Search Results - "LIVINGSTON, David J."

Fertility protection during chemotherapy treatment by boosting the NAD(P)+ metabolome by Ho, Wing-Hong Jonathan, Marinova, Maria B, Listijono, Dave R, Bertoldo, Michael J, Richani, Dulama, Kim, Lynn-Jee, Brown, Amelia, Riepsamen, Angelique H, Cabot, Safaa, Frost, Emily R, Bustamante, Sonia, Zhong, Ling, Selesniemi, Kaisa, Wong, Derek, Madawala, Romanthi, Marchante, Maria, Goss, Dale M, Li, Catherine, Araki, Toshiyuki, Livingston, David J, Turner, Nigel, Sinclair, David A, Walters, Kirsty A, Homer, Hayden A, Gilchrist, Robert B, Wu, Lindsay E

“…Chemotherapy induced ovarian failure and infertility is an important concern in female cancer patients of reproductive age or younger, and non-invasive,…”
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Dysregulated nicotinamide adenine dinucleotide metabolome in patients hospitalized with COVID-19 by Valderrábano, Rodrigo J, Wipper, Benjamin, Pencina, Karol Mateusz, Migaud, Marie, Shang, Yili Valentine, Latham, Nancy K, Montano, Monty, Cunningham, James M, Wilson, Lauren, Peng, Liming, Memish-Beleva, Yusnie, Bhargava, Avantika, Swain, Pamela M, Lehman, Phoebe, Lavu, Siva, Livingston, David J, Bhasin, Shalender

“…Nicotinamide adenine dinucleotide (NAD ) depletion has been postulated as a contributor to the severity of COVID-19; however, no study has prospectively…”
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Knowledge base and practice among clinicians regarding oral anticoagulant therapy: A questionnaire survey by J D David Livingston, M Joseph John

“…Purpose: To assess the knowledge of clinicians regarding various aspects of anticoagulant therapy. Materials and Methods: This cross-sectional study was done…”
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389 : Fertility Preservation During Chemotherapy Treatment by NAD+ Repletion in Mice by Gilchrist, Robert, Ho, Wing-Hong Jonathan, Marinova, Maria B, Listijono, Dave R, Bertoldo, Michael J, Richani, Dulama, Lynn-Jee, Kim, Brown, Amelia, Riepsamen, Angelique H, Cabot, Safaa, Bustamante, Sonia, Zhong, Ling, Selesniemi, Kaisa, Wong, Derek, Goss, Dale M, Li, Catherine, Araki, Toshiyuki, Livingston, David J, Turner, Nigel, Sinclair, David A, Walters, Kirsty A, Homer, Hayden A, Wu, Lindsay E

“…Background and Aims: Chemotherapy induced ovarian failure and infertility is an important concern in female cancer patients of reproductive age or younger, and…”
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Activation of Interferon-γ Inducing Factor Mediated by Interleukin-1β Converting Enzyme by Gu, Yong, Kuida, Keisuke, Tsutsui, Hiroko, Ku, George, Hsiao, Kathy, Fleming, Mark A., Hayashi, Nobuki, Higashino, Kazuya, Okamura, Haruki, Nakanishi, Kenji, Kurimoto, Masashi, Tanimoto, Tadao, Flavell, Richard A., Sato, Vicki, Harding, Matthew W., Livingston, David J., Michael S.-S. Su

“…The interleukin-1β (IL-1β) converting enzyme (ICE) processes the inactive IL-1β precursor to the proinflammatory cytokine. ICE was also shown to cleave the…”
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Structure and mechanism of interleukin-lβ converting enzyme by Wilson, Keith P, Black, Jo-Anne F, Thomson, John A, Kim, Eunice E, Griffith, James P, Navia, Manuel A, Murcko, Mark A, Chambers, Stephen P, Aldape, Robert A, Raybuck, Scott A, Livingston, David J

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Inhibition of IMPDH by Mycophenolic Acid:  Dissection of Forward and Reverse Pathways Using Capillary Electrophoresis by Fleming, Mark A, Chambers, Stephen P, Connelly, Patrick R, Nimmesgern, Elmar, Fox, Ted, Bruzzese, Frank J, Hoe, Stephen T, Fulghum, John R, Livingston, David J, Stuver, Cameron M, Sintchak, Michael D, Wilson, Keith P, Thomson, John A

“…The objective of this work was to contribute to the understanding of mechanisms for IMPDH inhibition. We over-expressed hamster type II IMPDH in Escherichia…”
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FKBP12 Binds the Inositol 1,4,5-Trisphosphate Receptor at Leucine-Proline (1400–1401) and Anchors Calcineurin to this FK506-like Domain by Cameron, Andrew M., Nucifora, Frederick C., Fung, Eric T., Livingston, David J., Aldape, Robert A., Ross, Christopher A., Snyder, Solomon H.

“…The immunophilin FKBP12 is one of the most abundant and conserved proteins in biology. It is the primary receptor for the immunosuppressant actions of the drug…”
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8-Hydroxy-5-deazaflavin-reducing hydrogenase from Methanobacterium thermoautotrophicum: 1. Purification and characterization by Fox, Judith A, Livingston, David J, Orme-Johnson, William H, Walsh, Christopher T

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Kinetic Characterization of Human Immunodeficiency Virus Type-1 Protease-resistant Variants by Pazhanisamy, S, Stuver, C M, Cullinan, A B, Margolin, N, Rao, B G, Livingston, D J

“…Passage of human immunodeficiency virus type-1 (HIV-1) in T-lymphocyte cell lines in the presence of increasing concentrations of the hydroxylethylamino…”
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Myoglobin Diffusion in Bovine Heart Muscle by Livingston, David J., La Mar, Gerd N., Brown, W. Duane

“…The rotational mobility of myoglobin in situ was determined by proton nuclear magnetic resonance line width measurements of a characteristic myoglobin…”
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Pharmacokinetics in Chimpanzees of Recombinant Human Tissue-Type Plasminogen Activator Produced in Mouse C127 and Chinese Hamster Ovary Cells by TANIGAWARA, Yusuke, HORI, Ryohei, OKUMURA, Kazuo, TSUJI, Jun-ichi, SHIMIZU, Norihide, NOMA, Seiji, SUZUKI, Junko, LIVINGSTON, David J., RICHARDS, Susan M., KEYES, Lynne D., COUCH, Ronald C., ERICKSON, Mary K.

“…Pharmacokinetics of recombinant tissue-type plasminogen activator (rt-PA) produced in mouse C127 cells (t-PA(C127)) and Chinese hamster ovary cells (t-PA(CHO))…”
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Relevance of Plasma Protein Binding to Antiviral Activity and Clinical Efficacy of Inhibitors of Human Immunodeficiency Virus Protease by Bilello, John A., Drusano, George L.

“…Livingston et al. [1] recently reported on the effects of plasma protein binding on the anti-human immunodeficiency virus (HIV) activity of the protease…”
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NAD+ precursors prolong survival and improve cardiac phenotypes in a mouse model of Friedreich's Ataxia by Perry, Caroline E, Halawani, Sarah M, Mukherjee, Sarmistha, Ngaba, Lucie V, Lieu, Melissa, Lee, Won Dong, Davis, James G, Adzika, Gabriel K, Bebenek, Alyssa N, Bazianos, Daniel D, Chen, Beishan, Mercado-Ayon, Elizabeth, Flatley, Liam P, Suryawanshi, Arjun P, Ho, Isabelle, Rabinowitz, Joshua D, Serai, Suraj D, Biko, David M, Tamaroff, Jaclyn, DeDio, Anna, Wade, Kristin, Lin, Kimberly Y, Livingston, David J, McCormack, Shana E, Lynch, David R, Baur, Joseph A

“…Friedreich's ataxia (FRDA) is a progressive disorder caused by insufficient expression of frataxin, which plays a critical role in assembly of iron-sulfur…”
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A mutational analysis of the active site of human type II inosine 5′-monophosphate dehydrogenase by Futer, Olga, Sintchak, Michael D., Caron, Paul R., Nimmesgern, Elmar, DeCenzo, Maureen T., Livingston, David J., Raybuck, Scott A.

“…The oxidation of IMP to XMP is the rate-limiting step in the de novo synthesis of guanine ribonucleotides. This NAD-dependent reaction is catalyzed by the…”
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FK506 Binding Protein Mutational Analysis by Futer, Olga, DeCenzo, Maureen T., Aldape, Robert A., Livingston, David J.

“…The 12- and 13-kDa FK506 binding proteins (FKBP12 and FKBP13) are cis-trans peptidyl-prolyl isomerases that bind the macrolides FK506 (Tacrolimus) and…”
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Human ICE/CED-3 Protease Nomenclature by Alnemri, Emad S, Livingston, David J, Nicholson, Donald W, Salvesen, Guy, Thornberry, Nancy A, Wong, Winnie W, Yuan, Junying

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Solution Structure of FK506 Bound to the R42K, H87V Double Mutant of FKBP-12 by Lepre, Christopher A, Pearlman, David A, Cheng, Jya-Wei, DeCenzo, Maureen T, Moore, Jonathan M, Livingston, David J

“…The binding of the FK506/FKBP-12 complex to calcineurin (CN), its putative target for immunosuppression, involves recognition of solvent-exposed regions of the…”
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A Modified Human Tissue Plasminogen Activator with Extended Half-Life In Vivo by Lau, David, Kuzma, Gregory, Wei, Cha-Mer, Livingston, David J, Hsiung, Nancy

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Altered Cytokine Export and Apoptosis in Mice Deficient in Interleukin-1β Converting Enzyme by Kuida, Keisuke, Lippke, Judith A., Ku, George, Harding, Matthew W., Livingston, David J., Michael S.-S. Su, Flavell, Richard A.

“…The interleukin-1β (IL-1β) converting enzyme (ICE) processes the inactive IL-1β precursor to the proinflammatory cytokine. Adherent monocytes from mice…”
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