Search Results - "LITONJUA, Augusto A"
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Prenatal vitamin D supplementation reduces risk of asthma/recurrent wheeze in early childhood: A combined analysis of two randomized controlled trials
Published in PloS one (27-10-2017)“…We recently published two independent randomized controlled trials of vitamin D supplementation during pregnancy, both indicating a >20% reduced risk of…”
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Meta-analysis of effects of exclusive breastfeeding on infant gut microbiota across populations
Published in Nature communications (09-10-2018)“…Previous studies on the differences in gut microbiota between exclusively breastfed (EBF) and non-EBF infants have provided highly variable results. Here we…”
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Six-Year Follow-up of a Trial of Antenatal Vitamin D for Asthma Reduction
Published in The New England journal of medicine (06-02-2020)“…In a previously published controlled trial, maternal administration of vitamin D during pregnancy was found to protect against wheeze in the offspring at the…”
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A prospective microbiome‐wide association study of food sensitization and food allergy in early childhood
Published in Allergy (Copenhagen) (01-01-2018)“…Background Alterations in the intestinal microbiome are prospectively associated with the development of asthma; less is known regarding the role of microbiome…”
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Is vitamin D deficiency to blame for the asthma epidemic?
Published in Journal of allergy and clinical immunology (01-11-2007)“…In the 1960s, the prevalence of asthma and allergic diseases began to increase worldwide. Currently, the burden of the disease is more than 300 million people…”
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Vitamin D Deficiency, Smoking, and Lung Function in the Normative Aging Study
Published in American journal of respiratory and critical care medicine (01-10-2012)“…Vitamin D has immunomodulatory and antiinflammatory effects that may be modified by cigarette smoke and may affect lung function. To examine the effect of…”
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Factors influencing the infant gut microbiome at age 3-6 months: Findings from the ethnically diverse Vitamin D Antenatal Asthma Reduction Trial (VDAART)
Published in Journal of allergy and clinical immunology (01-02-2017)“…Background The gut microbiome in infancy influences immune system maturation, and may have an important impact on allergic disease risk. Objective We sought to…”
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The nasal methylome as a biomarker of asthma and airway inflammation in children
Published in Nature communications (12-07-2019)“…The nasal cellular epigenome may serve as biomarker of airway disease and environmental response. Here we collect nasal swabs from the anterior nares of 547…”
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Transcriptome analysis of early pregnancy vitamin D status and spontaneous preterm birth
Published in PloS one (29-01-2020)“…We conducted a literature review on the studies that investigated the relationship of preterm birth, including spontaneous preterm birth (sPTB), with vitamin D…”
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Early pregnancy vitamin D status and risk of preeclampsia
Published in The Journal of clinical investigation (01-12-2016)“…Low vitamin D status in pregnancy was proposed as a risk factor of preeclampsia. We assessed the effect of vitamin D supplementation (4,400 vs. 400 IU/day),…”
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Vitamin D supplementation during pregnancy: Effect on the neonatal immune system in a randomized controlled trial
Published in Journal of allergy and clinical immunology (01-01-2018)“…Background Programming of the immune system during fetal development can influence asthma-related risk factors and outcomes in later life. Vitamin D is a…”
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Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study
Published in Journal of allergy and clinical immunology (01-07-2010)“…Background Asthma exacerbations, most often caused by respiratory tract infections, are the leading causes of asthma morbidity and comprise a significant…”
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Persistent DNA methylation changes associated with prenatal mercury exposure and cognitive performance during childhood
Published in Scientific reports (21-03-2017)“…Prenatal exposure to mercury, a known neurotoxic metal, is associated with lower cognitive performance during childhood. Disruption of fetal epigenetic…”
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Sex-specific risk factors for childhood wheeze and longitudinal phenotypes of wheeze
Published in Journal of allergy and clinical immunology (01-12-2016)“…Background Although sexual dimorphism in wheeze and asthma prevalence are well documented, sex-specific risk factors for wheeze and longitudinal wheeze…”
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Rapid DNA Methylation Changes after Exposure to Traffic Particles
Published in American journal of respiratory and critical care medicine (01-04-2009)“…Exposure to particulate air pollution has been related to increased hospitalization and death, particularly from cardiovascular disease. Lower blood DNA…”
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Long-term effects of traffic particles on lung function decline in the elderly
Published in American journal of respiratory and critical care medicine (01-09-2014)“…Few studies have been performed on air pollution effects on lung function in the elderly, a vulnerable population with low reserve capacity, and even fewer…”
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Association of Low Serum 25-Hydroxyvitamin D Levels and Sepsis in the Critically Ill
Published in Critical care medicine (01-01-2014)“…OBJECTIVE:We hypothesized that deficiency in 25-hydroxyvitamin D prior to hospital admission would be associated with sepsis in the critically ill…”
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Vitamin D supplementation in pregnancy, prenatal 25(OH)D levels, race, and subsequent asthma or recurrent wheeze in offspring: Secondary analyses from the Vitamin D Antenatal Asthma Reduction Trial
Published in Journal of allergy and clinical immunology (01-11-2017)“…Background Nutrient trials differ from drug trials because participants have varying circulating levels at entry into the trial. Objective We sought to study…”
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Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population
Published in Nature genetics (01-09-2011)“…Bronchial asthma is a common inflammatory disease caused by the interaction of genetic and environmental factors. Through a genome-wide association study and a…”
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Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age
Published in The American journal of clinical nutrition (01-03-2007)“…BACKGROUND:Vitamin D deficiency and asthma are common at higher latitudes. Although vitamin D has important immunologic effects, its relation with asthma is…”
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