Search Results - "LIU, Alvin Y"

The opposing action of stromal cell proenkephalin and stem cell transcription factors in prostate cancer differentiation by Liu, Alvin Y

“…Loss of prostate cancer differentiation or de-differentiation leads to an untreatable disease. Patient survival would benefit if this can be prevented or…”
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Prostate cancer research: tools, cell types, and molecular targets by Liu, Alvin Y

“…Multiple cancer cell types are found in prostate tumors. They are either luminal-like adenocarcinoma or less luminal-like and more stem-like non-adenocarcinoma…”
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ERG Status Is Unrelated to PSA Recurrence in Radically Operated Prostate Cancer in the Absence of Antihormonal Therapy by MINNER, Sarah, ENODIEN, Malaika, BRASE, Jan C, LIU, Alvin Y, SCHLÜTER, Hartmut, PANTEL, Klaus, SCHUMACHER, Udo, BOKEMEYER, Carsten, STEUBER, Thomas, GRAEFEN, Markus, SAUTER, Guido, SCHLOMM, Thorsten, SIRMA, Hüseyin, LUEBKE, Andreas M, KROHN, Antje, MAYER, Pascale S, SIMON, Ronald, TENNSTEDT, Pierre, MÜLLER, Julia, SCHOLZ, Laura

“…About 50% of prostate cancers have TMPRSS2-ERG fusions with concurrent ERG overexpression. The aim of this study was to determine whether clinical differences…”
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Deep Learning and Transfer Learning for Optic Disc Laterality Detection: Implications for Machine Learning in Neuro-Ophthalmology by Liu, T. Y. Alvin, Ting, Daniel S. W., Yi, Paul H., Wei, Jinchi, Zhu, Hongxi, Subramanian, Prem S., Li, Taibo, Hui, Ferdinand K., Hager, Gregory D., Miller, Neil R.

“…BACKGROUND:Deep learning (DL) has demonstrated human expert levels of performance for medical image classification in a wide array of medical fields, including…”
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Mass Spectrometric Detection of Tissue Proteins in Plasma by Zhang, Hui, Liu, Alvin Y, Loriaux, Paul, Wollscheid, Bernd, Zhou, Yong, Watts, Julian D, Aebersold, Ruedi

“…It has long been thought that blood plasma could serve as a window into the state of one’s organs in health and disease because tissue-derived proteins…”
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Detection and Verification of Glycosylation Patterns of Glycoproteins from Clinical Specimens Using Lectin Microarrays and Lectin-Based Immunosorbent Assays by Li, Yan, Tao, Sheng-Ce, Bova, G. Steven, Liu, Alvin Y, Chan, Daniel W, Zhu, Heng, Zhang, Hui

“…Aberrant glycosylation is a fundamental characteristic of progression of diseases such as cancer. Therefore, characterization of glycosylation patterns of…”
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High expression of AGR2 in lung cancer is predictive of poor survival by Alavi, Mohammed, Mah, Vei, Maresh, Erin L, Bagryanova, Lora, Horvath, Steve, Chia, David, Goodglick, Lee, Liu, Alvin Y

“…Anterior gradient 2 (AGR2) is a protein disulfide isomerase-like protein widely expressed in many normal tissues as well as cancers. In our study,…”
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Correlation of mRNA and protein levels: cell type-specific gene expression of cluster designation antigens in the prostate by Pascal, Laura E, True, Lawrence D, Campbell, David S, Deutsch, Eric W, Risk, Michael, Coleman, Ilsa M, Eichner, Lillian J, Nelson, Peter S, Liu, Alvin Y

“…: Expression levels of mRNA and protein by cell types exhibit a range of correlations for different genes. In this study, we compared levels of mRNA abundance…”
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Lineage relationship between prostate adenocarcinoma and small cell carcinoma by Kanan, Adelle D, Corey, Eva, Vêncio, Ricardo Z N, Ishwar, Arjun, Liu, Alvin Y

“…Prostate cancer displays different morphologies which, in turn, affect patient outcome. This fact prompted questions about the lineage relationship between…”
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A Highly Sensitive Targeted Mass Spectrometric Assay for Quantification of AGR2 Protein in Human Urine and Serum by Shi, Tujin, Gao, Yuqian, Quek, Sue Ing, Fillmore, Thomas L, Nicora, Carrie D, Su, Dian, Zhao, Rui, Kagan, Jacob, Srivastava, Sudhir, Rodland, Karin D, Liu, Tao, Smith, Richard D, Chan, Daniel W, Camp, David G, Liu, Alvin Y, Qian, Wei-Jun

“…Anterior gradient 2 (AGR2) is a secreted, cancer-associated protein in many types of epithelial cancer cells. We developed a highly sensitive targeted mass…”
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Performance and Limitation of Machine Learning Algorithms for Diabetic Retinopathy Screening: Meta-analysis by Wu, Jo-Hsuan, Liu, T Y Alvin, Hsu, Wan-Ting, Ho, Jennifer Hui-Chun, Lee, Chien-Chang

“…Background Diabetic retinopathy (DR), whose standard diagnosis is performed by human experts, has high prevalence and requires a more efficient screening…”
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A Comprehensive Urine Proteome Database Generated From Patients With Various Renal Conditions and Prostate Cancer by Swensen, Adam C, He, Jingtang, Fang, Alexander C, Ye, Yinyin, Nicora, Carrie D, Shi, Tujin, Liu, Alvin Y, Sigdel, Tara K, Sarwal, Minnie M, Qian, Wei-Jun

“…Urine proteins can serve as viable biomarkers for diagnosing and monitoring various diseases. A comprehensive urine proteome database, generated from a variety…”
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CD90 THY1 is overexpressed in prostate cancer-associated fibroblasts and could serve as a cancer biomarker by True, Lawrence D, Zhang, Hui, Ye, Mingliang, Huang, Chung-Ying, Nelson, Peter S, von Haller, Priska D, Tjoelker, Larry W, Kim, Jong-Seo, Qian, Wei-Jun, Smith, Richard D, Ellis, William J, Liebeskind, Emily S, Liu, Alvin Y

“…A by-product in the processing of prostate tissue for cell sorting by collagenase digestion is the media supernatant that remains after the cells are…”
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Autonomous artificial intelligence increases screening and follow-up for diabetic retinopathy in youth: the ACCESS randomized control trial by Wolf, Risa M., Channa, Roomasa, Liu, T. Y. Alvin, Zehra, Anum, Bromberger, Lee, Patel, Dhruva, Ananthakrishnan, Ajaykarthik, Brown, Elizabeth A., Prichett, Laura, Lehmann, Harold P., Abramoff, Michael D.

“…Diabetic retinopathy can be prevented with screening and early detection. We hypothesized that autonomous artificial intelligence (AI) diabetic eye exams at…”
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Differential expression of anterior gradient gene AGR2 in prostate cancer by Maresh, Erin L, Mah, Vei, Alavi, Mohammad, Horvath, Steve, Bagryanova, Lora, Liebeskind, Emily S, Knutzen, Laura A, Zhou, Yong, Chia, David, Liu, Alvin Y, Goodglick, Lee

“…The protein AGR2 is a putative member of the protein disulfide isomerase family and was first identified as a homolog of the Xenopus laevis gene XAG-2. AGR2…”
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Heterogeneity in Primary and Metastatic Prostate Cancer as Defined by Cell Surface CD Profile by Liu, Alvin Y., Roudier, Martine P., True, Lawrence D.

“…Cluster designation (CD) antigens are cell surface markers that can be used to identify constituent cell populations of an organ. We have previously determined…”
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Prostate cancer cell phenotypes based on AGR2 and CD10 expression by Ho, Melissa E, Quek, Sue-Ing, True, Lawrence D, Morrissey, Colm, Corey, Eva, Vessella, Robert L, Dumpit, Ruth, Nelson, Peter S, Maresh, Erin L, Mah, Vei, Alavi, Mohammed, Kim, Sara R, Bagryanova, Lora, Horvath, Steve, Chia, David, Goodglick, Lee, Liu, Alvin Y

“…The combination of expression patterns of AGR2 (anterior gradient 2) and CD10 by prostate cancer provided four phenotypes that correlated with clinical…”
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The Impact of COVID-19 on Diabetic Retinopathy Monitoring and Treatment by Ahmed, Ishrat, Liu, T. Y. Alvin

“…Purpose of Review Diabetic retinopathy (DR) is one of the leading causes of vision loss worldwide. Although screening and early treatment guidelines for DR…”
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Deep Learning Applications to Classification and Detection of Age-Related Macular Degeneration on Optical Coherence Tomography Imaging: A Review by Koseoglu, Neslihan Dilruba, Grzybowski, Andrzej, Liu, T. Y. Alvin

“…Age-related macular degeneration (AMD) is one of the leading causes of blindness in the elderly, more commonly in developed countries. Optical coherence…”
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The Ethical and Societal Considerations for the Rise of Artificial Intelligence and Big Data in Ophthalmology by Liu, T Y Alvin, Wu, Jo-Hsuan

“…Medical specialties with access to a large amount of imaging data, such as ophthalmology, have been at the forefront of the artificial intelligence (AI)…”
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