Search Results - "LJILJANA I. DOŠEN-MIĆOVIĆ"
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Antiproliferative activity of NCI-DTP glutarimide derivatives. An alignment independent 3D QSAR study
Published in Journal of the Serbian Chemical Society (01-01-2010)“…Alignment-free, three dimensional structure–activity relationships (3D QSAR) of the antiproliferative potency of twenty-two glutarimide-containing compounds,…”
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Molecular modelling of fentanyl analogs
Published in Journal of the Serbian Chemical Society (01-01-2004)“…Fentanyl is a highly potent and clinically widely used narcotic analgesic. A large number of its analogs have been synthesized, some of which (sufentanil and…”
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The synthesis and preliminary pharmacological evaluation of racemic cis and trans 3-alkylfentanyl analogues
Published in Journal of the Serbian Chemical Society (01-01-2004)“…A general, five step method for the synthesis of 3-alkylfentanyl analogues (i.e., cis and trans 3-alkyl-4-anilidopiperidines 6.1–6.6) has been developed. The…”
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Stereoselective free radical phenylsulfenylation of a nonactivated δ-carbon atom
Published in Journal of the Serbian Chemical Society (01-01-2004)“…A stereoselective free radical introduction of a phenylthio group onto a nonactivated methyl group in the δ-position, adjacent to a prochiral carbon atom, was…”
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The synthesis and pharmacological evaluation of (±)-2, 3- seco-fentanyl analogues
Published in Journal of the Serbian Chemical Society (01-01-2004)“…An efficient, five-step synthetic approach to various acyclic 1,3-diamines has been developed and applied to the preparation of a novel class of open-chained…”
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An optimized synthesis of a key pharmaceutical intermediate methyl 4-[(1-oxopropyl)phenylamino]piperidine-4-carboxylate
Published in Journal of the Serbian Chemical Society (01-01-2002)“…An efficient synthesis of methyl 4-[(1-oxopropyl)phenylamino]piperidine-4-carboxylate (7) has been developed starting from 1-benzylpiperidin-4-one (1). The…”
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Oxidation of steroidal 5-en-3 beta-ols with Jones reagent in ether
Published in Steroids (01-05-1994)“…The two-phase oxidation of steroidal 5-en-3 beta-ol (via 5-en-3-ones) into corresponding 4-en-3,6-diones in diethyl ether with Jones reagent was investigated…”
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