Search Results - "LITMAN, Thomas"

Personalized medicine—concepts, technologies, and applications in inflammatory skin diseases by Litman, Thomas

“…The current state, tools, and applications of personalized medicine with special emphasis on inflammatory skin diseases like psoriasis and atopic dermatitis…”
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The effect of short-chain fatty acids on human monocyte-derived dendritic cells by Nastasi, Claudia, Candela, Marco, Bonefeld, Charlotte Menné, Geisler, Carsten, Hansen, Morten, Krejsgaard, Thorbjørn, Biagi, Elena, Andersen, Mads Hald, Brigidi, Patrizia, Ødum, Niels, Litman, Thomas, Woetmann, Anders

“…The gut microbiota is essential for human health and plays an important role in the pathogenesis of several diseases. Short-chain fatty acids (SCFA), such as…”
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MicroRNAs and potential target interactions in psoriasis by Zibert, John R, Løvendorf, Marianne B, Litman, Thomas, Olsen, Jørgen, Kaczkowski, Bogumil, Skov, Lone

“…Abstract Background Psoriasis is a chronic inflammatory skin disease often seen in patients with a genetic susceptibility. MicroRNAs (miRNA) are endogenous,…”
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Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling by Ewald, David A, Noda, Shinji, Oliva, Margeaux, Litman, Thomas, Nakajima, Saeko, Li, Xuan, Xu, Hui, Workman, Christopher T, Scheipers, Peter, Svitacheva, Naila, Labuda, Tord, Krueger, James G, Suárez-Fariñas, Mayte, Kabashima, Kenji, Guttman-Yassky, Emma

“…Atopic dermatitis (AD) is caused by a complex interplay between immune and barrier abnormalities. Murine models of AD are essential for preclinical assessments…”
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Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection by Esaki, Hitokazu, MD, Ewald, David A., MSc, Ungar, Benjamin, BA, Rozenblit, Mariya, BA, Zheng, Xiuzhong, MSc, Xu, Hui, MSc, Estrada, Yeriel D., BS, Peng, Xiangyu, MSc, Mitsui, Hiroshi, MD, PhD, Litman, Thomas, PhD, Suárez-Fariñas, Mayte, PhD, Krueger, James G., MD, PhD, Guttman-Yassky, Emma, MD, PhD

“…Background The molecular signature of atopic dermatitis (AD) lesions is associated with TH 2 and TH 22 activation and epidermal alterations. However, the…”
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Gene Expression Linked to Reepithelialization of Human Skin Wounds by Ågren, Magnus S, Litman, Thomas, Eriksen, Jens Ole, Schjerling, Peter, Bzorek, Michael, Gjerdrum, Lise Mette Rahbek

“…Our understanding of the regulatory processes of reepithelialization during wound healing is incomplete. In an attempt to map the genes involved in epidermal…”
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Topical Delivery of Hedgehog Inhibitors: Current Status and Perspectives by Pedersen, Kristian Kåber, Høyer-Hansen, Maria Helena, Litman, Thomas, Hædersdal, Merete, Olesen, Uffe Høgh

“…Systemic treatment with hedgehog inhibitors (HHis) is available to treat basal cell carcinomas but their utility is limited by adverse effects. Topical…”
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Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways by Ewald, David A, Malajian, Dana, Krueger, James G, Workman, Christopher T, Wang, Tianjiao, Tian, Suyan, Litman, Thomas, Guttman-Yassky, Emma, Suárez-Fariñas, Mayte

“…Atopic dermatitis (AD) is a common inflammatory skin disease with limited treatment options. Several microarray experiments have been conducted on lesional/LS…”
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The Rectal Cancer microRNAome ― microRNA Expression in Rectal Cancer and Matched Normal Mucosa by GAEDCKE, Jochen, GRADE, Marian, BEISSBARTH, Tim, RIED, Thomas, LITMAN, Thomas, CAMPS, Jordi, SØKILDE, Rolf, KACZKOWSKI, Bogumil, SCHETTER, Aaron J, DIFILIPPANTONIO, Michael J, HARRIS, Curtis C, MICHAEL GHADIMI, B, MØLLER, Soren

“…miRNAs play a prominent role in a variety of physiologic and pathologic biologic processes, including cancer. For rectal cancers, only limited data are…”
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Ancient lineages of the keratin-associated protein (KRTAP) genes and their co-option in the evolution of the hair follicle by Litman, Thomas, Stein, Wilfred D

“…BLAST searches against the human genome showed that of the 93 keratin-associated proteins (KRTAPs) of Homo sapiens, 53 can be linked by sequence similarity to…”
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Inhibition of succinate dehydrogenase activity impairs human T cell activation and function by Nastasi, Claudia, Willerlev-Olsen, Andreas, Dalhoff, Kristoffer, Ford, Shayne L., Gadsbøll, Anne-Sofie Østergaard, Buus, Terkild Brink, Gluud, Maria, Danielsen, Morten, Litman, Thomas, Bonefeld, Charlotte Mennè, Geisler, Carsten, Ødum, Niels, Woetmann, Anders

“…T cell activation is intimately linked to metabolism, as distinct metabolic requirements support the functional and phenotypical differences between quiescent…”
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Regulation of ABCG2 Expression at the 3′ Untranslated Region of Its mRNA through Modulation of Transcript Stability and Protein Translation by a Putative MicroRNA in the S1 Colon Cancer Cell Line by To, Kenneth K. W., Zhan, Zhirong, Litman, Thomas, Bates, Susan E.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Distinct molecular signatures of mild extrinsic and intrinsic atopic dermatitis by Martel, Britta C., Litman, Thomas, Hald, Andreas, Norsgaard, Hanne, Lovato, Paola, Dyring-Andersen, Beatrice, Skov, Lone, Thestrup-Pedersen, Kristian, Skov, Søren, Skak, Kresten, Poulsen, Lars K.

“…Atopic dermatitis (AD) is a common inflammatory skin disease with underlying defects in epidermal function and immune responses. In this study, we used…”
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Ammonia and urea permeability of mammalian aquaporins by Litman, Thomas, Søgaard, Rikke, Zeuthen, Thomas

“…The human aquaporins,AQP3,AQP7, AQP8,AQP9, and possibly AQP10, are permeable to ammonia, and AQP7, AQP9, and possibly AQP3, are permeable to urea. In humans,…”
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A simplified bacterial community found within the epidermis than at the epidermal surface of atopic dermatitis patients and healthy controls by Barnes, Christopher J., Asplund, Maria, Clausen, Maja-Lisa, Rasmussen, Linett, Olesen, Caroline Meyer, Yüksel, Yasemin Topal, Andersen, Paal Skytt, Litman, Thomas, Holmstrøm, Kim, Bay, Lene, Fritz, Blaine Gabriel, Bjarnsholt, Thomas, Agner, Tove, Hansen, Anders Johannes

“…Abstract There has been considerable research into the understanding of the healthy skin microbiome. Similarly, there is also a considerable body of research…”
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Secukinumab and Dead Sea Climatotherapy Impact Resolved Psoriasis Skin Differently Potentially Affecting Disease Memory by Emmanuel, Thomas, Ignatov, Borislav, Bertelsen, Trine, Litman, Thomas, Nielsen, Morten Muhlig, Brent, Mikkel Bo, Touborg, Toke, Rønsholdt, Anders Benjamin, Petersen, Annita, Boye, Mette, Kaaber, Ida, Sortebech, Daniel, Lybæk, Dorte, Steiniche, Torben, Bregnhøj, Anne, Eidsmo, Liv, Iversen, Lars, Johansen, Claus

“…Secukinumab and Dead Sea treatment result in clear skin for many psoriasis patients, through distinct mechanisms. However, recurrence in the same areas after…”
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Skin Barrier and Inflammation Genes Associated with Atopic Dermatitis are Regulated by Interleukin-13 and Modulated by Tralokinumab In vitro by Tollenaere, Maxim A X, Litman, Thomas, Moebus, Lena, Rodriguez, Elke, Stölzl, Dora, Drerup, Katharina, Werfel, Thomas, Schmitt, Jochen, Norsgaard, Hanne, Weidinger, Stephan

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Regional Differences in Neuroinflammation-Associated Gene Expression in the Brain of Sporadic Creutzfeldt-Jakob Disease Patients by Areškevičiūtė, Aušrinė, Litman, Thomas, Broholm, Helle, Melchior, Linea C, Nielsen, Pia R, Green, Alison, Eriksen, Jens O, Smith, Colin, Lund, Eva L

“…Neuroinflammation is an essential part of neurodegeneration. Yet, the current understanding of neuroinflammation-associated molecular events in distinct brain…”
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miRNA Signature in Early-stage Mycosis Fungoides by Sørensen, Sissel T., Litman, Thomas, Gluud, Maria, Celis, Pamela, Torres-Rusillo, Sara, Willerslev-Olsen, Andreas, Ødum, Niels, Iversen, Lars, Lindahl, Lise M.

“…Altered miRNA expressions are assigned pathogenic properties in several cancers including mycosis fungoides and could play a role in the early onset of the…”
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The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer by Gravgaard, Karina H., Lyng, Maria B., Laenkholm, Anne-Vibeke, Søkilde, Rolf, Nielsen, Boye Schnack, Litman, Thomas, Ditzel, Henrik J.

“…Metastases are the major cause of cancer-related deaths, but the mechanisms of the metastatic process remain poorly understood. In recent years, the…”
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