the world…”
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Differential Immune Responses and Protective Efficacy Induced by Components of a Tuberculosis Polyprotein Vaccine, Mtb72F, Delivered as Naked DNA or Recombinant Protein by Skeiky, Yasir A. W, Alderson, Mark R, Ovendale, Pamela J, Guderian, Jeffrey A, Brandt, Lise, Dillon, Davin C, Campos-Neto, Antonio, Lobet, Yves, Dalemans, Wilfried, Orme, Ian M, Reed, Steven G

“…Key Ags of Mycobacterium tuberculosis initially identified in the context of host responses in healthy purified protein derivative-positive donors and infected…”
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Expression, refolding and crystallization of the OpcA invasin from Neisseria meningitidis by Prince, S. M., Feron, C., Janssens, D., Lobet, Y., Achtman, M., Kusecek, B., Bullough, P. A., Derrick, J. P.

“…OpcA is an integral outer membrane from the Gram‐negative pathogen Neisseria meningitidis that plays a role in adhesion of meningococci to host cells. The…”
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Development of a vaccine against Lyme disease by Lobet, Y.

“…A vaccine against Lyme disease has been successfully tested in US endemie areas. It is based on the use of OspA, an outer surface protein of B. burgdorferi, to…”
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Tuberculosis vaccine development; from mouse to man by Reed, Steven, Lobet, Yves

“…A tuberculosis (TB) vaccine candidate, Mtb72, was developed following an antigen discovery program involving a combination of expression cloning strategies and…”
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