Search Results - "LIVINGSTON, Robert J"

Using synthetic templates to design an unbiased multiplex PCR assay by Carlson, Christopher S., Emerson, Ryan O., Sherwood, Anna M., Desmarais, Cindy, Chung, Moon-Wook, Parsons, Joseph M., Steen, Michelle S., LaMadrid-Herrmannsfeldt, Marissa A., Williamson, David W., Livingston, Robert J., Wu, David, Wood, Brent L., Rieder, Mark J., Robins, Harlan

“…T and B cell receptor loci undergo combinatorial rearrangement, generating a diverse immune receptor repertoire, which is vital for recognition of potential…”
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Genomic regions exhibiting positive selection identified from dense genotype data by Carlson, Christopher S, Thomas, Daryl J, Eberle, Michael A, Swanson, Johanna E, Livingston, Robert J, Rieder, Mark J, Nickerson, Deborah A

“…The allele frequency spectrum of polymorphisms in DNA sequences can be used to test for signatures of natural selection that depart from the expected frequency…”
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Linkage disequilibrium in wild mice by Laurie, Cathy C, Nickerson, Deborah A, Anderson, Amy D, Weir, Bruce S, Livingston, Robert J, Dean, Matthew D, Smith, Kimberly L, Schadt, Eric E, Nachman, Michael W

“…Crosses between laboratory strains of mice provide a powerful way of detecting quantitative trait loci for complex traits related to human disease. Hundreds of…”
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Comprehensive identification and characterization of diallelic insertion–deletion polymorphisms in 330 human candidate genes by Bhangale, Tushar R., Rieder, Mark J., Livingston, Robert J., Nickerson, Deborah A.

“…Despite being the second most frequent type of polymorphism in the genome, diallelic insertion–deletion polymorphisms (indels) have received far less attention…”
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Variants of Concern Are Overrepresented Among Postvaccination Breakthrough Infections of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Washington State by McEwen, Abbye E, Cohen, Seth, Bryson-Cahn, Chloe, Liu, Catherine, Pergam, Steven A, Lynch, John, Schippers, Adrienne, Strand, Kathy, Whimbey, Estella, Mani, Nandita S, Zelikoff, Allison J, Makarewicz, Vanessa A, Brown, Elizabeth R, Bakhash, Shah A Mohamed, Baker, Noah R, Castor, Jared, Livingston, Robert J, Huang, Meei-Li, Jerome, Keith R, Greninger, Alexander L, Roychoudhury, Pavitra

“…Abstract Across 20 vaccine breakthrough cases detected at our institution, all 20 (100%) infections were due to variants of concern (VOCs) and had a median Ct…”
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Deep sequencing of the human TCRγ and TCRβ repertoires suggests that TCRβ rearranges after αβ and γδ T cell commitment by Sherwood, Anna M, Desmarais, Cindy, Livingston, Robert J, Andriesen, Jessica, Haussler, Maximilian, Carlson, Christopher S, Robins, Harlan

“…T lymphocytes respond to a broad array of pathogens with the combinatorial diversity of the T cell receptor (TCR). This adaptive response is possible because…”
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Clinical Performance Characteristics of the Swift Normalase Amplicon Panel for Sensitive Recovery of Severe Acute Respiratory Syndrome Coronavirus 2 Genomes by Shrestha, Lasata, Lin, Michelle J, Xie, Hong, Mills, Margaret G, Mohamed Bakhash, Shah A, Gaur, Vinod P, Livingston, Robert J, Castor, Jared, Bruce, Emily A, Botten, Jason W, Huang, Meei-Li, Jerome, Keith R, Greninger, Alexander L, Roychoudhury, Pavitra

“…Amplicon-based sequencing methods are central in characterizing the diversity, transmission, and evolution of severe acute respiratory syndrome coronavirus 2…”
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Integrating host genomics with surveillance for invasive bacterial diseases by Crawford, Dana C, Zimmer, Shanta M, Morin, Craig A, Messonnier, Nancy E, Lynfield, Ruth, Yi, Qian, Shephard, Cynthia, Wong, Michelle, Rieder, Mark J, Livingston, Robert J, Nickerson, Deborah A, Whitney, Cynthia G, Lingappa, Jairam

“…We tested the feasibility of linking Active Bacterial Core surveillance, a prospective, population-based surveillance system for invasive bacterial disease, to…”
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Pattern of sequence variation across 213 environmental response genes by Livingston, Robert J, von Niederhausern, Andrew, Jegga, Anil G, Crawford, Dana C, Carlson, Christopher S, Rieder, Mark J, Gowrisankar, Sivakumar, Aronow, Bruce J, Weiss, Robert B, Nickerson, Deborah A

“…To promote the clinical and epidemiological studies that improve our understanding of human genetic susceptibility to environmental exposure, the Environmental…”
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Deep sequencing with intronic capture enables identification of an APC exon 10 inversion in a patient with polyposis by Shirts, Brian H., Salipante, Stephen J., Casadei, Silvia, Ryan, Shawnia, Martin, Judith, Jacobson, Angela, Vlaskin, Tatyana, Koehler, Karen, Livingston, Robert J., King, Mary-Claire, Walsh, Tom, Pritchard, Colin C.

“…Purpose: Single-exon inversions have rarely been described in clinical syndromes and are challenging to detect using Sanger sequencing. We report the case of a…”
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Effects of ammonia in pulp mill effluents on estuarine phytoplankton assemblages: field descriptive and experimental results by Livingston, Robert J, Prasad, Akshithala K, Niu, Xufeng, McGlynn, Sean E

“…A field descriptive and field/laboratory experimental program was carried out to evaluate the effects of ammonia (NH 3) discharged by a pulp mill on estuarine…”
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The Environmental Genome Project: Reference Polymorphisms for Drug Metabolism Genes and Genome-Wide Association Studies by Rieder, Mark J., Livingston, Robert J., Stanaway, Ian B., Nickerson, Deborah A.

“…The Environmental Genome Project (EGP) has generated a comprehensive resource of commonly occurring single nucleotide polymorphisms (SNPs) in more than six…”
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Freshwater Input to a Gulf Estuary: Long-Term Control of Trophic Organization by Livingston, Robert J., Niu, Xufeng, Lewis, F. Graham, Woodsum, Glenn C.

“…A long-term (9.5 yr) study addressed the relationship of the trophic organization of a river-dominated Gulf of Mexico estuary with interannual trends of…”
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LPA and PLG sequence variation and kringle IV-2 copy number in two populations by Crawford, Dana C, Peng, Ze, Cheng, Jan-Fang, Boffelli, Dario, Ahearn, Magdalena, Nguyen, Dan, Shaffer, Tristan, Yi, Qian, Livingston, Robert J, Rieder, Mark J, Nickerson, Deborah A

“…Lp(a) levels have long been recognized as a potential risk factor for coronary heart disease that is almost completely under genetic control. Much of the…”
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Allelic spectrum of the natural variation in CRP by CRAWFORD, Dana C, QIAN YI, SMITH, Joshua D, SHEPHARD, Cynthia, WONG, Michelle, WITRAK, Laura, LIVINGSTON, Robert J, RIEDER, Mark J, NICKERSON, Deborah A

“…With the recent completion of the International HapMap Project, many tools are in hand for genetic association studies seeking to test the common…”
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Sequence diversity, natural selection and linkage disequilibrium in the human T cell receptor alpha/delta locus by MACKELPRANG, Rachel, LIVINGSTON, Robert J, EBERLE, Michael A, CARLSON, Christopher S, QIAN YI, AKEY, Joshua M, NICKERSON, Deborah A

“…T cell receptors (TR), through their interaction with the major histocompatibility complex, play a central role in immune responsiveness and potentially…”
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Sequence variation in the human T-cell receptor loci by Mackelprang, Rachel, Carlson, Christopher S., Subrahmanyan, Lakshman, Livingston, Robert J., Eberle, Michael A., Nickerson, Deborah A.

“…Identifying common sequence variations known as single nucleotide polymorphisms (SNPs) in human populations is one of the current objectives of the human…”
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An Overview of the Environmental Genome Project by Nickerson, Deborah A, Rieder, Mark J, Livingston, Robert J

“…The Environmental Genome Project was borne out of a historic conference convened by NIEHS in October 1997. The project is designed to explore the relationship…”
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Factors controlling seagrass growth in a gulf coastal system: Water and sediment quality and light by Livingston, Robert J, McGlynn, Sean E, Niu, Xufeng

“…A combined field descriptive/experimental and laboratory experimental study was carried out to determine the relationships of water quality, qualitative and…”
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Expression of a Truncated Keratin 5 May Contribute to Severe Palmar–Plantar Hyperkeratosis in Epidermolysis Bullosa Simplex Patients by Livingston, Robert J., Sybert, Virginia P., Smith, Lynne T., Dale, Beverly A., Presland, Richard B., Stephens, Karen

“…Epidermolysis bullosa simplex are dominant disorders of skin fragility characterized by intraepidermal blistering upon mild mechanical trauma. Skin fragility…”
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