Search Results - "LIU, Stanley K"
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1
Molecular landmarks of tumor hypoxia across cancer types
Published in Nature genetics (01-02-2019)“…Many primary-tumor subregions have low levels of molecular oxygen, termed hypoxia. Hypoxic tumors are at elevated risk for local failure and distant…”
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2
PD-L1 Immunohistochemistry Assay Concordance in Urothelial Carcinoma of the Bladder and Hypopharyngeal Squamous Cell Carcinoma
Published in The American journal of surgical pathology (01-08-2018)“…Programmed death ligand-1 (PD-L1) immunohistochemistry is used to guide treatment decisions regarding the use of checkpoint immunotherapy in the management of…”
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3
Targeting of CCBE1 by miR-330-3p in human breast cancer promotes metastasis
Published in British journal of cancer (09-05-2017)“…Background: MicroRNAs (miRs) are involved in the regulation of many processes that contribute to malignancy, including cell proliferation, radiation…”
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4
microRNAs identified in prostate cancer: Correlative studies on response to ionizing radiation
Published in Molecular cancer (23-03-2020)“…As the most frequently diagnosed non-skin cancer in men and a leading cause of cancer-related death, understanding the molecular mechanisms that drive…”
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5
miRNA-95 Mediates Radioresistance in Tumors by Targeting the Sphingolipid Phosphatase SGPP1
Published in Cancer research (Chicago, Ill.) (01-12-2013)“…Radiation resistance poses a major clinical challenge in cancer treatment, but little is known about how microRNA (miR) may regulate this phenomenon. In this…”
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6
Prostate cancer reshapes the secreted and extracellular vesicle urinary proteomes
Published in Nature communications (13-06-2024)“…Urine is a complex biofluid that reflects both overall physiologic state and the state of the genitourinary tissues through which it passes. It contains both…”
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7
Two-fraction stereotactic ablative radiotherapy (SABR) versus two-fraction high dose rate (HDR) brachytherapy for localized prostate cancer: Does dose heterogeneity matter?
Published in Radiotherapy and oncology (01-04-2022)“…•PSA kinetics and biochemical failure were similar with two-fractions of SABR or HDR.•Quality of life, acute and late toxicities were no different in the two…”
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8
miRNA‐106a and prostate cancer radioresistance: a novel role for LITAF in ATM regulation
Published in Molecular oncology (01-08-2018)“…Recurrence of high‐grade prostate cancer after radiotherapy is a significant clinical problem, resulting in increased morbidity and reduced patient survival…”
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9
RSPO3 is a prognostic biomarker and mediator of invasiveness in prostate cancer
Published in Journal of translational medicine (15-04-2019)“…While prostate cancer can often manifest as an indolent disease, the development of locally-advanced or metastatic disease can cause significant morbidity or…”
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10
Highly-Sensitive Amplification-Free Analysis of Multiple miRNAs by Capillary Electrophoresis
Published in Analytical chemistry (Washington) (20-01-2015)“…Sets of deregulated microRNAs (miRNAs), termed miRNA signatures, are promising biomarkers for cancer. Validation of miRNA signatures requires a technique that…”
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11
Dll4-notch signalling blockade synergizes combined ultrasound-stimulated microbubble and radiation therapy in human colon cancer xenografts
Published in PloS one (15-04-2014)“…Tumour vasculature acts as an essential lifeline for tumour progression and facilitates metastatic spread. Novel vascular targeting strategies aiming to…”
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12
Pea3 expression promotes the invasive and metastatic potential of colorectal carcinoma
Published in World journal of gastroenterology : WJG (14-12-2014)“…AIM:To investigate the function of Pea3 in colorectal carcinoma(CRC)invasion and metastatic potential.METHODS:The expression of Pea3 during clinical…”
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13
Elective pelvic nodal irradiation in the setting of ultrahypofractionated versus moderately hypofractionated and conventionally fractionated radiotherapy for prostate cancer: Outcomes from 3 prospective clinical trials
Published in Clinical and translational radiation oncology (01-11-2024)“…•Three prospective trials evaluating elective nodal irradiation in the setting of ultrahypofractionated versus moderately hypofractionated and convetionally…”
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14
Targeting PLOD2 suppresses invasion and metastatic potential in radiorecurrent prostate cancer
Published in BJC Reports (01-01-2024)“…Abstract Background Metastatic relapse of prostate cancer after radiotherapy is a significant cause of prostate cancer-related morbidity and mortality. PLOD2…”
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15
Reciprocal interactions between tumour cell populations enhance growth and reduce radiation sensitivity in prostate cancer
Published in Communications biology (04-01-2021)“…Intratumoural heterogeneity (ITH) contributes to local recurrence following radiotherapy in prostate cancer. Recent studies also show that ecological…”
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16
Stereotactic body radiotherapy versus conventional external beam radiotherapy in patients with painful spinal metastases: an open-label, multicentre, randomised, controlled, phase 2/3 trial
Published in The lancet oncology (01-07-2021)“…Conventional external beam radiotherapy is the standard palliative treatment for spinal metastases; however, complete response rates for pain are as low as…”
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17
Basal‐subtype bladder tumours show a ‘hot’ immunophenotype
Published in Histopathology (01-11-2018)“…Aims Basal and luminal molecular subgroups of muscle‐invasive urothelial carcinoma (UC) can be recognised by the use of immunohistochemical markers. Studies…”
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18
Endothelial perturbations and therapeutic strategies in normal tissue radiation damage
Published in Radiation oncology (London, England) (18-12-2014)“…Most cancer patients are treated with radiotherapy, but the treatment can also damage the surrounding normal tissue. Radiotherapy side-effects diminish…”
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19
Delta-Like Ligand 4-Notch Blockade and Tumor Radiation Response
Published in JNCI : Journal of the National Cancer Institute (07-12-2011)Get full text
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20
Reproducibility of PD-L1 immunohistochemistry interpretation across various types of genitourinary and head/neck carcinomas, antibody clones, and tissue types
Published in Human pathology (01-12-2018)“…Programmed death-ligand 1 (PD-L1) expression by tumor cells is a mechanism for down-regulation of antitumor T-cell responses and is a target for immunotherapy…”
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